GlpBio

PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)

目录号: GC44750纯度: >98.00%同义词: DPPI3,4,5P3, Phosphatidylinositol3,4,5triphosphate C16
A synthetic analog of natural PtdIns
PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl) (sodium salt)
Cas No.: 1628353-02-5
规格价格库存数量操作
1mg¥5,544.00现货
1
100μg¥724.00现货
1
500μg¥3,172.00现货
1
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文献被引

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    641, 529–536 (2025)
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    610, 366–372 (2022)
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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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产品描述 Description

The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Centuarin α and the Akt-family of GTPase activating proteins are examples of PtdIns-(3,4,5)-P3-binding proteins. Protein-binding to PtdIns-(3,4,5)-P3 is important for cytoskeletal rearrangements and membrane trafficking. PtdIns-(3,4,5)-P3 is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. For further reading on inositol phospholipids, see also references and .

产品文档 Product Documents

Purity:>98.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
1628353-02-5
同义词
DPPI3,4,5P3, Phosphatidylinositol3,4,5triphosphate C16
SMILES
[O-]P(OC[C@H](OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)(O[C@@H]1[C@H](O)[C@H](OP([O-])(O)=O)[C@@H](OP([O-])(O)=O)[C@H](OP([O-])(O)=O)[C@H]1O)=O.[Na+].[Na+].[Na+].[Na+]
分子式
C41H78O22P4•4Na
分子量
1138.9 g/mol
溶解性
CHCl3:CH3OH:Water (2.5:3:1): 3.8 mg/ml,PBS (pH 7.2): 10 mg/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol