Alzheimer
Alzheimer(阿尔茨海默病)
Alzheimer
Alzheimer’s disease (AD), a neurodegenerative disorder, is the most common cause of progressive dementia. Two microscopic characteristics of AD are extracellular amyloid plaques and intracellular neurofibrillary tangles. Amyloid β peptide (Aβ), derived from amyloid precursor protein (APP) by sequential protein cleavage, and other metabolites deposit around neurons and form amyloid plaques, which contribute to the disease’s pathogenesis. The neurofibrillary tangles are formed by the aggregation of phosphorylated tau proteins. Under pathogenic conditions, tau accumulates in dendritic spines and interferes with neurotransmission. The Aβoligomer promotes tau enrichment and facilitates disease progress. read more
Alzheimer 相关产品(103)
- GC467206,9-Dichloro-1,2,3,4-tetrahydroacridineCAS: 5396-25-8纯度: >98.00%
A synthetic intermediate in the synthesis of AChE inhibitors
- GC46851Amyloid-β (1-42) Peptide (trifluoroacetate salt)纯度: >95.00%
A 42-amino acid protein fragment of amyloid-β
- GC46992C18 Ganglioside GM1-d3 (d18:1/18:0-d3) (ammonium salt)纯度: >99.00%
A neuropeptide with diverse biological activities
- GC46998C22 Galactosylceramide-d4 (d18:1/22:0-d4)纯度: >99.00%
A neuropeptide with diverse biological activities
- GC47186Deoxy Donepezil (hydrochloride)CAS: 1034439-57-0纯度: >98.00%
A potential impurity found in bulk preparations of donepezil
- GC47196Desloratadine-d4CAS: 2713301-38-1纯度: >99.00%
An internal standard for the quantification of desloratadine
- GC47263Donecopride (fumarate hydrate)纯度: >95.00%
A 5-HT 4 receptor partial agonist and AChE inhibitor
- GC47264Donepezil-d4 (hydrochloride)CAS: 1219798-88-5纯度: >99.00%
An internal standard for the quantification of donepezil
- GC47389Galantamine-d3 (hydrobromide)CAS: 2140262-53-7纯度: >99.00%
An internal standard for the quantification of galantamine
- GC47437Humanin (human) (trifluoroacetate salt)纯度: >95.00%
A neuropeptide with diverse biological activities
- GC48028Rasagiline-13C3 (mesylate)CAS: 1391052-18-8纯度: >95.00%
An internal standard for the quantification of rasagiline
- GC48083sn-Glycerol-3-phosphate (cyclohexyl ammonium salt hydrate)纯度: >95.00%
A neuropeptide with diverse biological activities
- GC49090Nilvadipine-d4CAS: 2928067-26-7纯度: >99.00%
An internal standard for the quantification of nilvadipine
- GC49108Racecadotril-d5CAS: 1246815-11-1纯度: >99.00%
An internal standard for the quantification of racecadotril
- GC49192Piracetam-d6CAS: 2907016-93-5纯度: >99.00%
An internal standard for the quantification of piracetam
- GC49273Glycerophosphorylethanolamine (sodium salt)CAS: 883288-78-6纯度: >90.00%
An active metabolite of phosphatidylethanolamine
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC46720 | 6,9-Dichloro-1,2,3,4-tetrahydroacridine | 5396-25-8 | >98.00% | |
A synthetic intermediate in the synthesis of AChE inhibitors | ||||
| GC46851 | Amyloid-β (1-42) Peptide (trifluoroacetate salt) | - | >95.00% | |
A 42-amino acid protein fragment of amyloid-β | ||||
| GC46992 | C18 Ganglioside GM1-d3 (d18:1/18:0-d3) (ammonium salt) | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46997 | C22 Galactosylceramide (d18:1/22:0) | 74645-25-3 | >98.00% | |
A sphingolipid | ||||
| GC46998 | C22 Galactosylceramide-d4 (d18:1/22:0-d4) | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47186 | Deoxy Donepezil (hydrochloride) | 1034439-57-0 | >98.00% | |
A potential impurity found in bulk preparations of donepezil | ||||
| GC47196 | Desloratadine-d4 | 2713301-38-1 | >99.00% | |
An internal standard for the quantification of desloratadine | ||||
| GC47263 | Donecopride (fumarate hydrate) | - | >95.00% | |
A 5-HT 4 receptor partial agonist and AChE inhibitor | ||||
| GC47264 | Donepezil-d4 (hydrochloride) | 1219798-88-5 | >99.00% | |
An internal standard for the quantification of donepezil | ||||
| GC47389 | Galantamine-d3 (hydrobromide) | 2140262-53-7 | >99.00% | |
An internal standard for the quantification of galantamine | ||||
| GC47437 | Humanin (human) (trifluoroacetate salt) | - | >95.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47563 | L-Glutamic Acid (ammonium salt) | 7558-63-6 | >97.00% | |
An excitatory neurotransmitter | ||||
| GC47746 | NAP 226-90 | 139306-10-8 | >98.00% | |
A metabolite of rivastigmine | ||||
| GC47955 | Phloroglucinol | 108-73-6 | >99.00% | |
A phenol with diverse biological activities | ||||
| GC48028 | Rasagiline-13C3 (mesylate) | 1391052-18-8 | >95.00% | |
An internal standard for the quantification of rasagiline | ||||
| GC48083 | sn-Glycerol-3-phosphate (cyclohexyl ammonium salt hydrate) | - | >95.00% | |
A neuropeptide with diverse biological activities | ||||
| GC48362 | PMX-205 (trifluoroacetate salt) | - | >95.00% | |
A potent antagonist of C5aR | ||||
| GC48969 | Withanone | 27570-38-3 | >90.00% | |
A phytochemical with diverse biological activities | ||||
| GC49024 | Palmitic Acid MaxSpec® Standard | 57-10-3 | >95.00% | |
A long-chain saturated fatty acid | ||||
| GC49090 | Nilvadipine-d4 | 2928067-26-7 | >99.00% | |
An internal standard for the quantification of nilvadipine | ||||
| GC49108 | Racecadotril-d5 | 1246815-11-1 | >99.00% | |
An internal standard for the quantification of racecadotril | ||||
| GC49192 | Piracetam-d6 | 2907016-93-5 | >99.00% | |
An internal standard for the quantification of piracetam | ||||
| GC49273 | Glycerophosphorylethanolamine (sodium salt) | 883288-78-6 | >90.00% | |
An active metabolite of phosphatidylethanolamine | ||||
| GC49306 | Isopimaric Acid | 5835-26-7 | >98.00% | |
A diterpenoid resin acid | ||||