P450
Cytochrome P450 are a family of heme-containing monoxygenases catalyzing the metabolism of xenobiotics in the body where P450 enzymes use O2 and two electrons provided by NAD(P)H with the help of redox partner flavoproteins and iron-sulfur proteins to catalyze the monooxygenation of a variety of substrates. Based on how electrons from NAD(P)H are delivered to the catalytic site, P450 enzymes are divided into four classes, including Class I requiring both an FAD-containing reductase and an iron sulfur redoxin, Class II requiring only an FAD/FMN-containg P450 reductase, Class III requiring no electron donor and Class IV requiring electrons directly from NAD(P)H.
P450 相关产品(439)
- GC40434(±)16-HETECAS: 128914-46-5纯度: >98.00%
A potent inhibitor of proximal tubule ATPase activity
- GC40435(±)17-HETECAS: 128914-47-6纯度: >98.00%
A potent inhibitor of proximal tubule ATPase activity
- GC40438(±)5(6)-EETCAS: 87173-80-6纯度: >95.00%
A racemic version of a CYP450 metabolite of arachidonic acid
- GC40466(±)11(12)-EETCAS: 87173-81-7纯度: >95.00%
A racemic version of a CYP450 metabolite of arachidonic acid
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC40377 | 20-HEPE | 116477-57-7 | >95.00% | |
An EPA metabolite | ||||
| GC40386 | (±)11(12)-EpETE | 504435-15-8 | >98.00% | |
Epoxygenase metabolite of EPA | ||||
| GC40388 | (±)19(20)-DiHDTE | - | >98.00% | |
An oxylipin | ||||
| GC40389 | (±)7(8)-DiHDTE | - | >98.00% | |
An oxylipin | ||||
| GC40424 | 14,15-EE-5(Z)-E | 519038-92-7 | >98.00% | |
An antagonist of EDHF-mediated vasodilation | ||||
| GC40425 | 14,15-EE-8(Z)-E | 519038-93-8 | >98.00% | |
A potent vasodilator | ||||
| GC40430 | (±)14(15)-EET | 197508-62-6 | >98.00% | |
An arachidonic acid metabolite | ||||
| GC40434 | (±)16-HETE | 128914-46-5 | >98.00% | |
A potent inhibitor of proximal tubule ATPase activity | ||||
| GC40435 | (±)17-HETE | 128914-47-6 | >98.00% | |
A potent inhibitor of proximal tubule ATPase activity | ||||
| GC40436 | (±)18-HETE | 133268-58-3 | >97.00% | |
A vasodilator of renal arterioles | ||||
| GC40437 | (±)5(6)-DiHET lactone | 213126-92-2 | >98.00% | |
A lactone form of (±)5(6)-DiHET | ||||
| GC40438 | (±)5(6)-EET | 87173-80-6 | >95.00% | |
A racemic version of a CYP450 metabolite of arachidonic acid | ||||
| GC40440 | (±)8(9)-EET | - | >98.00% | |
A racemic version of a CYP450 metabolite of arachidonic acid | ||||
| GC40443 | (±)9-HETE | 79495-85-5 | >98.00% | |
A monohydroxy fatty acid | ||||
| GC40447 | 12(R)-HETE | 82337-46-0 | >98.00% | |
An active metabolite of arachidonic acid | ||||
| GC40454 | 16(S)-HETE | 183509-23-1 | >98.00% | |
A potent inhibitor of proximal tubule ATPase activity | ||||
| GC40455 | 17(R)-HETE | 183509-24-2 | >98.00% | |
An inactive isomer of 17-HETE | ||||
| GC40456 | 17(S)-HETE | 183509-25-3 | >98.00% | |
A potent inhibitor of proximal tubule ATPase activity | ||||
| GC40457 | 19(R)-HETE | 115461-39-7 | >98.00% | |
A potent vasodilator of renal arterioles | ||||
| GC40458 | 19(S)-HETE | 115461-40-0 | >98.00% | |
Potent vasodilator of renal preglomerular vessels | ||||
| GC40464 | 9(R)-HETE | 107656-14-4 | >98.00% | |
Enantiomer of (±)9-HETE; RXRγ activator | ||||
| GC40465 | 9(S)-HETE | 107656-13-3 | >98.00% | |
A monohydroxy fatty acid and RXRγ agonist | ||||
| GC40466 | (±)11(12)-EET | 87173-81-7 | >95.00% | |
A racemic version of a CYP450 metabolite of arachidonic acid | ||||
| GC40528 | 11α-hydroxy Testosterone | 3066-12-4 | >97.00% | |
A CYP3A metabolite of testosterone | ||||