TRP Channel
TRP Channel(瞬时受体电位离子通道)
TRP (transient receptor potential) channels are a family of cation channels that sense various external and celluar signals such as mechanical stress, temperature, cellular messengers and exogenous chemicals. It is implicated in vascular tone , neurological disorders, kidney diseases, hypomagnesemia and hypocalcemia etc.
TRP Channel 相关产品(162)
- GC43884Hyperforin (dicyclohexylammonium salt)CAS: 238074-03-8纯度: >98.00%
Hyperforin (dicyclohexylammonium salt)是一种贯叶金丝桃（ St. John's wort ）的主要活性成分，可激活瞬时受体典型6（TRPC6）通道。
- GC63244TRPV4 agonist-1 free baseCAS: 2314467-59-7纯度: >99.50%
TRPV4 agonist-1 free base是一种瞬时受体电位香草素4（TRPV4）激动剂，在hTRPV4 Ca 2+ 试验中的EC 50 值为60nM。
- GC63249Vanilloid receptor antagonist 1CAS: 871814-52-7纯度: >98.00%
Vanilloid receptor antagonist 1 是一种有效的香草酸受体 (TRPV1) 拮抗剂，详细信息请参考专利 US8349852B2 中的compound B8。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC40860 | AC1903 | 831234-13-0 | >99.50% | |
A TRPC5 inhibitor | ||||
| GC43884 | Hyperforin (dicyclohexylammonium salt) | 238074-03-8 | >98.00% | |
Hyperforin (dicyclohexylammonium salt)是一种贯叶金丝桃（ St. John's wort ）的主要活性成分，可激活瞬时受体典型6（TRPC6）通道。 | ||||
| GC44075 | Linopirdine | 105431-72-9 | >98.50% | |
A neurotransmitter release enhancer | ||||
| GC44816 | Resolvin D2 | 810668-37-2 | >95.00% | |
A product of the action of 15- and 5-LO on DHA | ||||
| GC45907 | RN-9893 (hydrochloride) | 2109450-40-8 | >98.00% | |
A TRPV4 antagonist | ||||
| GC46199 | PF-05105679 | 1398583-31-7 | >98.00% | |
A TRPM8 antagonist | ||||
| GC50058 | AMG 21629 | 939040-79-6 | - | |
Potent and selective TRPV1 antagonist | ||||
| GC50115 | ASP 7663 | 1190217-35-6 | >99.00% | |
A TRPA1 agonist | ||||
| GC50188 | CIM 0216 | 1031496-06-6 | >99.50% | |
A TRPM3 channel activator | ||||
| GC50261 | A 425619 | 581809-67-8 | - | |
Potent TRPV1 antagonist | ||||
| GC50268 | M 084 hydrochloride | - | - | |
TRPC4/5 channel blocker; antidepressant and anxiolytic | ||||
| GC50475 | AM 12 | 2387510-84-9 | - | |
TRPC5 inhibitor | ||||
| GC50557 | CBA | 351424-20-9 | >98.00% | |
A TRPM4 inhibitor | ||||
| GC50590 | TRPC6-PAM-C20 | 667427-75-0 | - | |
TRPC6-PAM-C20 是 TRPC6 通道的选择性正变构调节剂 (PAM)。 | ||||
| GC50617 | BTD | 896684-04-1 | - | |
Selective TRPC5 activator | ||||
| GC50640 | OptoBI-1 | 2415272-11-4 | - | |
OptoBI-1 是一种光致变色 TRPC3 激动剂，可作为一种光药理学工具来控制神经元放电。 | ||||
| GC50641 | IA-Alkyne | 930800-38-7 | >99.00% | |
IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) 是一种 TRP 通道 (TRPC) 激动剂，具有研究呼吸道感染的潜力。 | ||||
| GC50667 | SET 2 | 2313525-20-9 | >98.00% | |
TRPV2 (transient receptor potential vanilloid type 2) antagonist (IC50 = 0 | ||||
| GC50670 | D-GsMTx4 | - | >98.00% | |
TRPC1/6 and Piezo2 inhibitor | ||||
| GC60542 | 8-Gingerol | 23513-08-8 | >99.50% / >99.00% | |
A natural TRPV1 agonist | ||||
| GC61792 | Cyclic ADP-ribose ammonium | - | >99.00% | |
An endogenous Ca 2+ mobilizer | ||||
| GC62179 | Cyclic ADP-ribose | 119340-53-3 | >95.00% | |
An endogenous Ca 2+ mobilizer | ||||
| GC63244 | TRPV4 agonist-1 free base | 2314467-59-7 | >99.50% | |
TRPV4 agonist-1 free base是一种瞬时受体电位香草素4（TRPV4）激动剂，在hTRPV4 Ca 2+ 试验中的EC 50 值为60nM。 | ||||
| GC63249 | Vanilloid receptor antagonist 1 | 871814-52-7 | >98.00% | |
Vanilloid receptor antagonist 1 是一种有效的香草酸受体 (TRPV1) 拮抗剂，详细信息请参考专利 US8349852B2 中的compound B8。 | ||||