EGFR(表皮生长因子受体)

EGFR (epidermal growth factor receptor) is the cell-surface receptor of its specific ligands, including epidermal growth factor and TGFα (transforming growth factor α) and is a receptor tyrosine kinase.

Products for EGFR

Cat.No. 产品名称 Information
GC16244 Icotinib Hydrochloride
盐酸埃克替尼; BPI-2009H
An EGFR inhibitor
GC14295 Gefitinib hydrochloride
盐酸吉非替尼; ZD-1839 hydrochloride
An EGFR inhibitor
GC10627 Erlotinib
埃罗替尼; CP-358774; NSC 718781; OSI-774
Erlotinib是一种有效且口服生物可利用的表皮生长因子受体（EGFR）酪氨酸激酶抑制剂，IC₅₀值为2 nM。
GC14695 CO-1686 (AVL-301)
AVL-301;CNX-419; Rociletinib
A selective inhibitor of mutant EGFR
GC12087 Canertinib dihydrochloride
卡纽替尼二盐酸盐,PD-183805; CI-1033;Canertinib HCl;PD183805; CI103;PD 183805; CI 103
A pan-ErbB tyrosine kinase inhibitor
GC13873 BMS-690514
(3R,4R)-4-氨基-1-[[4-[(3-甲氧基苯基)氨基]吡咯并[2,1-F][1,2,4]三嗪-5-基]甲基]哌啶-3-醇,BMS690514;BMS 690514
BMS-690514 是一种有效的、具有口服活性的 EGFR 和 VEGFR 抑制剂；对 EGFR、HER 2 和 HER 4 的 IC50 分别为 5、20 和 60 nM。
GC10606 BMS-599626 Hydrochloride
AC480;BMS-599626 HCl;BMS599626;BMS 599626;AC-480
BMS-599626 Hydrochloride (AC480 Hydrochloride) 是一种选择性的口服生物可利用的 HER1 和 HER2 抑制剂，IC50 分别为 20 和 30 nM。 BMS-599626 Hydrochloride 对 HER4 (IC50=190 nM) 的效力降低约 8 倍，对 VEGFR2、c-Kit、Lck、MEK 的效力超过 100 倍。 BMS-599626 Hydrochloride 抑制肿瘤细胞增殖，并有可能增加肿瘤对放疗的反应。
GC10087 BIBX 1382
Falnidamol;BIBX-1382;BIBX1382
An EGFR inhibitor
GC10707 Afatinib dimaleate
双马来酸盐阿法替尼; BIBW 2992MA2
An inhibitor of EGFR and ErbB2
GC15589 WHI-P154
2-溴-4-(6,7-二甲氧基喹唑啉-4-基氨基)苯酚
A JAK3 inhibitor
GC16008 CUDC-101
7-[[4-(3-乙炔基苯基氨基)-7-甲氧基喹唑啉-6-基]氧基]-N-羟基庚酰胺,CUDC101, CUDC 101
A multi-target inhibitor of HDACs, EGFR, and HER2
GC12837 Compound 56
N-(3-溴苯基)-6,7-二乙氧基-4-喹唑啉胺
A potent EGFR inhibitor
GN10327 Chrysophanol
大黄酚; Chrysophanic acid
An anthraquinone with diverse biological activities
GN10336 Daphnetin
瑞香素; 7,8-Dihydroxycoumarin
A coumarin derivative with diverse biological activities