MMP
MMP(基质金属蛋白酶)
Matrix metalloproteinases (MMPs) are a family of zinc-dependent neutral endopeptidases, generally consisting of a single peptide, a propeptide domain, a catalytic domain with a highly conserved zinc-binding site and a haemopexin-like domain, that catalyze the degradation of all components of the extracellular matrix. Multiple studies have shown that MMPs are overexpressed in malignant tumor and involved in the process of tumor growth, invasion and metastasis. Thus, synthetic and naturally occurring MMP inhibitions have been investigated as anti-cancer agents for the treatment of a variety of cancers, which are divided into three pharmacologic categories, including collagen peptidomimetics and nonpeptidomimetics, tetracycline derivatives and bisphosphonates.
MMP 相关产品(191)
- GC45086Trigalacturonic AcidCAS: 6037-45-2纯度: >95.00%
三半乳糖醛酸是一种低聚糖，可抑制番茄植物中的蛋白酶活性（ED50 \u003d 2.6 μg/植物）。
- GC453414-Amino-6-chloro-1,3-benzenedisulfonamideCAS: 121-30-2纯度: >98.00%
A carbonic anhydrase inhibitor
- GC45398Captopril-d3CAS: 1356383-38-4纯度: >99.00%
An internal standard for the quantification of captopril
- GC45818Metoclopramide-d3CAS: 1216522-89-2纯度: >99.00%
An internal standard for the quantification of metoclopramide
- GC459781,10-Phenanthroline (hydrate)CAS: 5144-89-8纯度: >99.00% / >99.50%
A metal chelator and inhibitor of metalloproteases
- GC46854Anastrozole-d12CAS: 120512-32-5纯度: >99.00%
An internal standard for the quantification of anastrozole
- GC46890Atorvastatin-d5 (calcium salt)CAS: 222412-82-0纯度: >99.00%
An internal standard for the quantification of atorvastatin
- GC47042Carfilzomib-d8CAS: 1537187-53-3纯度: >99.00%
An internal standard for the quantification of carfilzomib
- GC47117Colchicine-d6CAS: 1217651-73-4纯度: >99.00%
An internal standard for the quantification of colchicine
- GC47351Fingolimod-d4CAS: 1346747-38-3纯度: >97.50%
An internal standard for the quantification of fingolimod
- GC47366Flurbiprofen-d3CAS: 1185133-81-6纯度: >99.00%
An internal standard for the quantification of flurbiprofen
- GC47647Methiocarb-d3CAS: 1581694-94-1纯度: >99.00%
An internal standard for the quantification of methiocarb
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC44990 | Tanomastat | 179545-77-8 | >98.00% | |
An inhibitor of MMP-2, -3, and -9 | ||||
| GC45086 | Trigalacturonic Acid | 6037-45-2 | >95.00% | |
三半乳糖醛酸是一种低聚糖，可抑制番茄植物中的蛋白酶活性（ED50 \u003d 2.6 μg/植物）。 | ||||
| GC45090 | Triparanol | 78-41-1 | >98.00% | |
An inhibitor of DHCR24 | ||||
| GC45177 | Z-AEVD-FMK | 1135688-47-9 | >95.00% | |
A caspase-10 inhibitor | ||||
| GC45341 | 4-Amino-6-chloro-1,3-benzenedisulfonamide | 121-30-2 | >98.00% | |
A carbonic anhydrase inhibitor | ||||
| GC45398 | Captopril-d3 | 1356383-38-4 | >99.00% | |
An internal standard for the quantification of captopril | ||||
| GC45440 | Doxycycline-d3 (hyclate) | - | >99.00% | |
一种用于量化多西环素的内部标准 | ||||
| GC45818 | Metoclopramide-d3 | 1216522-89-2 | >99.00% | |
An internal standard for the quantification of metoclopramide | ||||
| GC45978 | 1,10-Phenanthroline (hydrate) | 5144-89-8 | >99.00% / >99.50% | |
A metal chelator and inhibitor of metalloproteases | ||||
| GC46026 | TMI 1 | 287403-39-8 | >98.00% | |
An ADAM and MMP inhibitor | ||||
| GC46220 | SD 2590 (hydrochloride) | 226395-93-3 | >98.00% | |
An MMP inhibitor | ||||
| GC46769 | Abametapir | 1762-34-1 | >98.00% | |
A building block and an insecticide | ||||
| GC46779 | Acequinocyl | 57960-19-7 | >98.00% | |
A naphthoquinone acaricide | ||||
| GC46820 | AHU377-d4 | 1884269-07-1 | >99.00% | |
An internal standard for the quantification of AHU377 | ||||
| GC46854 | Anastrozole-d12 | 120512-32-5 | >99.00% | |
An internal standard for the quantification of anastrozole | ||||
| GC46890 | Atorvastatin-d5 (calcium salt) | 222412-82-0 | >99.00% | |
An internal standard for the quantification of atorvastatin | ||||
| GC47042 | Carfilzomib-d8 | 1537187-53-3 | >99.00% | |
An internal standard for the quantification of carfilzomib | ||||
| GC47117 | Colchicine-d6 | 1217651-73-4 | >99.00% | |
An internal standard for the quantification of colchicine | ||||
| GC47326 | Etoxazole | 153233-91-1 | >98.00% | |
An organofluorine acaricide | ||||
| GC47339 | Fenpropimorph | 67564-91-4 | >98.00% | |
A fungicide that inhibits the sterol pathway | ||||
| GC47351 | Fingolimod-d4 | 1346747-38-3 | >97.50% | |
An internal standard for the quantification of fingolimod | ||||
| GC47366 | Flurbiprofen-d3 | 1185133-81-6 | >99.00% | |
An internal standard for the quantification of flurbiprofen | ||||
| GC47646 | Methiocarb | 2032-65-7 | >98.00% | |
A carbamate pesticide | ||||
| GC47647 | Methiocarb-d3 | 1581694-94-1 | >99.00% | |
An internal standard for the quantification of methiocarb | ||||