GlpBio

Autophagy

Autophagy(自噬)

Autophagy is a catabolic process which degrades and recycles long-lived proteins and cytoplasmic organelles through lysosome. It plays an important role in growth regulation and maintenance of homeostasis.

Autophagy 相关产品(1140)

  • GC14707 structure
    GC14707Purvalanol A
    CAS: 212844-53-6
    纯度: >99.00%

    A selective inhibitor of cyclin-dependent kinases

  • GC14749 structure
    GC14749ALLO-1
    CAS: 37468-32-9

    A smoothened antagonist

  • GC14764 structure
    GC14764Lamotrigine
    CAS: 84057-84-1
    纯度: >99.50%

    An anticonvulsant

  • GC14769 structure
    GC14769Carvedilol
    CAS: 72956-09-3
    纯度: >99.50% / >98.00%

    Carvedilol是一种非选择性α1和β-肾上腺素能受体（Ars）的拮抗剂。

  • GC14787 structure
    GC14787Curcumin
    CAS: 458-37-7
    纯度: >98.00%

    A yellow pigment with diverse biological activities

  • GC14797 structure
    GC14797IU1
    CAS: 314245-33-5
    纯度: >99.00% / >98.00%

    IU1是一种细胞可渗透的、可逆的选择性蛋白酶体抑制剂，对USP14的 IC 50 为 4.7μM。

  • GC14803 structure
    GC14803STF 31
    CAS: 724741-75-7

    STF 31是一种具有细胞通透性的葡萄糖转运蛋白1（GLUT1）的抑制剂，IC₅₀为1μM。

  • GC14806 structure
    GC14806Vinorelbine ditartrate
    CAS: 125317-39-7
    纯度: >98.00%

    Vinorelbine ditartrate是一种抗有丝分裂药物，是紫杉醇（Paclitaxel）的一种半合成衍生物，通过抑制肿瘤细胞的微管聚合来发挥抗肿瘤作用，主要用于治疗非小细胞肺癌和转移性乳腺癌等恶性肿瘤。

  • GC14820 structure
    GC14820(S)-Naproxen
    CAS: 22204-53-1
    纯度: >99.50%

    An NSAID and COX inhibitor

  • GC14827 structure
    GC14827Linagliptin (BI-1356)
    CAS: 668270-12-0
    纯度: >99.50%

    A potent DPP-4 inhibitor

  • GC14882 structure
    GC14882Salinomycin
    CAS: 53003-10-4
    纯度: >98.00%

    A selective cancer stem cell inhibitor

  • GC14892 structure
    GC14892Clemastine Fumarate
    CAS: 14976-57-9
    纯度: >99.50%

    Clemastine Fumarate是一种非处方抗组胺药和毒蕈碱受体阻断剂，在多发性硬化症（MS）中具有髓鞘再生潜力。

  • GC14906 structure
    GC14906Crenolanib (CP-868596)
    CAS: 670220-88-9
    纯度: >99.50%

    An inhibitor of PDGFRα/β and FLT3

  • GC14914 structure
    GC14914KM 11060
    CAS: 774549-97-2
    纯度: >99.50%

    A F508del-CFTR corrector

  • GC14918 structure
    GC1491810074-G5
    CAS: 413611-93-5

    An inhibitor of c-Myc/Max dimerization

  • GC14920 structure
    GC14920VX-661
    CAS: 1152311-62-0
    纯度: >98.00%

    An investigational compound that promotes the maturation of delta F508 CFTR

  • GC14945 structure
    GC14945Sirtinol
    CAS: 410536-97-9
    纯度: >98.00%

    Inhibitor of sirtuin deacetylases

  • GC14961 structure
    GC14961Cytarabine hydrochloride
    CAS: 69-74-9
    纯度: >99.00%

    A nucleoside analog and prodrug form of ara-CTP

  • GC14968 structure
    GC14968Esmolol HCl
    CAS: 81161-17-3
    纯度: >99.00%

    A β 1 -AR antagonist

  • GC14969 structure
    GC14969Idarubicin HCl
    CAS: 57852-57-0
    纯度: >99.50%

    Idarubicin HCl是一种口服蒽环类抗白血病药物。

  • GC15002 structure
    GC15002Sodium Phenylbutyrate
    CAS: 1716-12-7
    纯度: >99.50%

    Sodium Phenylbutyrate是一种组蛋白去乙酰化酶（HDAC）抑制剂。

  • GC15004 structure
    GC15004URMC-099
    CAS: 1229582-33-5
    纯度: >99.50%

    URMC-099作为一种基于7-氮杂吲哚的MLK3抑制剂，其IC50为14 nM，可特异性影响参与疾病病理生物学的特定aβ物种。

  • GC15014 structure
    GC15014A-867744
    CAS: 1000279-69-5
    纯度: >99.50%

    A positive allosteric modulator of α7 nAChRs

  • GC15022 structure
    GC15022Vandetanib (ZD6474)
    CAS: 443913-73-3
    纯度: >99.50%

    A multi-kinase inhibitor