Drug Metabolite
Drug Metabolite(药物代谢物)
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
Drug Metabolite 相关产品(498)
- GC52132N-desmethyl Diltiazem (hydrochloride)CAS: 130606-60-9纯度: >90.00%
An active metabolite of diltiazem
- GC522275-(3',4'-Dihydroxyphenyl)-γ-ValerolactoneCAS: 21618-92-8纯度: >95.00%
An active metabolite of various polyphenols
- GC523243-(3-Hydroxyphenyl)propionic Acid sulfateCAS: 86321-32-6纯度: >95.00%
A metabolite of certain phenols and glycosides
- GC60132DesmethylnortriptylineCAS: 4444-42-2
Desmethylnortriptyline 是 Nortriptyline 的代谢产物。Nortriptyline 是三环类抗抑郁药，是 Amitriptyline 的主要活性代谢产物，用于缓解抑郁症症状。
- GC60367Tofacitinib metabolite-1CAS: 1640971-51-2纯度: >99.00%
Tofacitinib metabolite-1 是 Tofacitinib 的代谢物, JAK 抑制剂。Tofacitinib metabolite-1 可用于 Tofacitinib 的药动力学和代谢研究。
- GC60399(E)-10-HydroxynortriptylineCAS: 47132-16-1纯度: >99.50%
An active metabolite of amitriptyline and nortriptyline
- GC60410(Rac)-3′-Hydroxy simvastatinCAS: 126313-98-2
(Rac)-3′-Hydroxysimvastatin是一种Simvastatin代谢物。Simvastatin是一种竞争性的HMG-CoA还原酶抑制剂，Ki值为0.2nM。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC52029 | 2-Aminoflubendazole | 82050-13-3 | >95.00% | |
A metabolite of flubendazole | ||||
| GC52033 | S-Methyl-D-penicillamine | 29913-84-6 | >95.00% | |
A metabolite of D-penicillamine | ||||
| GC52035 | Esmolol Acid (hydrochloride) | 83356-60-9 | >98.00% | |
An active metabolite of esmolol | ||||
| GC52045 | N-desmethyl Azelastine | 47491-38-3 | >98.00% | |
An active metabolite of azelastine | ||||
| GC52052 | Dofetilide N-oxide | 144449-71-8 | >98.00% | |
A metabolite of dofetilide | ||||
| GC52054 | Ranitidine S-oxide | 73851-70-4 | >90.00% | |
A metabolite of ranitidine | ||||
| GC52059 | AMOZ | 43056-63-9 | >98.00% | |
A metabolite of furaltadone | ||||
| GC52060 | Trimipramine N-oxide | 14171-70-1 | >90.00% | |
An active metabolite of trimipramine | ||||
| GC52074 | Loratadine N-oxide | 165739-62-8 | >95.00% | |
A metabolite of loratadine | ||||
| GC52076 | Temozolomide Acid | 113942-30-6 | >98.00% | |
An active metabolite of temozolomide | ||||
| GC52132 | N-desmethyl Diltiazem (hydrochloride) | 130606-60-9 | >90.00% | |
An active metabolite of diltiazem | ||||
| GC52168 | Aripiprazole N,N-dioxide | 573691-13-1 | >90.00% | |
A metabolite of aripiprazole | ||||
| GC52173 | N-desmethyl-Doxylamine (succinate) | 2731375-61-2 | >90.00% | |
A metabolite of doxylamine | ||||
| GC52177 | Perphenazine Sulfoxide | 10078-25-8 | >98.00% | |
An active metabolite of perphenazine | ||||
| GC52227 | 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone | 21618-92-8 | >95.00% | |
An active metabolite of various polyphenols | ||||
| GC52324 | 3-(3-Hydroxyphenyl)propionic Acid sulfate | 86321-32-6 | >95.00% | |
A metabolite of certain phenols and glycosides | ||||
| GC52368 | DL-Sulforaphane Glutathione | 289711-21-3 | >98.00% | |
A metabolite of sulforaphane | ||||
| GC52478 | Telmisartan Acyl-β-D-Glucuronide (hydrate) | - | >95.00% | |
A major metabolite of telmisartan | ||||
| GC60124 | DCBA | 72236-23-8 | >99.50% | |
DCBA是一种驱虫剂N-N-diethyl-meta-toluamide(DEET)的代谢产物。尿液中DCBA的浓度可以评估DEET的暴露程度。 | ||||
| GC60132 | Desmethylnortriptyline | 4444-42-2 | - | |
Desmethylnortriptyline 是 Nortriptyline 的代谢产物。Nortriptyline 是三环类抗抑郁药，是 Amitriptyline 的主要活性代谢产物，用于缓解抑郁症症状。 | ||||
| GC60181 | GS-704277 | 1911579-04-8 | >95.00% | |
An intermediate alanine metabolite of remdesivir | ||||
| GC60367 | Tofacitinib metabolite-1 | 1640971-51-2 | >99.00% | |
Tofacitinib metabolite-1 是 Tofacitinib 的代谢物, JAK 抑制剂。Tofacitinib metabolite-1 可用于 Tofacitinib 的药动力学和代谢研究。 | ||||
| GC60399 | (E)-10-Hydroxynortriptyline | 47132-16-1 | >99.50% | |
An active metabolite of amitriptyline and nortriptyline | ||||
| GC60410 | (Rac)-3′-Hydroxy simvastatin | 126313-98-2 | - | |
(Rac)-3′-Hydroxysimvastatin是一种Simvastatin代谢物。Simvastatin是一种竞争性的HMG-CoA还原酶抑制剂，Ki值为0.2nM。 | ||||