Autophagy(自噬)

Autophagy is a catabolic process which degrades and recycles long-lived proteins and cytoplasmic organelles through lysosome. It plays an important role in growth regulation and maintenance of homeostasis.

Products for Autophagy

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Cat.No. 产品名称 Information
GC13559 Cilengitide

西仑吉肽; EMD 121974
An integrin αVβ3 receptor antagonist
GC61520 Cilengitide TFA

EMD 121974 TFA
An integrin αVβ3 receptor antagonist
GC18212 Cilofexor

GS-9674
An FXR ligand
GC15890 Cilostazol

西洛他唑; OPC 13013
A PDE3A inhibitor
GN10189 Cinobufagin

华蟾蜍精; Cinobufagine
A cardiotonic steroid with diverse biological activities
GC12226 Cisatracurium Besylate

顺苯磺酸阿曲库铵; 51W89
A competitive antagonist of nAChRs and non-depolarizing muscle relaxant
GC14035 Citalopram hydrobromide

氢溴酸西酞普兰; (±)-Citalopram hydrobromide; Lu 10-171
A selective serotonin reuptake inhibitor
GC16754 Clarithromycin

克拉霉素
A macrolide antibiotic
GC14892 Clemastine Fumarate

富马酸氯马斯汀; HS-592 fumarate; Meclastine fumarate
A histamine H₁ receptor antagonist
GC71637 Clemastine-d5 fumarate Clemastine-d5 fumarate是氘标记的富马酸氯马斯汀。
GC64524 Clematichinenoside AR

灵仙新苷

Clematichinenoside AR 是一种可以从中药 Clematis chinensis 中提取的有效成分，对包括动脉粥样硬化等多种疾病显示出有效的生物学活性。
GC15810 Clinofibrate

克利贝特,S-8527
A hypolipidemic agent
GC32078 Clioquinol (Iodochlorhydroxyquin)

氯碘羟喹,Iodochlorhydroxyquin

A metal-chelating antimicrobial agent
GC73224 CLK1-IN-3 CLK1-IN-3（化合物10ad）是一种有效的选择性Clk1抑制剂，IC50为5 nM，对Dyrk1A的选择性超过300倍。
GC15219 Clofarabine

氯法拉滨
A ribonucleotide reductase and DNA polymerase-α inhibitor
GC16804 Clotrimazole

克霉唑
An imidazole antifungal
GC13261 Colchicine

秋水仙碱
Colchicine（秋水仙碱）是一种可口服的生物碱，通过抑制β-微管蛋白聚合成微管来破坏细胞骨架功能，Colchicine抑制微管的IC₅₀为3 nM。
GC16332 Colistin Sulfate

硫酸粘杆菌素; Polymyxin E sulfate
An antibiotic
GC17519 Concanamycin A

刀豆素A; Antibiotic X 4357B; Folimycin; X 4357B
Concanamycin A 是液泡型 ATP 酶 (V-ATPase) 的特异性抑制剂，IC50 值为 10 nM 。
GN10810 Cordycepin

虫草素; 3'-Deoxyadenosine
Cordycepin（3’-deoxyadenosine; 虫草素）是一种核苷类似物，抑制聚腺苷酸化。
GN10015 Corosolic Acid

科罗索酸; Colosolic acid
A triterpenoid with diverse biological activities
GC32959 Corynoxine

柯诺辛
An indole alkaloid
GC52477 Corynoxine (hydrochloride) An indole alkaloid
GC32826 Corynoxine B

柯诺辛碱 B
柯诺辛B(CorynoxineB)是吲哚生物碱天然化合物，一个beclin-1-dependent自噬诱导剂。
GC43321 CPTH6 (hydrobromide) A Gcn5 and pCAF HAT inhibitor
GC14906 Crenolanib (CP-868596)

[1-[2-[5-(3-甲基氧杂环丁烷-3-基甲氧基)苯并咪唑-1-基]喹啉-8-基]哌啶-4-基]胺,CP-868596;CP 868596;CP868596
An inhibitor of PDGFRα/β and FLT3
GC30360 Cresol (Cresol mixture of isomers) Cresol是一种有机化合物，是芳香族有机化合物广泛存在的天然及合成基团。
GC12616 Crizotinib hydrochloride

克里唑替尼盐酸,PF-02341066 hydrochloride
Crizotinib hydrochloride (PF-02341066 hydrochloride) 是一种具有口服生物利用度、选择性和 ATP 竞争性的双重 ALK 和 c-Met 抑制剂，IC50 分别为 20 和 8 nM。 Crizotinib hydrochloride (PF-02341066 hydrochloride) 在基于细胞的试验中抑制 NPM-ALK 的酪氨酸磷酸化和 c-Met 的酪氨酸磷酸化，IC50 分别为 24 和 11 nM。它也是一种 ROS 原癌基因 1 (ROS1) 抑制剂。 Crizotinib hydrochloride (PF-02341066 hydrochloride) 具有有效的肿瘤生长抑制作用。
GN10501 Cryptotanshinone

隐丹参酮; Cryptotanshinon; Tanshinone c
Cryptotanshinone是从丹参（Salvia miltiorrhiza Bunge）的根中提取的天然化合物，具有抗肿瘤活性，能够抑制信号转导及转录激活蛋白3（STAT3），IC₅₀值为4.6μM。
GN10535 Cucurbitacin B

葫芦素 B

A natural triterpene
GN10526 Cucurbitacin E

葫芦素 E; α-Elaterin; α-Elaterine
A natural triterpene
GC73383 CUR5g CUR5g是一种强效的自噬抑制剂。
GC14787 Curcumin

姜黄素; Diferuloylmethane; Natural Yellow 3; Turmeric yellow

A yellow pigment with diverse biological activities
GC40226 Curcumin-d6

(1E,4Z,6E)-5-羟基-1,7-二[4-羟基-3-(甲氧基-D3)苯基]-1,4,6-庚三烯-3-酮,Diferuloylmethane-d6; Natural Yellow 3-d6; Turmeric yellow-d6
An internal standard for the quantification of curcumin
GC14495 CX 546

苯并二氧六环-6-(1-哌啶基)甲酰胺
CX 546 是第一代选择性苯甲酰胺型正 AMPAR 调节剂。
GC13037 CX-4945 (Silmitasertib)

CX 4945;CX4945
A potent, orally bioavailable CK2 inhibitor
GC11325 CX-4945 sodium salt

CX-4945 sodium salt
A potent, orally bioavailable CK2 inhibitor
GC17795 Cyclocytidine HCl

盐酸环胞苷,Cyclocytidine hydrochloride; Cyclo-CMP hydrochloride; Cyclo-C
A prodrug form of cytarabine
GC17198 Cycloheximide

Naramycin A; Actidione; 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide
环己酰亚胺是一种抗生素，它在翻译水平上抑制蛋白质合成，仅对真核细胞的细胞质（80s）核糖体起作用。
GC38419 Cyclovirobuxine D

黄杨碱
An alkaloid with diverse biological activities
GC43354 Cysmethynil

Icmt Inhibitor
An inhibitor of protein prenylation
GC33779 Cysteamine (β-Mercaptoethylamine)

巯基乙胺
2-Aminoethanethiol (cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Thioethanolamine, Mercaptamine) is a radiation-protective agent that oxidizes in air to form cystamine.
GC13502 Cysteamine HCl

半胱胺盐酸盐; 2-Aminoethanethiol hydrochloride; 2-Mercaptoethylamine hydrochloride
A radioprotective aminothiol
GC17050 CYT387

莫洛替尼,Cyt-387,MOMELOTINIB,CYT 387,CYT 11387
A potent inhibitor of JAK1 and JAK2
GC16468 CYT387 sulfate salt

N-(氰基甲基)-4-[2-[[4-(4-吗啉基)苯基]氨基]-4-嘧啶基]苯甲酰胺硫酸盐(1:2),CYT-387 sulfate;CYT 387 sulfate
A potent inhibitor of JAK1 and JAK2
GC13070 Cytarabine

阿糖胞苷; Cytosine β-D-arabinofuranoside; Cytosine Arabinoside; Ara-C
Cytarabine（Ara-C）是一种胞嘧啶类似物，主要抑制DNA聚合酶的功能来阻断DNA合成。
GC14961 Cytarabine hydrochloride

盐酸阿糖胞苷; Cytosine β-D-arabinofuranoside hydrochloride; Cytosine Arabinoside hydrochloride; Ara-C hydrochloride
A nucleoside analog and prodrug form of ara-CTP
GC43359 Cytochalasin E

细胞松弛素E
Inhibitor of actin polymerization
GC40792 D-threo Sphinganine (d18:0)

D-苏式二氢鞘氨醇
A bioactive sphingolipid
GC13202 D4476

4-[4-(2,3-二氢-1,4-苯并二氧杂环己-6-基)-5-(2-吡啶基)-1H-咪唑-2-基]苯甲酰胺,Casein Kinase I Inhibitor;D 4476;D-4476
Inhibitor of CK1 and ALK5