(E)-Anethol is a phenylpropanoid that has been found in P. anisum seed oil and has antifungal and antioxidant activity.1,2,3 It is active against fermentatively growing S. cerevisiae under hypoxic, but not normoxic, conditions (MIC = 100 ?g/ml), and against C. parapsilosis when used at a concentration of 15% w/w.2,3 (E)-Anethol has antioxidant activity in a Trolox equivalent antioxidant capacity (TEAC) assay but does not scavenge 2,2-diphenyl-1-picrylhydrazel (DPPH) radicals in a cell-free assay.3
1.Embong, M.B., and Hadziyev, D.Essential oils from spices grown in Alberta: Anise oil (Pimpinella anisum)J. Plant Sci.57(3)681-688(1977) 2.Fujita, K., and Kubo, I.Potentiation of fungicidal activities of trans-anethole against Saccharomyces cerevisiae under hypoxic conditionsJ. Biosci. Bioeng.98(6)490-492(2004) 3.Donati, M., Mondin, A., Chen, Z., et al.Radical scavenging and antimicrobial activities of Croton zehntneri, Pterodon emarginatus and Schinopsis brasiliensis essential oils and their major constituents: Estragole, trans-anethole, β-caryophyllene and myrceneNat. Prod. Res.29(10)939-946(2014)