Autophagy
Autophagy(自噬)
Autophagy is a catabolic process which degrades and recycles long-lived proteins and cytoplasmic organelles through lysosome. It plays an important role in growth regulation and maintenance of homeostasis.
Autophagy 相关产品(1140)
- GC424144-hydroxy TolbutamideCAS: 5719-85-7纯度: >98.00% / >99.50%
4-Hydroxy Tolbutamide是第一代磺酰脲类降血糖药甲苯磺丁脲在人体内经CYP2C9代谢的主要产物。
- GC43048C18 dihydro Ceramide (d18:0/18:0)CAS: 2304-80-5纯度: >98.00% / >99.00%
C18 dihydro Ceramide (d18:0/18:0)是一种生物活性鞘脂，也是缺乏4,5-反式双键的C18 ceramide从头合成的前体。
- GC43599Emetine (hydrochloride)CAS: 316-42-7纯度: >85.00% / >98.00%
An alkaloid with diverse biological activities
- GC43922Isovaleryl-L-carnitine (chloride)CAS: 139144-12-0纯度: >95.00% / >98.00%
Isovaleryl-L-carnitine (chloride)是L-肉碱的类似物，可延迟小鼠C2.8肝细胞中起始的凋亡细胞死亡。
- GC44346N-Desethylamiodarone (hydrochloride)CAS: 96027-74-6纯度: >98.00% / >99.00%
N-Desethylamiodarone (hydrochloride)是amiodarone的主要代谢产物，可抑制大鼠中细胞色素P4502D6 (CYP2D6)的活性。
- GC44400Niclosamide (ethanolamine salt)CAS: 1420-04-8纯度: >98.00%
氯硝柳胺是一种经美国食品和药物管理局 (FDA) 批准用于治疗肠道蛔虫感染的驱虫药。
- GC44680Pregnenolone sulfate (sodium salt)CAS: 1852-38-6纯度: >95.00% / >98.00%
Pregnenolone sulfate (sodium salt)是一种孕烯醇酮的神经活性代谢产物，对氨基丁酸A型受体（GABA A R）的IC 50 值为26±2μmol/L，对不含γ亚基的GABA A R的IC 50 值为18±3μmol/L。
- GC44856Rutin (hydrate)CAS: 250249-75-3纯度: >98.00%
A flavonoid glycoside with diverse biological activities
- GC45064Tomatidine (hydrochloride)CAS: 6192-62-7纯度: >98.00%
A steroidal alkaloid with diverse biological activities
- GC45187Zoledronic Acid (hydrate)CAS: 165800-06-6纯度: >98.00%
A bisphosphonate that inhibits bone resorption
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC41625 | Oroxylin A | 480-11-5 | >98.00% | |
A flavonoid with diverse biological activities | ||||
| GC42414 | 4-hydroxy Tolbutamide | 5719-85-7 | >98.00% / >99.50% | |
4-Hydroxy Tolbutamide是第一代磺酰脲类降血糖药甲苯磺丁脲在人体内经CYP2C9代谢的主要产物。 | ||||
| GC42677 | ABO (hydrochloride) | 2309172-24-3 | >95.00% | |
A modulator of annexin A7 | ||||
| GC43048 | C18 dihydro Ceramide (d18:0/18:0) | 2304-80-5 | >98.00% / >99.00% | |
C18 dihydro Ceramide (d18:0/18:0)是一种生物活性鞘脂，也是缺乏4,5-反式双键的C18 ceramide从头合成的前体。 | ||||
| GC43105 | C8 Ceramide (d18:1.8:0) | 74713-59-0 | >98.00% | |
A cell-permeable ceramide analog | ||||
| GC43265 | Chromomycin A2 | 6992-70-7 | >98.00% | |
An antibacterial and anticancer aureolic acid | ||||
| GC43321 | CPTH6 (hydrobromide) | 2321332-57-2 | >98.00% | |
A Gcn5 and pCAF HAT inhibitor | ||||
| GC43354 | Cysmethynil | 851636-83-4 | >98.00% | |
An inhibitor of protein prenylation | ||||
| GC43359 | Cytochalasin E | 36011-19-5 | >98.00% | |
Inhibitor of actin polymerization | ||||
| GC43599 | Emetine (hydrochloride) | 316-42-7 | >85.00% / >98.00% | |
An alkaloid with diverse biological activities | ||||
| GC43922 | Isovaleryl-L-carnitine (chloride) | 139144-12-0 | >95.00% / >98.00% | |
Isovaleryl-L-carnitine (chloride)是L-肉碱的类似物，可延迟小鼠C2.8肝细胞中起始的凋亡细胞死亡。 | ||||
| GC43999 | Ketanserin (tartrate) | 83846-83-7 | >99.50% | |
A potent 5-HT 2 receptor antagonist | ||||
| GC44059 | LG 100268 | 153559-76-3 | >99.00% | |
LG 100268 是一种高效、选择性的视黄醇X受体(RXR)激动剂，EC 50 值为4nM，可强力激活RXR同源二聚体。 | ||||
| GC44290 | NAADP (sodium salt) | - | >95.00% | |
A secondary messenger that induces calcium mobilization | ||||
| GC44346 | N-Desethylamiodarone (hydrochloride) | 96027-74-6 | >98.00% / >99.00% | |
N-Desethylamiodarone (hydrochloride)是amiodarone的主要代谢产物，可抑制大鼠中细胞色素P4502D6 (CYP2D6)的活性。 | ||||
| GC44400 | Niclosamide (ethanolamine salt) | 1420-04-8 | >98.00% | |
氯硝柳胺是一种经美国食品和药物管理局 (FDA) 批准用于治疗肠道蛔虫感染的驱虫药。 | ||||
| GC44464 | NSC 109555 | 15427-93-7 | >98.00% | |
An inhibitor of Chk2 | ||||
| GC44680 | Pregnenolone sulfate (sodium salt) | 1852-38-6 | >95.00% / >98.00% | |
Pregnenolone sulfate (sodium salt)是一种孕烯醇酮的神经活性代谢产物，对氨基丁酸A型受体（GABA A R）的IC 50 值为26±2μmol/L，对不含γ亚基的GABA A R的IC 50 值为18±3μmol/L。 | ||||
| GC44797 | Quinacrine analog 34 | 1411646-44-0 | >98.00% | |
An autophagy inhibitor | ||||
| GC44839 | Ridaifen-B | 886465-70-9 | >98.00% | |
An analog of tamoxifen | ||||
| GC44856 | Rutin (hydrate) | 250249-75-3 | >98.00% | |
A flavonoid glycoside with diverse biological activities | ||||
| GC45064 | Tomatidine (hydrochloride) | 6192-62-7 | >98.00% | |
A steroidal alkaloid with diverse biological activities | ||||
| GC45099 | U-0126 | 109511-58-2 | >98.00% | |
A MEK inhibitor and AMPK activator | ||||
| GC45187 | Zoledronic Acid (hydrate) | 165800-06-6 | >98.00% | |
A bisphosphonate that inhibits bone resorption | ||||