Tephrosin is a rotenoid first isolated from the leaves and seeds of T. purpurea and T. vogelii that exhibits antineoplastic and piscicidal activities. The toxic actions of this compound are attributed to its ability to inhibit the NADH:ubiquinone oxidoreductase with an IC50 value of 98nM. Tephrosin is also reported to induce ornithine decarboxylase activity with an IC50 value of 147 nM. Tephrosin has been shown to enhance the cytotoxic activity of 2-deoxy-D-glucose against various cancer human cancer cell lines, depleting intracellular ATP and inducing apoptosis.
Tephrosin (synthetic)
目录号: GC41577纯度: >98.00%同义词: 灰叶草素; Deguelinol I; Hydroxydeguelin
An antineoplastic and piscicidal rotenoid
Cas No.: 76-80-2
| 规格 | 价格 | 库存 | 数量 | 操作 |
|---|---|---|---|---|
| 1mg | ¥5,051.00 | 现货 | 1 |
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Cell187(9):2288-2304 (2024)
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产品描述 Description
产品文档 Product Documents
Purity:>98.00%Appearance:A solid
化学性质Chemical Properties
CAS 号
76-80-2
同义词
灰叶草素; Deguelinol I; Hydroxydeguelin
SMILES
CC(C=C1)(C)OC2=C1C(O3)=C(C=C2)C([C@@]([C@@]3([H])CO4)(O)C5=C4C=C(OC)C(OC)=C5)=O
分子式
C23H22O7
分子量
410.4 g/mol
溶解性
Chloroform: soluble
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。
计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度
g/mol