Microbiology & Virology

Microbiology & Virology(微生物学 & 病毒学)

Virology

A virus is a small infectious agent that replicates inside living cells. Viruses cause many human diseases from small illnesses, like influenza, to more deadly diseases, like hepatitis B and HIV. Our body’s immune system defends against viral infection by generating specific antibodies to bind to and neutralize viral particles and by cell mediated immunity that destroys infected host cells. read more

研究方向

Microbiology & Virology 相关产品(3513)

  • GC61158 structure
    GC61158ONO-5334
    CAS: 868273-90-9
    纯度: >99.50%

    ONO-5334是一种强效、选择性和口服活性的组织蛋白酶K(cathepsinK)抑制剂,对人、兔和大鼠组织蛋白酶K的作用值分别为0.10nM、0.049nM和0.85nM。ONO-5334是一种有效的抗SAR-COV-2病毒活性的抗病毒化合物,其EC50值为500nM。ONO-5334有潜力用于骨质疏松症以及COVID-19的相关研究。

  • GC61163 structure
    GC61163Oxysanguinarine
    CAS: 548-30-1

    Oxysanguinarine(Hydroxysanguinarine;8-Oxosanguinarine)是来自Meconopsissimplicifolia的小檗生物碱,具有抗疟(antimalarial)活性。

  • GC61164 structure
    GC61164Oxytetracycline hydrochloride
    CAS: 2058-46-0
    纯度: >98.00%

    A broad-spectrum antibiotic

  • GC61168 structure
    GC61168Peldesine
    CAS: 133432-71-0
    纯度: >98.00%

    Peldesine(BCX34)是一种有效的,竞争性,可逆和口服活性的嘌呤核苷磷酸化酶(PNP)抑制剂,对人,大鼠和小鼠红细胞(RBC)PNP的IC50分别为36nM,5nM和32nM。Peldesine还是一种T细胞(T-cell)增殖抑制剂,IC50为800nM。Peldesine可用于皮肤T细胞淋巴瘤,牛皮癣和HIV感染的研究。

  • GC61171 structure
    GC61171Pentosan Polysulfate Sodium (W/W 43%) 
    CAS: 140207-93-8
    纯度: 不显示

    PentosanPolysulfateSodium是一种口服生物可利用的半合成药物,具有抗炎和促软骨生成的特性。PentosanPolysulfateSodium也是一种有效和选择性的抗HIV药物。PentosanPolysulfateSodium用于间质性膀胱炎的研究。

  • GC61179 structure
    GC61179Phenazine methylsulfate
    CAS: 299-11-6
    纯度: >98.00%

    A free radical generator

  • GC61185 structure
    GC61185Picropodophyllone
    CAS: 477-48-5

    Picropodophyllone是一种从Podophyllumhexandrum的叶子中分离出来的芳基四氢呋喃木脂素,具有抗真菌活性。

  • GC61190 structure
    GC61190Piperonyl butoxide
    CAS: 51-03-6
    纯度: >99.00%

    An insecticide synergist

  • GC61196 structure
    GC61196Polymyxin B nonapeptide TFA
    CAS: 2220175-42-6
    纯度: >98.00%

    PolymyxinBnonapeptideTFA是一种阳离子环肽。PolymyxinBnonapeptideTFA是经酶裂解PolymyxinB而产生的衍生物,与PolymyxinB相比,PolymyxinBnonapeptideTFA毒性低,缺乏杀菌活性,仍具有破坏革兰氏阴性菌外膜的能力。

  • GC61204 structure
    GC61204Posaconazole-D4
    CAS: 1133712-26-1

    Posaconazole-D4是Posaconazole的氘化标记形式。Posaconazole是一种广谱的,二代三唑类物质,具有抗真菌作用。

  • GC61222 structure
    GC61222Purfalcamine
    CAS: 1038620-68-6
    纯度: >99.50%

    Purfalcamine是一种具有口服活性,选择性的恶性疟原虫钙依赖性蛋白激酶1(PfCDPK1)抑制剂,IC50为17nM,EC50为230nM。Purfalcamine具有抗疟疾活性,可以引起疟原虫在裂殖体阶段的发育停滞。

  • GC61229 structure
    GC61229Quinacrine dihydrochloride
    CAS: 69-05-6
    纯度: >99.00%

    Quinacrine 2HCl(Quinacrine dihydrochloride) is a lipophilic cationic drug with multiple actions that is commonly used as an anti-protozoal agent. Quinacrine is an effective phospholipase A2 inhibitor.

  • GC61231 structure
    GC61231Quinine hydrochloride dihydrate
    CAS: 6119-47-7
    纯度: >99.00%

    An antimalarial agent

  • GC61240 structure
    GC61240Remdesivir O-desphosphate acetonide impurity
    CAS: 1191237-80-5
    纯度: >99.50%

    An intermediate in the synthesis of remdesivir

  • GC61246 structure
    GC61246Rifalazil
    CAS: 129791-92-0
    纯度: >98.00%

    Rifalazil(ABI-1648;KRM-1648)是利福霉素衍生物,可抑制细菌依赖DNA的RNA聚合酶(RNApolymerase)并阻断RNA聚合酶中的β亚基从而杀死细菌感染的细胞。Rifalazil(ABI-1648;KRM-1648)是一种抗生素(antibiotic),对分枝杆菌,革兰氏阳性细菌,幽门螺杆菌,肺炎衣原体和沙眼衣原体有抑制作用,其MIC值在0.00025至0.0025μg/ml之间。Rifalazil(ABI-1648;KRM-1648)有潜力用于衣原体感染,梭菌相关性腹泻菌感染 (CDAD)和结核病(TB)研究的相关研究。

  • GC61258 structure
    GC61258Saccharin sodium hydrate
    CAS: 82385-42-0
    纯度: >98.00%

    Saccharin (O-Sulfobenzimide, O-Benzoic sulfimide, Saccharimide) is an artificial sweetener with effectively no food energy.

  • GC61265 structure
    GC61265Sapienic acid sodium
    CAS: 217477-25-3
    纯度: >98.00%

    Sapienicacidsodium是一种常见于皮肤和粘膜中的脂肪酸,对皮肤和口腔中发现的革兰氏阳性和革兰氏阴性细菌具有可变的抗菌活性。Sapienicacidsodium对血链球菌,微生物链球菌和核纤梭菌具有活性,其MBC值分别为31.3μg/mL,375.0μg/mL和93.8μg/mL。

  • GC61276 structure
    GC61276Silver sulfadiazine
    CAS: 22199-08-2
    纯度: >98.00%

    Silver sulfadiazine is a bactericidal for many gram- negative and gram-positive bacteria as well as being effective against yeast.

  • GC61277 structure
    GC61277Sinapaldehyde
    CAS: 4206-58-0
    纯度: >99.50%

    Sinapaldehyde可从Rhodamniadumetorum茎中分离,对耐甲氧西林的金黄色葡萄球菌(MRSA0)和大肠杆菌具有中等程度的抗菌作用,MIC值都为128μg/mL。

  • GC61284 structure
    GC61284Soyasaponin II
    CAS: 55319-36-3
    纯度: >99.50%

    SoyasaponinII是具有抗病毒活性的皂苷。SoyasaponinII抑制HSV-1,HCMV,流感病毒和HIV-1的复制。SoyasaponinII对HSV-1复制显示出有效的抑制作用。SoyasaponinII作为YB-1磷酸化和NLRP3炎性小体引发的抑制剂,可保护小鼠免受LPS/GalN诱导的急性肝衰竭。

  • GC61289 structure
    GC61289Spergualin trihydrochloride
    CAS: 80952-47-2

    Spergualintrihydrochloride是一个天然产物,最初在芽孢杆菌BMG162-aF2菌株的培养滤液中作为抗生素被鉴定出。

  • GC61297 structure
    GC61297Stearyl glycyrrhetinate
    CAS: 13832-70-7

    Stearylglycyrrhetinate是甘草提取物中的主要成分之一,对金黄色葡萄球菌菌株的MIC大于256mg/L。Stearylglycyrrhetinate具有抗菌(antibacterial)作用。

  • GC61299 structure
    GC61299Sulfadiazine D4
    CAS: 1020719-78-1
    纯度: >98.00%

    An internal standard for the quantification of sulfadiazine

  • GC61300 structure
    GC61300Sulfadimethoxine D4
    CAS: 1020719-80-5

    SulfadimethoxineD4(SulphadimethoxineD4)是Sulfadimethoxine(Sulphadimethoxine)的氘代物。Sulfadimethoxine是磺胺类抗生素,用于多种感染,包括呼吸道、泌尿道、肠道和软组织感染的研究。