EGFR
EGFR(表皮生长因子受体)
EGFR (epidermal growth factor receptor) is the cell-surface receptor of its specific ligands, including epidermal growth factor and TGFα (transforming growth factor α) and is a receptor tyrosine kinase.
EGFR 相关产品(264)
- GC12910Canertinib (CI-1033)CAS: 267243-28-7纯度: >99.50%
Canertinib (CI-1033)是一种强效、不可逆的EGFR抑制剂，对EGFR、HER2和HER4的IC 50 值分别为0.8、19和7nM。
- GC13296Afatinib(BIBW2992)CAS: 439081-18-2
Afatinib(BIBW2992)是一种口服、选择性ErbB家族受体酪氨酸激酶（RTK）抑制剂，其对EGFR激酶的IC 50 值为0.05nM，对HER2激酶为14nM，对HER4激酶为1nM。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC12038 | RG 13022 | 136831-48-6 | - | |
An inhibitor of EGF receptor kinase | ||||
| GC12069 | Methyl 2,5-dihydroxycinnamate | 63177-57-1 | - | |
An EGFR tyrosine kinase inhibitor | ||||
| GC12087 | Canertinib dihydrochloride | 289499-45-2 | >99.00% | |
A pan-ErbB tyrosine kinase inhibitor | ||||
| GC12233 | AG 556 | 133550-41-1 | - | |
An EGFR inhibitor | ||||
| GC12281 | EAI045 | 1942114-09-1 | >98.50% | |
A potent inhibitor of mutant EGFRs | ||||
| GC12818 | 4-methyl Erlotinib | 1346601-52-2 | - | |
A methylated analog of erlotinib | ||||
| GC12864 | AG-1557 | 189290-58-2 | >99.50% | |
An EGFR inhibitor | ||||
| GC12910 | Canertinib (CI-1033) | 267243-28-7 | >99.50% | |
Canertinib (CI-1033)是一种强效、不可逆的EGFR抑制剂，对EGFR、HER2和HER4的IC 50 值分别为0.8、19和7nM。 | ||||
| GC12955 | AZ5104 | 1421373-98-9 | >98.00% | |
An active metabolite of AZD 9291 | ||||
| GC12977 | Tyrphostin B44, (-) enantiomer | 133550-32-0 | - | |
EGFR-kinase inhibitor | ||||
| GC13091 | CP-724714 | 383432-38-0 | >99.00% | |
A selective HER2/ErbB2 tyrosine kinase inhibitor | ||||
| GC13143 | AZD3759 | 1626387-80-1 | >99.50% | |
A brain penetrant inhibitor of EGFR | ||||
| GC13168 | AG 825 | 149092-50-2 | >98.00% | |
An inhibitor of Her2/Neu tyrosine kinase activity | ||||
| GC13213 | WZ3146 | 1214265-56-1 | >99.00% | |
An inhibitor of mutant EGFR | ||||
| GC13257 | AC480 (BMS-599626) | 714971-09-2 | - | |
A dual inhibitor of EGFR and HER2 | ||||
| GC13296 | Afatinib(BIBW2992) | 439081-18-2 | - | |
Afatinib(BIBW2992)是一种口服、选择性ErbB家族受体酪氨酸激酶（RTK）抑制剂，其对EGFR激酶的IC 50 值为0.05nM，对HER2激酶为14nM，对HER4激酶为1nM。 | ||||
| GC14102 | Genistein | 446-72-0 | >99.50% | |
染料木黄酮是一种异黄酮，属于类黄酮化合物，存在于多种植物中。 | ||||
| GC14103 | NSC228155 | 113104-25-9 | >98.00% | |
An EGFR activator and inhibitor of KID-KIX interactions | ||||
| GC14136 | BMS 599626 dihydrochloride | 1781932-33-9 | - | |
EGFR and ErbB2 inhibitor,potent and selective | ||||
| GC14259 | HKI 357 | 848133-17-5 | >99.00% | |
An irreversible dual inhibitor of EGFR and HER2 | ||||
| GC14295 | Gefitinib hydrochloride | 184475-55-6 | >99.00% | |
An EGFR inhibitor | ||||
| GC14494 | AG 99 | 122520-85-8 | >99.00% | |
An inhibitor of EGF receptor kinase | ||||
| GC14856 | EGFR/ErbB2 Inhibitor | 179248-61-4 | >99.50% | |
A dual inhibitor of EGFR and ErbB2 | ||||
| GC14890 | AG-183 | 122520-90-5 | >98.00% | |
An inhibitor of EGF receptor kinase | ||||