GlpBio

(±)16-HETE

目录号: GC40434纯度: >98.00%同义词: (±)16-Hydroxyeicosatetraenoic Acid
A potent inhibitor of proximal tubule ATPase activity
(±)16-HETE
Cas No.: 128914-46-5
规格价格库存数量操作
50μg¥4,281.00现货
1
100μg¥8,085.00现货
1
25μg¥2,248.00现货
1
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文献被引

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    641, 529–536 (2025)
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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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产品描述 Description

Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)16-HETE is the racemic version of a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation. The biological activity of 16-HETE is stereospecific. 16(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, however 16(S)-HETE does not affect perfusion pressure. At a concentration of 2 µM the (S)-enantiomer of 16-HETE inhibits proximal tubule ATPase activity by as much as 60%, whereas the (R)-isomer has negligible effects on ATPase activity.

产品文档 Product Documents

Purity:>98.00%Appearance:A solution in ethanol

化学性质Chemical Properties

CAS 号
128914-46-5
同义词
(±)16-Hydroxyeicosatetraenoic Acid
SMILES
CCCCC(O)/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O
分子式
C20H32O3
分子量
320.5 g/mol
溶解性
0.1 M Na2CO3: 2 mg/ml,DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS (pH 7.2): 0.8 mg/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol