6-Methylpterin is a derivative of the essential B vitamin folic acid .1 It generates singlet oxygen and hydrogen peroxide when exposed to photoirradiation in cell-free assays.2 6-Methylpterin has been used as an internal standard for the detection of pterins in urine.3
1.Tsyupka, D.V., Mordovina, E.A., Sindeeva, O.A., et al.High-fluorescent product of folic acid photodegradation: Optical properties and cell effectJ. Photochem. Photobiol. A Chem.407113045(2021) 2.Cabrerizo, F.M., Lorente, C., Vignoni, M., et al.Photochemical behavior of 6-methylpterin in aqueous solutions: Generation of reactive oxygen speciesPhotochem. Photobiol.81(4)793-801(2005) 3.GirÓn, A.J., MartÍn-Tornero, E., SÁnchez, M.C.H., et al.A simple HPLC-ESI-MS method for the direct determination of ten pteridinic biomarkers in human urineTalanta101465-472(2012)