GlpBio

Fungal

Fungal(真菌)

An antifungal agent is a drug that selectively eliminates fungal pathogens from a host with minimal toxicity to the host. Classes: 1. Polyene Antifungal Drugs: Amphotericin, nystatin, and pimaricin interact with sterols in the cell membrane (ergosterol in fungi, cholesterol in humans) to form channels through which small molecules leak from the inside of the fungal cell to the outside. 2. Azole Antifungal Drugs: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. 3. Allylamine and Morpholine Antifungal Drugs: lylamines (naftifine, terbinafine) inhibit ergosterol biosynthesis at the level of squalene epoxidase. The morpholine drug, amorolfine, inhibits the same pathway at a later step. 4. Antimetabolite Antifungal Drugs: 5-Fluorocytosine acts as an inhibitor of both DNA and RNA synthesis via the intracytoplasmic conversion of 5-fluorocytosine to 5-fluorouracil.

Fungal 相关产品(356)

  • GC25778 structure
    GC25778Potassium 1-Naphthaleneacetate
    CAS: 15165-79-4

    Potassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens.

  • GC30216 structure
    GC3021610-Undecenoic acid (Undecylenic acid)
    CAS: 112-38-9
    纯度: >98.00%

    10-Undecenoic acid, a natural or synthetic fungistatic fatty acid, is used for the preparation of active pharmaceutical ingredients, cosmetics, perfumes, antidandruff shampoos and antimicrobial powders.

  • GC30484 structure
    GC30484Methasulfocarb
    CAS: 66952-49-6

    Methasulfocarb是一种杀真菌剂。

  • GC30646 structure
    GC30646Skatole(3-Methylindole)
    CAS: 83-34-1
    纯度: >99.50%

    Skatole (3-methylindole, Scatole) is a mildly toxic white crystalline organic compound that occurs naturally in feces. It has a fairly broad bacteriostatic effect.

  • GC30800 structure
    GC3080010-Undecenoic acid zinc salt (Zinc undecylenate)
    CAS: 557-08-4
    纯度: >98.00%

    Zinc Undecylenate (Zinc diundec-10-enoate, Zinc 10-undecenoate) is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions.

  • GC30830 structure
    GC30830Magainin 2
    CAS: 108433-95-0
    纯度: >99.00%

    Magainin2是在非洲爪蟾皮肤中发现的抗微生物多肽。

  • GC30867 structure
    GC30867Myclobutanil
    CAS: 88671-89-0
    纯度: >99.00%

    An Analytical Reference Standard

  • GC30960 structure
    GC30960Caerulomycin A (Cerulomycin)
    CAS: 21802-37-9
    纯度: >98.00%

    A fungal metabolite with antifungal and immunosuppressant activities

  • GC32041 structure
    GC32041Triphala
    CAS: 857906-76-4

    Triphala是阿育吠陀的多草药配方，Triphala由三种草本植物Terminaliachebula，Terminaliabellerica，和Phyllanthusemblica组成。Triphala抑制NF-κB活化。Triphala发挥抗真菌(antifungal)作用。具有抗脂肪形成，抗炎，抗肿瘤效果。

  • GC32078 structure
    GC32078Clioquinol (Iodochlorhydroxyquin)
    CAS: 130-26-7
    纯度: >98.50%

    A metal-chelating antimicrobial agent

  • GC32111 structure
    GC32111Imazalil (Enilconazole)
    CAS: 35554-44-0
    纯度: >99.50%

    An imidazole fungicide

  • GC32116 structure
    GC32116Ravuconazole (BMS-207147)
    CAS: 182760-06-1
    纯度: >99.50%

    A triazole antifungal

  • GC32131 structure
    GC32131Terconazole (R42470)
    CAS: 67915-31-5
    纯度: >99.00%

    A triazole antifungal

  • GC32147 structure
    GC32147Carbendazim
    CAS: 10605-21-7
    纯度: >99.50%

    A degradation product and active ingredient of benomyl

  • GC32150 structure
    GC32150Thifluzamide
    CAS: 130000-40-7
    纯度: >98.00%

    Thifluzamide是一种强效杀菌剂。

  • GC32160 structure
    GC32160Tebuconazole
    CAS: 107534-96-3
    纯度: >98.00%

    A triazole fungicide

  • GC32184 structure
    GC32184Cloxiquine (5-Chloro-8-quinolinol)
    CAS: 130-16-5
    纯度: >98.00%

    Cloxiquine (5-Chloro-8-quinolinol, Dermofungin) is an antibacterial, antifungal, antiaging and antituberculosis drug.

  • GC32203 structure
    GC32203Piroctone olamine (Piroctone ethanolamine)
    CAS: 68890-66-4
    纯度: >98.00%

    Piroctone Olamine (piroctone ethanolamine) is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff,fungal infections.

  • GC32219 structure
    GC32219Antifungal agent 1
    CAS: 1265166-14-0
    纯度: >98.00%

    Antifungalagent1是一种有效的抗真菌剂。

  • GC32221 structure
    GC32221Sulbentine (Dibenzthione)
    CAS: 350-12-9
    纯度: >98.00%

    Sulbentine (Dibenzthione) (Dibenzthione) 是一种唑类抗真菌剂，具有抑菌和杀真菌活性。

  • GC32244 structure
    GC32244Micafungin (FK463)
    CAS: 235114-32-6
    纯度: >98.00%

    Micafungin Sodium (FK463, Mycamine) is an inhibitor of 1, 3-beta-D-glucan synthesis, used as an antifungal drug.

  • GC32248 structure
    GC32248Propoxur
    CAS: 114-26-1
    纯度: >99.00%

    A carbamate insecticide

  • GC32268 structure
    GC32268Stilbamidine (Ba 2652)
    CAS: 122-06-5

    Stilbamidine (Ba 2652) 是一种衍生自芪的二脒化合物，主要以其结晶羟乙基磺酸盐的形式用于治疗各种真菌感染。

  • GC32275 structure
    GC32275Econazole ((±)-Econazol)
    CAS: 27220-47-9
    纯度: >99.00%

    Econazole is a broad spectrum antimycotic with some action against Gram positive bacteria.