关于 "Cancer stem cell" 的结果29+ 个结果
- NFAT Inhibitor (cell-permeable) (trifluoroacetate salt)
A cell-permeable form of NFAT inhibitor
- PD-1/PD-L1 Inhibitor 3 (trifluoroacetate salt)
A PD-1/PD-L1 interaction inhibitor
Immunology/Inflammation - PD-1/PD-L1 Inhibitor N11
PD-1/PD-L1 inhibitor N11 is an inhibitor of the protein-protein interaction between programmed cell death protein 1 (PD-1) and PD-1 ligand (PD-L1; IC50 = 6.3 nM).
Immunology/Inflammation - HPFCAS: 359010-69-8
A cell permeable, fluorescent dye for detection of highly reactive oxygen species
- CH 223191CAS: 301326-22-7
CH 223191是一种有效且特异性的芳烃受体（AhR）拮抗剂，可抑制TCDD介导的AhR核转位和DNA结合，并抑制TCDD诱导的荧光素酶活性，IC50为0.03 μM。
- SP-8356CAS: 1454885-45-0
SP-8356, an anti-inflammatory synthetic verbenone derivative, is a CD147 inhibitor with respect to its regulation of breast cancer cell behavior and cancer progression.
- TributyrinCAS: 60-01-5
Glycerol tributyrate (Tributyrin) is a triglyceride that may inhibit cell growth and induce cell differentiation.
- RA-9CAS: 919091-63-7
RA-9 is a cell-permeable, potent and selective inhibitor of proteasome-associated deubiquitinating enzymes (DUBs) with favorable toxicity profile and anticancer activity. RA-9 selectively induces apoptosis in ovarian cancer cell lines.
- PicrocrocinCAS: 138-55-6
Picrocrocin, the chemical most responsible for the bitter taste of saffron, is isolated from saffron and inhibits proliferation of cancer cells.
- ZINC05007751CAS: 591239-68-8
ZINC05007751 is a potent NIMA-related kinase NEK6 inhibitor with an IC50 of 3.4 μM, shows antiproliferative activity against a panel of human cancer cell lines and displays a synergistic effect with Cisplatin and Paclitaxel in a BRCA2 mutated ovarian cancer cell line. DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation.
- N6F11CAS: 851398-76-0
N6F11 is a novel, selective and potent inducer of iron death with anticancer and antitumour activity that promotes GPX4 degradation by binding to TRIM25 in cancer cells.
- Triglycidyl isocyanurateCAS: 2451-62-9
Triglycidyl Isocyanurate (Teroxirone, Tris(2,3-epoxypropyl) Isocyanurate, TGI, TGIC) is a triazene triepoxide with antineoplastic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl Isocyanurate alkylates and cross-links DNA, thereby inhibiting DNA replication. Triglycidyl Isocyanurate is also used in various polyester powder coatings in the metal finishing industry.
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC49723 | SenTraGor™ Cell Senescence Reagent | 2171036-89-6 | Cancer Biology | ||
A cellular senescence detection reagent | |||||
| GC50243 | NFAT inhibitor, Cell Permeable | 592517-80-1 | Interleukin Related | ||
A cell-permeable form of NFAT inhibitor | |||||
| GC52384 | NFAT Inhibitor (cell-permeable) (trifluoroacetate salt) | - | Bone Growth & Remodeling | ||
A cell-permeable form of NFAT inhibitor | |||||
| GC52425 | PD-1/PD-L1 Inhibitor 3 (trifluoroacetate salt) | - | Immunology/Inflammation | ||
A PD-1/PD-L1 interaction inhibitor | |||||
| GC91776 | PD-1/PD-L1 Inhibitor N11 | - | Immunology/Inflammation | ||
PD-1/PD-L1 inhibitor N11 is an inhibitor of the protein-protein interaction between programmed cell death protein 1 (PD-1) and PD-1 ligand (PD-L1; IC50 = 6.3 nM). | |||||
| GC14731 | MTT | 298-93-1 | Apoptosis | ||
A cell-permeable and positively charged tetrazolium dye | |||||
| GC43870 | HPF | 359010-69-8 | Reactive Oxygen Species | ||
A cell permeable, fluorescent dye for detection of highly reactive oxygen species | |||||
| GC49914 | Pt(II)-NHC Complex 2C | - | Immunology/Inflammation | ||
An inducer of immunogenic cancer cell death | |||||
| GC16220 | CH 223191 | 301326-22-7 | Aryl Hydrocarbon Receptor | ||
CH 223191是一种有效且特异性的芳烃受体（AhR）拮抗剂，可抑制TCDD介导的AhR核转位和DNA结合，并抑制TCDD诱导的荧光素酶活性，IC50为0.03 μM。 | |||||
| GC44238 | Mn(III)TBAP | 55266-18-7 | NF-κB | ||
A cell-permeable SOD mimic | |||||
| GC61286 | SP-8356 | 1454885-45-0 | Cell Migration & Metastasis | ||
SP-8356, an anti-inflammatory synthetic verbenone derivative, is a CD147 inhibitor with respect to its regulation of breast cancer cell behavior and cancer progression. | |||||
| GC62676 | TJ191 | 1522415-97-9 | Apoptosis | ||
TJ191 is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells. | |||||
| GC12040 | L-Kynurenine | 2922-83-0 | Endogenous Metabolite | ||
L-Kynurenine是L-色氨酸的代谢物，也是一种芳香烃受体 (aryl hydrocarbon receptor; AhR) 激动剂。 | |||||
| GC61349 | Tributyrin | 60-01-5 | Apoptosis | ||
Glycerol tributyrate (Tributyrin) is a triglyceride that may inhibit cell growth and induce cell differentiation. | |||||
| GC43105 | C8 Ceramide (d18:1.8:0) | 74713-59-0 | PKC | ||
A cell-permeable ceramide analog | |||||
| GC49027 | Hexamethylene bisacetamide | 3073-59-4 | Cancer stem cell | ||
A tumor cell-differentiating agent | |||||
| GC60317 | RA-9 | 919091-63-7 | Deubiquitinase | ||
RA-9 is a cell-permeable, potent and selective inhibitor of proteasome-associated deubiquitinating enzymes (DUBs) with favorable toxicity profile and anticancer activity. RA-9 selectively induces apoptosis in ovarian cancer cell lines. | |||||
| GC60288 | Picrocrocin | 138-55-6 | Apoptosis | ||
Picrocrocin, the chemical most responsible for the bitter taste of saffron, is isolated from saffron and inhibits proliferation of cancer cells. | |||||
| GC63626 | ZINC05007751 | 591239-68-8 | Others | ||
ZINC05007751 is a potent NIMA-related kinase NEK6 inhibitor with an IC50 of 3.4 μM, shows antiproliferative activity against a panel of human cancer cell lines and displays a synergistic effect with Cisplatin and Paclitaxel in a BRCA2 mutated ovarian cancer cell line. DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation. | |||||
| GC91380 | N6F11 | 851398-76-0 | Ubiquitination/ Proteasome | ||
N6F11 is a novel, selective and potent inducer of iron death with anticancer and antitumour activity that promotes GPX4 degradation by binding to TRIM25 in cancer cells. | |||||
| GC17043 | StemRegenin 1 (SR1) | 1227633-49-9 | Aryl Hydrocarbon Receptor | ||
StemRegenin 1 (SR1)是一种强效芳香烃受体（AhR）拮抗剂（IC50 = 127nM）。 | |||||
| GC14847 | Psoralidin | 18642-23-4 | Reactive Oxygen Species | ||
A furanocoumarin with anti-cancer activity | |||||
| GC12628 | ITE | 448906-42-1 | Aryl Hydrocarbon Receptor | ||
ITE是一种有效的免疫抑制性内源性芳香烃受体（AhR）激动剂，与AhR结合的Ki值为3nM。 | |||||
| GC61352 | Triglycidyl isocyanurate | 2451-62-9 | p53 | ||
Triglycidyl Isocyanurate (Teroxirone, Tris(2,3-epoxypropyl) Isocyanurate, TGI, TGIC) is a triazene triepoxide with antineoplastic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl Isocyanurate alkylates and cross-links DNA, thereby inhibiting DNA replication. Triglycidyl Isocyanurate is also used in various polyester powder coatings in the metal finishing industry. | |||||