GlpBio

5-HT Receptor

5-HT Receptor(5-羟色胺受体)

5-HT receptor (5-hydroxytryptamine receptors) is a group of GPCRs (G protein-coupled receptors) and LGICs (ligand-gated ion channels) found in the central and peripheral nervous systems.

5-HT Receptor 相关产品(481)

  • GC17857 structure
    GC17857PU 02
    CAS: 313984-77-9
    纯度: >99.00%

    A selective 5-HT 3 receptor antagonist

  • GC17974 structure
    GC17974Latrepirdine dihydrochloride
    CAS: 97657-92-6
    纯度: >99.50% / >98.00%

    A neuroprotective agent

  • GC18112 structure
    GC18112LP 44
    CAS: 824958-12-5
    纯度: >98.00%

    A selective 5-HT 7 receptor agonist

  • GC18244 structure
    GC18244Eltoprazine (hydrochloride)
    CAS: 98206-09-8
    纯度: >99.50%

    A partial agonist of 5-HT 1A , 5-HT 1B , and 5-HT 2B receptors

  • GC19176 structure
    GC19176GSK163090
    CAS: 844903-58-8
    纯度: >99.50%

    GSK163090 是一种有效的、选择性的和具有口服活性的 5-HT1A/1B/1D 受体拮抗剂，pKi 值分别为 9.4/8.5/9.7。

  • GC19294 structure
    GC19294Piboserod
    CAS: 152811-62-6
    纯度: >98.00%

    A selective, potent 5-HT 4 receptor antagonist

  • GC19354 structure
    GC19354TG6-10-1
    CAS: 1415716-58-3
    纯度: >99.50%

    A potent EP 2 receptor antagonist

  • GC19389 structure
    GC19389YL0919
    CAS: 1339058-04-6
    纯度: >99.50%

    YL0919 (YL0919) 是一种具有双重活性的口服抗抑郁药，作为高度选择性的 5-HT 摄取阻滞剂和有效的 5-HT1Areceptor 激动剂 (Ki=0.19 nM)。

  • GC25253 structure
    GC25253Cinitapride Hydrogen Tartrate
    CAS: 1207859-16-2

    Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors

  • GC25259 structure
    GC25259Cisapride hydrate
    CAS: 260779-88-2

    Cisapride (Propulsid, Alimix, Propulsin, Enteropride, Kinestase) acts directly as a selective serotonin 5-HT4 receptor agonist with IC50 of 0.483 μM. And It also acts indirectly as a parasympathomimetic.

  • GC25434 structure
    GC25434Frovatriptan Succinate
    CAS: 158930-09-7

    Frovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.

  • GC25563 structure
    GC25563Lasmiditan succinate
    CAS: 439239-92-6

    Lasmiditan succinate (COL-144, LY573144) is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (Ki=2.21 nM) without vasoconstrictor activity.

  • GC25569 structure
    GC25569Lerisetron
    CAS: 143257-98-1

    Lerisetron (F 0930, F 0930RS) is a 5-HT3 receptor antagonist with IC50 of 0.81μM.

  • GC25756 structure
    GC25756Pirenperone
    CAS: 75444-65-4

    Pirenperone (R-47456, R-50656), a quinazoline derivative, is a selective antagonist of SR-2A (5-HT2 serotonin receptor) when employed in low doses. Pirenperone behaves like a typical neuroleptic when used in higher doses (greater than 0.1 mg/kg).

  • GC25898 structure
    GC25898SB 200646
    CAS: 143797-63-1

    SB 200646 (SB 200646A) is a potent, selective and oral-active antagonist of 5-HT2B/2C over 5-HT2A receptor with 50 fold selectivity. The pKi for rat 5-HT2C receptor, rat 5-HT2B receptor and rat 5-HT2A receptor are 6.9, 7.5 and 5.2, respectively. SB 200646 has electrophysiological and anxiolytic properties in vivo.

  • GC26002 structure
    GC26002Trazodone
    CAS: 19794-93-5
    纯度: >98.00%

    Trazodone (AF-1161) is a 5-HT 2A/2C receptor antagonist that is used as an antidepressant for treating major depressive disorder and anxiety disorders.

  • GC30198 structure
    GC30198Dolasetron Mesylate hydrate
    CAS: 878143-33-0
    纯度: >99.00%

    A 5-HT 3 receptor antagonist

  • GC30206 structure
    GC30206Roluperidone (CYR-101)
    CAS: 359625-79-9
    纯度: >99.50%

    A dual antagonist of 5-HT 2A and σ 2 receptors

  • GC30273 structure
    GC30273Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide)
    CAS: 960151-65-9
    纯度: >99.50%

    Tedatioxetine (Lu AA24530) hydrobromide 可作为 5-HT2A、5-HT2C、5-HT3 和 α；1A-肾上腺素受体拮抗剂，可作为 5-羟色胺和去甲肾上腺素 (NE) 的首选三重再摄取抑制剂 (TRI)。

  • GC30280 structure
    GC30280Chlorpromazine D6 hydrochloride
    CAS: 1228182-46-4
    纯度: >99.50%

    Chlorpromazine D6 hydrochloride是 Chlorpromazine 的氘代物，可被用于 NMR、GC-MS 或 LC-MS 分析中的内标品，用于定量分析。

  • GC30314 structure
    GC303145-HT4 antagonist 1
    CAS: 261766-73-8

    5-HT4antagonist1是一个5-HT4受体拮抗剂，其pKi值为9.6。

  • GC30352 structure
    GC30352Lintopride
    CAS: 107429-63-0

    Lintopride是5HT4拮抗剂，对5HT3有轻微拮抗作用。

  • GC30412 structure
    GC30412Dolasetron (MDL-73147)
    CAS: 115956-12-2
    纯度: >98.00%

    A 5-HT 3 receptor antagonist

  • GC30413 structure
    GC30413Dolasetron Mesylate (MDL-73147EF)
    CAS: 115956-13-3

    A 5-HT 3 receptor antagonist