P450
Cytochrome P450 are a family of heme-containing monoxygenases catalyzing the metabolism of xenobiotics in the body where P450 enzymes use O2 and two electrons provided by NAD(P)H with the help of redox partner flavoproteins and iron-sulfur proteins to catalyze the monooxygenation of a variety of substrates. Based on how electrons from NAD(P)H are delivered to the catalytic site, P450 enzymes are divided into four classes, including Class I requiring both an FAD-containing reductase and an iron sulfur redoxin, Class II requiring only an FAD/FMN-containg P450 reductase, Class III requiring no electron donor and Class IV requiring electrons directly from NAD(P)H.
P450 相关产品(439)
- GC4053420-hydroxy Prostaglandin F2αCAS: 57930-92-4纯度: >98.00%
A CYP450 ω-oxidation metabolite of PGF 2α
- GC405727-keto CholesterolCAS: 566-28-9纯度: >98.00%
7-keto Cholesterol是一种与血管疾病相关的主要氧甾醇,广泛存在于动脉粥样硬化斑块中,具有比胆固醇更强的致动脉粥样硬化作用。
- GC40841(±)11(12)-EET methyl ester纯度: >98.00%
A stable epoxide with a role in the recovery of depleted Ca 2+ pools
- GC40954(±)-N-3-BenzylnirvanolCAS: 93879-40-4纯度: >98.00%
A racemic mixture of (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC40529 | 7-hydroxy Warfarin | 17834-03-6 | - | |
A phase I metabolite of (-)-warfarin | ||||
| GC40534 | 20-hydroxy Prostaglandin F2α | 57930-92-4 | >98.00% | |
A CYP450 ω-oxidation metabolite of PGF 2α | ||||
| GC40539 | (±)12(13)-EpOME | - | >98.00% | |
The 12,13-cis epoxide form of linoleic acid | ||||
| GC40540 | (±)9(10)-EpOME | - | >98.00% | |
The 9,10-cis epoxide of linoleic acid | ||||
| GC40572 | 7-keto Cholesterol | 566-28-9 | >98.00% | |
7-keto Cholesterol是一种与血管疾病相关的主要氧甾醇,广泛存在于动脉粥样硬化斑块中,具有比胆固醇更强的致动脉粥样硬化作用。 | ||||
| GC40638 | Alclometasone Dipropionate | 66734-13-2 | >98.00% | |
A corticosteroid | ||||
| GC40801 | (±)9(10)-DiHOME | 263399-34-4 | >98.00% | |
A diol form of (±)9(10)-EpOME | ||||
| GC40802 | (±)12(13)-DiHOME | 263399-35-5 | >98.00% | |
A diol form of (±)12,13-EpOME | ||||
| GC40835 | (±)14(15)-EET methyl ester | - | >98.00% | |
An esterified version of (±)14(15)-EET | ||||
| GC40836 | (±)5(6)-EET methyl ester | - | >98.00% | |
A stable, hydrolyzable derivative of (±)5(6)-EET | ||||
| GC40838 | (±)8(9)-EET methyl ester | - | >98.00% | |
An esterified version of (±)8(9)-EET | ||||
| GC40841 | (±)11(12)-EET methyl ester | - | >98.00% | |
A stable epoxide with a role in the recovery of depleted Ca 2+ pools | ||||
| GC40888 | (±)14(15)-EpEDE methyl ester | - | >90.00% | |
A lipid soluble analog of (±)14(15)-EpEDE | ||||
| GC40905 | (±)19(20)-EpDTE | 1359721-83-7 | >98.00% | |
An oxylipin | ||||
| GC40906 | (±)7(8)-EpDTE | 1616607-36-3 | >98.00% | |
An oxylipin | ||||
| GC40954 | (±)-N-3-Benzylnirvanol | 93879-40-4 | >98.00% | |
A racemic mixture of (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol | ||||
| GC40968 | 21-hydroxy Eplerenone | 334678-67-0 | >98.00% | |
A major metabolite of eplerenone | ||||
| GC41104 | 20-carboxy Arachidonic Acid | 79551-84-1 | >98.00% | |
A metabolite of 20-HETE | ||||
| GC41116 | (±)14(15)-DiHETE | - | >98.00% | |
A metabolite of EPA | ||||
| GC41117 | (±)17(18)-DiHETE | - | >98.00% | |
An epoxygenase metabolite of EPA | ||||
| GC41119 | (±)5(6)-DiHETE | 845673-97-4 | >97.00% | |
Possible metabolite of EPA | ||||
| GC41120 | (±)8,9-DiHETE | 867350-87-6 | >98.00% | |
A major metabolite of EPA | ||||
| GC41128 | 5(S),6(R)-11-trans DiHETE | 129263-59-8 | >95.00% | |
A metabolite of LTA 4 | ||||
| GC41143 | (±)11,12-DiHETE | 867350-92-3 | >98.00% | |
An EPA metabolite | ||||
