GlpBio

(±)18-HETE

目录号: GC40436纯度: >97.00%同义词: (±)18-Hydroxyeicosatetraenoic Acid
A vasodilator of renal arterioles
(±)18-HETE
Cas No.: 133268-58-3
规格价格库存数量操作
25μg¥2,248.00现货
1
50μg¥4,281.00现货
1
100μg¥8,085.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

(±)18-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid. When formed by the CYP2E1 isoform, 18-HETE is comprised 100% of the (R) isomer. 18(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, whereas 18(S)-HETE does not affect perfusion pressure. 18-HETE has negligible effects on ATPase activity. 18(R)-HETE at 1 µM completely blocks 20-HETE-induced vasoconstriction of renal arterioles.

产品文档 Product Documents

Purity:>97.00%Appearance:A solution in ethanol

化学性质Chemical Properties

CAS 号
133268-58-3
同义词
(±)18-Hydroxyeicosatetraenoic Acid
SMILES
CCC(O)CC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O
分子式
C20H32O3
分子量
320.5 g/mol
溶解性
0.1 M Na2CO3: 2 mg/ml,DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS (pH 7.2): 0.8 mg/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol