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Home >> Signaling Pathways >> Ubiquitination/ Proteasome >> Autophagy

Autophagy(自噬)

Autophagy is a catabolic process which degrades and recycles long-lived proteins and cytoplasmic organelles through lysosome. It plays an important role in growth regulation and maintenance of homeostasis.

Products for  Autophagy

  1. Cat.No. 产品名称 Information
  2. GC16966 VER 155008

    adenosine-derived inhibitor, VER155008, VER-155008

     An Hsp70 inhibitor
  3. GC14482 Verteporfin

    维替泊芬; CL 318952

     维替泊芬是一种有效的 PD-L1 表达抑制剂，用于治疗年龄相关性黄斑变性、鲜红斑痣和癌症。
  4. GC12286 Vinblastine sulfate

    硫酸长春碱; Vincaleukoblastine sulfate salt

     Vinblastine sulfate是一种细胞毒性生物碱。
  5. GN10299 Vinorelbine

    长春瑞宾

     An inhibitor of microtubule polymerization
  6. GC14806 Vinorelbine ditartrate

    酒石酸长春瑞滨; KW-2307; Nor-5'-anhydrovinblastine ditartrate

     An inhibitor of microtubule polymerization
  7. GC73603 VISTA-IN-2 VISTA-IN-2（化合物1）是t细胞活化v域Ig抑制因子（VISTA）的抑制剂。
  8. GC11007 VO-Ohpic trihydrate

    VO-OHPIC三水合物,VO-Ohpic;VO Ohpic

     A specific inhibitor of PTEN
  9. GC17390 Vorinostat (SAHA, MK0683)

    伏立诺他; SAHA; Suberoylanilide hydroxamic acid

    An HDAC inhibitor
  10. GC10436 VPS34-IN1

    Vacuolar Protein Sorting 34 Inhibitor 1, Vps34 Inhibitor 1

     A potent and selective inhibitor of Vps34
  11. GC14920 VX-661

    VX-661

     An investigational compound that promotes the maturation of delta F508 CFTR
  12. GC11549 VX-680 (MK-0457,Tozasertib)

    陶扎色替,VX 680; MK-0457

     An Aurora kinase inhibitor that regulates mitosis
  13. GC17508 VX-702

    6-[(氨基羰基)(2,6-二氟苯基)氨基]-2-(2,4-二氟苯基)-3-吡啶甲酰胺

     An inhibitor of p38 MAP kinases
  14. GC12926 VX-745

    VX-745

     A p38α MAPK inhibitor
  15. GC15455 VX-809

    鲁玛卡托; VX-809; VRT 826809

     A F508del-CFTR corrector
  16. GN10017 Wogonin

    汉黄芩素

     A flavonoid with anti-inflammatory and antitumor activities
  17. GN10097 Wogonoside

    汉黄芩苷

     A flavonoid with anti-inflammatory and anticancer activities
  18. GC12338 Wortmannin

    渥曼青霉素; SL-2052; KY-12420

     渥曼青霉素是一种高效的 PI3 激酶特异性直接抑制剂，最初源自真菌 (1,2)。
  19. GC10970 WP1130

    WP 1130; WP-1130

     A deubiquitinase inhibitor
  20. GC34862 WYC-209

    4,5-二(羟甲基)-2-苯基-1H-咪唑

     WYC-209是一种合成类视黄醇，能抑制恶性小鼠黑色素瘤肿瘤再生细胞(TRC)的增殖，IC50值为0.19μM。WYC-209主要细胞靶点是维甲酸受体(RARs)。
  21. GC10662 WYE-354

    4-[6-[4-[(甲氧羰基)氨基]苯基]-4-(4-吗啉基)-1H-吡唑并[3,4-D]嘧啶-1-基]-1-哌啶羧酸甲酯

     Potent inhibitor of mTOR in both mTORC1 and mTORC2
  22. GC12391 Xanthohumol

    黄腐醇

    A natural prenylated chalcone
  23. GC10789 XCT790

    3-[4-[[2,4-二(三氟甲基)苄基]氧基]-3-甲氧基苯基]-2-氰基-N-(5-三氟甲基-[1,3,4]噻二唑-2-基)丙烯酰胺

     A selective inverse agonist of ERRα
  24. GC72701 XIE62-1004-A XIE62-1004-A是p62-LC3相互作用的诱导剂。
  25. GC10760 XL335

    3-(3,4-二氟苯甲酰基)-1,2,3,6-四氢-1,1-二甲基氮杂卓[4,5-B]吲哚-5-甲酸1-甲基乙基酯,FXR-450; XL335; WAY-362450

     A potent and selective FXR agonist
  26. GC34330 XRK3F2 XRK3F2 is an inhibitor of the p62-ZZ domain that blunts MM-induced Runx2 suppression in vitro, and induces new bone formation and remodeling in the presence of tumor in vivo.
  27. GN10382 Xylitol

    木糖醇; Xylite

     木糖醇是一种化学物质，归类为多元醇或糖醇。
  28. GC68146 Xylitol-5-13C

    Xylite-5-13C

     Xylitol-5-13C 是 13C 标记的 Xylitol。 Xylitol可被分类为多元醇和糖醇。
  29. GC31809 Yangonin

    甲氧醉椒素

     A kavalactone with affinity for the CB1 receptor
  30. GC15632 YM-155 hydrochloride

    YM155 hydrochloride;YM 155 hydrochloride

     A survivin inhibitor
  31. GC13107 YM155

    4,9-二氢-1-(2-甲氧基乙基)-2-甲基-4,9-二氧代-3-(2-吡嗪甲基)-1H-萘并[2,3-D]咪唑溴化物,Sepantronium bromide,YM-155

     A small molecule survivin suppressant
  32. GC10982 YM201636

    6-氨基-N-[3-[4-(4-吗啉基)吡啶并[3',2':4,5]呋喃并[3,2-D]嘧啶-2-基]苯基]-3-吡啶甲酰胺

     Inhibitor of PIKfyve
  33. GN10567 Z-Ligustilide

    藁本内酯

     A phthalide with diverse biological activities
  34. GC12153 Zebularine

    2-嘧啶酮-B-核甙,NSC 309132

     A DNA methyltransferase inhibitor
  35. GC61472 Zingiberene

    α-Zingiberene; (-)-Zingiberene

     Zingiberene(α-Zingiberene)是一种单环倍半萜烯，是姜油的主要成分。具有神经保护潜能。Zingiberene能诱导自噬(autophagy)。具有抗癌活性。
  36. GC13437 ZLN005 A small molecule activator of PGC-1α expression
  37. GC14701 Zoledronic Acid

    唑来膦酸; Zoledronate; CGP 42446; CGP42446A; ZOL 446

     A bisphosphonate that inhibits bone resorption
  38. GC45187 Zoledronic Acid (hydrate)

    唑来膦酸一水合物; Zoledronate monohydrate; CGP 42446 monohydrate; CGP42446A monohydrate; ZOL 446 monohydrate

     A bisphosphonate that inhibits bone resorption
  39. GC13617 ZSTK474

    2-(2-二氟甲基苯并咪唑-1-基)-4,6-二吗啉基-1,3,5-三嗪

     A pan class I PI3K inhibitor
  40. GC64013 ZX-29 ZX-29 is a potent and selective ALK inhibitor with an IC50s of 2.1, 1.3 and 3.9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively.
  41. GC40044 Zymostenol

    Δ8-Cholesterol

     A precursor of cholesterol
  42. GC10734 β-Lapachone

    3,4-二氢-2,2-二甲基-2H-萘并[1,2-B]吡喃-5,6-二酮,ARQ-501; NSC-26326

     β-Lapachone是一种邻萘醌天然产物，具有抗炎、抗菌及抗锥虫等多种生物活性，且能抑制拓扑异构酶I并诱导NAD(P)H:醌氧化还原酶1。

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