Reactive Oxygen Species
Reactive Oxygen Species(活性氧)
Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion.
ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.
Reactive Oxygen Species 相关产品(453)
- GC49422PAR2 (1-6) amide (human) (trifluoroacetate salt)CAS: 2379569-17-0纯度: >95.00%
A peptide agonist of PAR2
- GC49436L-3-n-ButylphthalideCAS: 3413-15-8纯度: >99.00%
A phthalide with antiplatelet and neuroprotective activities
- GC49855Harmalol (hydrochloride hydrate)CAS: 6028-00-8纯度: >98.00%
A β-carboline alkaloid and an active metabolite of harmaline
- GC52073N-formyl-2-AminophenolCAS: 2843-27-8纯度: >98.00%
A bacterial secondary metabolite with antioxidant activity
- GC52081ChamazuleneCAS: 529-05-5纯度: >98.00%
A terpene with anti-inflammatory and antioxidant activities
- GC52190Imidazole Ketone ErastinCAS: 1801530-11-9纯度: >98.00%
Imidazole Ketone Erastin是一种有效的、代谢稳定的系统xc- 抑制剂和铁凋亡诱导剂。
- GC522275-(3',4'-Dihydroxyphenyl)-γ-ValerolactoneCAS: 21618-92-8纯度: >95.00%
An active metabolite of various polyphenols
- GC52283L-Cysteine-15N-d3CAS: 1795787-05-1纯度: >99.00%
An internal standard for the quantification of L-cysteine
- GC523243-(3-Hydroxyphenyl)propionic Acid sulfateCAS: 86321-32-6纯度: >95.00%
A metabolite of certain phenols and glycosides
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC49422 | PAR2 (1-6) amide (human) (trifluoroacetate salt) | 2379569-17-0 | >95.00% | |
A peptide agonist of PAR2 | ||||
| GC49426 | Taurine-d4 | 342611-14-7 | >99.00% | |
An internal standard for the quantification of taurine | ||||
| GC49436 | L-3-n-Butylphthalide | 3413-15-8 | >99.00% | |
A phthalide with antiplatelet and neuroprotective activities | ||||
| GC49486 | Meglutol-d3 | 59060-36-5 | >99.00% | |
An internal standard for the quantification of meglutol | ||||
| GC49500 | Stobadine | 85202-17-1 | >98.00% | |
A pyridoindole antioxidant | ||||
| GC49521 | MHY553 | 6265-56-1 | >98.00% | |
An agonist of PPARα | ||||
| GC49557 | Cu-GTSM | 68341-14-0 | >95.00% | |
A copper-containing compound with diverse biological activities | ||||
| GC49560 | L6H21 | 24533-47-9 | >98.00% | |
An inhibitor of the MD-2 and TLR4 interaction | ||||
| GC49597 | Leukotriene B4-d5 | - | >99.00% | |
An internal standard for the quantification of LTB 4 | ||||
| GC49708 | Biliverdin (technical grade) | 114-25-0 | >70.00% | |
A bile pigment | ||||
| GC49790 | Reuterin | 2134-29-4 | >98.00% | |
A bacterial glycerol metabolite with antibacterial activity | ||||
| GC49849 | 3-Aminosalicylic Acid | 570-23-0 | >98.00% | |
A salicylic acid derivative | ||||
| GC49855 | Harmalol (hydrochloride hydrate) | 6028-00-8 | >98.00% | |
A β-carboline alkaloid and an active metabolite of harmaline | ||||
| GC49864 | 6-Methylpterin | 708-75-8 | >98.00% | |
A derivative of folic acid | ||||
| GC49868 | D-α-Tocopheryl Quinone | 7559-04-8 | >98.00% | |
An oxidative metabolite of vitamin E | ||||
| GC52007 | N-hydroxylamine Dapsone | 32695-27-5 | >98.00% | |
An active metabolite of dapsone | ||||
| GC52027 | Isolariciresinol | 548-29-8 | >98.00% | |
A lignan with diverse biological activities | ||||
| GC52073 | N-formyl-2-Aminophenol | 2843-27-8 | >98.00% | |
A bacterial secondary metabolite with antioxidant activity | ||||
| GC52081 | Chamazulene | 529-05-5 | >98.00% | |
A terpene with anti-inflammatory and antioxidant activities | ||||
| GC52164 | Cu-ATSP | 68341-12-8 | >98.00% | |
A copper-containing bis(thiosemicarbazone) complex | ||||
| GC52190 | Imidazole Ketone Erastin | 1801530-11-9 | >98.00% | |
Imidazole Ketone Erastin是一种有效的、代谢稳定的系统xc- 抑制剂和铁凋亡诱导剂。 | ||||
| GC52227 | 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone | 21618-92-8 | >95.00% | |
An active metabolite of various polyphenols | ||||
| GC52283 | L-Cysteine-15N-d3 | 1795787-05-1 | >99.00% | |
An internal standard for the quantification of L-cysteine | ||||
| GC52324 | 3-(3-Hydroxyphenyl)propionic Acid sulfate | 86321-32-6 | >95.00% | |
A metabolite of certain phenols and glycosides | ||||