Alzheimer
Alzheimer(阿尔茨海默病)
Alzheimer
Alzheimer’s disease (AD), a neurodegenerative disorder, is the most common cause of progressive dementia. Two microscopic characteristics of AD are extracellular amyloid plaques and intracellular neurofibrillary tangles. Amyloid β peptide (Aβ), derived from amyloid precursor protein (APP) by sequential protein cleavage, and other metabolites deposit around neurons and form amyloid plaques, which contribute to the disease’s pathogenesis. The neurofibrillary tangles are formed by the aggregation of phosphorylated tau proteins. Under pathogenic conditions, tau accumulates in dendritic spines and interferes with neurotransmission. The Aβoligomer promotes tau enrichment and facilitates disease progress. read more
Alzheimer 相关产品(103)
- GC49417L-Serine-13C3CAS: 201595-68-8纯度: >95.00%
An internal standard for the quantification of L-serine
- GC49436L-3-n-ButylphthalideCAS: 3413-15-8纯度: >99.00%
A phthalide with antiplatelet and neuroprotective activities
- GC49461L-Serine-d7CAS: 935275-35-7纯度: >99.00%
An internal standard for the quantification of L-serine
- GC52078Galantamine (hydrobromide)CAS: 69353-21-5纯度: >98.00%
An alkaloid with AChE inhibitory and nAChR potentiating activities
- GC52214Nicotinamide riboside-d4 (triflate)纯度: >95.00%
An internal standard for the quantification of nicotinamide riboside
- GC91977TrkB Agonist Prodrug R13CAS: 1609067-49-3纯度: >95.00%
TrkB Agonist Prodrug R13（R13）是原肌球蛋白相关激酶B（TrkB）激活剂7,8-二羟基黄酮的前药形式。
- GP10049Amyloid Beta-Peptide (12-28) (human)CAS: 107015-83-8纯度: >95.00%
Amyloid Beta-Peptide (12-28)（人）是 Amyloid Beta 蛋白 (1-42) (Aβ (1-42)) 的肽片段。
- GP10057Amyloid β-Peptide (10-20) (human)CAS: 152286-31-2
Amyloid β-Peptide (10-20) (human) 是 Amyloid-β 的片段；肽，可用于神经系统疾病的研究。
- GP10082Amyloid Beta-peptide (25-35) (human)CAS: 131602-53-4纯度: >99.50% / >98.00% / >98.50%
淀粉样蛋白β肽(Aβ) (25-35)(human)是阿尔茨海默病淀粉样蛋白β肽的片段，具有神经毒性作用。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC49417 | L-Serine-13C3 | 201595-68-8 | >95.00% | |
An internal standard for the quantification of L-serine | ||||
| GC49436 | L-3-n-Butylphthalide | 3413-15-8 | >99.00% | |
A phthalide with antiplatelet and neuroprotective activities | ||||
| GC49461 | L-Serine-d7 | 935275-35-7 | >99.00% | |
An internal standard for the quantification of L-serine | ||||
| GC49493 | IRL 1620 (trifluoroacetate salt) | - | >98.00% | |
A peptide ET B receptor agonist | ||||
| GC49557 | Cu-GTSM | 68341-14-0 | >95.00% | |
A copper-containing compound with diverse biological activities | ||||
| GC49815 | Oleuropein aglycone | 31773-95-2 | >98.00% | |
A polyphenol with diverse biological activities | ||||
| GC49913 | Davunetide (acetate) | - | >98.00% | |
A neuroprotective ADNP-derived peptide | ||||
| GC52027 | Isolariciresinol | 548-29-8 | >98.00% | |
A lignan with diverse biological activities | ||||
| GC52047 | Fustin | 20725-03-5 | >98.00% | |
A flavanone with diverse biological activities | ||||
| GC52078 | Galantamine (hydrobromide) | 69353-21-5 | >98.00% | |
An alkaloid with AChE inhibitory and nAChR potentiating activities | ||||
| GC52214 | Nicotinamide riboside-d4 (triflate) | - | >95.00% | |
An internal standard for the quantification of nicotinamide riboside | ||||
| GC52496 | Sulfatide (bovine) (sodium salt) | - | >95.00% | |
A mixture of isolated bovine sulfatides | ||||
| GC65195 | 2-O-Acetyl-20-hydroxyecdysone | 19536-25-5 | >99.00% | |
An ecdysone steroid hormone | ||||
| GC72054 | Obovatol | 83864-78-2 | >99.00% | |
Obovatol是一种从厚朴叶中分离出来的联苯醚木脂素。 | ||||
| GC91070 | p-methyl-N-salicyloyl Tryptamine | 1371564-45-2 | >98.00% | |
一种神经保护剂 | ||||
| GC91621 | WLB-89462 | 2849471-75-4 | >98.00% | |
WLB-89462 is a ligand of sigma intracellular receptor 2 (σ2 receptor). | ||||
| GC91899 | Carmustine-d8 | - | >99.00% | |
Carmustine-d8旨在用作气相色谱或液相色谱-质谱定量卡莫司汀的内标。 | ||||
| GC91977 | TrkB Agonist Prodrug R13 | 1609067-49-3 | >95.00% | |
TrkB Agonist Prodrug R13（R13）是原肌球蛋白相关激酶B（TrkB）激活剂7,8-二羟基黄酮的前药形式。 | ||||
| GP10006 | Myelin Basic Protein (68-82), guinea pig | 98474-59-0 | - | |
髓鞘碱性蛋白 (68-82)，豚鼠是髓鞘碱性蛋白 (MBP) 的片段。 | ||||
| GP10010 | COG 133 | 514200-66-9 | - | |
A peptide fragment of ApoE and an α7 nAChR antagonist | ||||
| GP10046 | Amyloid Precursor C-Terminal Peptide | - | - | |
For beta amyloid generation | ||||
| GP10049 | Amyloid Beta-Peptide (12-28) (human) | 107015-83-8 | >95.00% | |
Amyloid Beta-Peptide (12-28)（人）是 Amyloid Beta 蛋白 (1-42) (Aβ (1-42)) 的肽片段。 | ||||
| GP10057 | Amyloid β-Peptide (10-20) (human) | 152286-31-2 | - | |
Amyloid β-Peptide (10-20) (human) 是 Amyloid-β 的片段；肽，可用于神经系统疾病的研究。 | ||||
| GP10082 | Amyloid Beta-peptide (25-35) (human) | 131602-53-4 | >99.50% / >98.00% / >98.50% | |
淀粉样蛋白β肽(Aβ) (25-35)(human)是阿尔茨海默病淀粉样蛋白β肽的片段，具有神经毒性作用。 | ||||