PKC

PKC(蛋白激酶C)

PKC (protein kinase C) is a serine/threonine protein kinase that mediates insulin signaling, actin cytoskeleton, cell mobility, apoptosis and tumorigenesis etc.

PKC 相关产品(141)

GC17239 Bisindolylmaleimide V
CAS: 113963-68-1
A S6K inhibitor
GC17242 (-)-epigallocatechin
CAS: 970-74-1
纯度: >98.00%
(-)-epigallocatechin是绿茶中的一种主要多酚类化合物，具有抗氧化特性。
GC17346 KT 5823
CAS: 126643-37-6
纯度: >95.00%
Potent selective inhibitor of cGMP-dependent protein kinase (PKG)
GC17352 Phorbol 12,13-dibutyrate
CAS: 37558-16-0
纯度: >99.50%
An activator of PKC
GC17563 LY 333531 hydrochloride
CAS: 169939-93-9
纯度: >98.00%
A PKCβ inhibitor
GC17591 D-erythro-Sphingosine (synthetic)
CAS: 123-78-4
纯度: >98.00%
D-erythro-sphingosine (Erythrosphingosine) 是一种非常有效的 p32 激酶激活剂，EC50 值为 8μM。
GC17670 Bryostatin 1
CAS: 83314-01-6
纯度: >99.00%
A marine macrolide with diverse biological activities
GC17727 [Ala107]-MBP (104-118)
CAS: 99026-77-4
[Ala107]-MBP (104-118) 是一种蛋白激酶 C (PKC) 的非竞争性肽抑制剂，IC50 范围为 46-145 μM。
GC17767 Dihydrosphingosine
CAS: 3102-56-5
A mixture of sphingolipid pathway intermediates
GC17815 L-threo-Sphingosine C-18
CAS: 25695-95-8
A D-erythro-sphingosine analog
GC18055 SC-9
CAS: 102649-78-5
An activator of PKC
GC18062 1,2-Dilauroyl-sn-glycerol
CAS: 60562-15-4
A long-chain DAG
GC18246 R-59-949
CAS: 120166-69-0
纯度: >98.00%
A DGK-α inhibitor
GC18354 Bisindolylmaleimide X (hydrochloride)
CAS: 145317-11-9
纯度: >98.50% / >98.00%
Bisindolylmaleimide X (hydrochloride) 是一种新型的、具有细胞渗透性的蛋白激酶C（PKC）抑制剂。Bisindolylmaleimide X也可抑制细胞周期蛋白依赖性激酶2(CDK2)活性。
GC18521 Cercosporin
CAS: 35082-49-6
纯度: >95.00%
A cytotoxic phytotoxin
GC25662 N-Desmethyltamoxifen
CAS: 31750-48-8
N-Desmethyltamoxifen, the major metabolite of Tamoxifen in humans and a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen, also is a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation.
GC26055 WAY-301398
CAS: 312607-68-4
WAY-301398 (6-methoxynaphthalene) can bind to protein kinase C (PKC).
GC26065 WAY-354831
CAS: 330572-32-2
WAY-354831 exhibits antibacterial activity.
GC30200 PKC-theta inhibitor
CAS: 736048-65-0
纯度: >99.50%
PKC-theta inhibitor (compound 20) inhibits PKC-θ with an IC50 of 18 nM.
GC30545 Malantide
CAS: 86555-35-3
纯度: >98.50%
Malantide是一种十二肽，能够被PKA磷酸化，并且能够增强PKA的活性。
GC31656 Ingenol Mebutate (Ingenol 3-angelate)
CAS: 75567-37-2
纯度: >99.00%
A natural cytotoxic diterpene ester
GC31711 PKC-IN-1
CAS: 1046787-18-1
纯度: >98.00% / >98.50%
PKC-IN-1是一种有效的，ATP-竞争性的，可逆的PKC抑制剂，对人PKCβ和PKCα的Ki值分别为5.3和10.4nM，对人PKCα，PKCβI，PKCβII，PKCθ，PKCγ，PKCmu和PKCε的IC50值分别为2.3，8.1，7.6，25.6，57.5，314，808nM。
GC31892 Decursin ((+)-Decursin)
CAS: 5928-25-6
纯度: >98.00%
A phytochemical with diverse biological activities
GC31912 VTX-27
CAS: 1321924-70-2
纯度: >99.50%
A PKCθ inhibitor

分类产品列表
货号	产品名称	CAS号	纯度
GC17239	Bisindolylmaleimide V	113963-68-1	-
GC17239	A S6K inhibitor
GC17242	(-)-epigallocatechin	970-74-1	>98.00%
GC17242	(-)-epigallocatechin是绿茶中的一种主要多酚类化合物，具有抗氧化特性。
GC17346	KT 5823	126643-37-6	>95.00%
GC17346	Potent selective inhibitor of cGMP-dependent protein kinase (PKG)
GC17352	Phorbol 12,13-dibutyrate	37558-16-0	>99.50%
GC17352	An activator of PKC
GC17563	LY 333531 hydrochloride	169939-93-9	>98.00%
GC17563	A PKCβ inhibitor
GC17591	D-erythro-Sphingosine (synthetic)	123-78-4	>98.00%
GC17591	D-erythro-sphingosine (Erythrosphingosine) 是一种非常有效的 p32 激酶激活剂，EC50 值为 8μM。
GC17670	Bryostatin 1	83314-01-6	>99.00%
GC17670	A marine macrolide with diverse biological activities
GC17727	[Ala107]-MBP (104-118)	99026-77-4	-
GC17727	[Ala107]-MBP (104-118) 是一种蛋白激酶 C (PKC) 的非竞争性肽抑制剂，IC50 范围为 46-145 μM。
GC17767	Dihydrosphingosine	3102-56-5	-
GC17767	A mixture of sphingolipid pathway intermediates
GC17815	L-threo-Sphingosine C-18	25695-95-8	-
GC17815	A D-erythro-sphingosine analog
GC18055	SC-9	102649-78-5	-
GC18055	An activator of PKC
GC18062	1,2-Dilauroyl-sn-glycerol	60562-15-4	-
GC18062	A long-chain DAG
GC18246	R-59-949	120166-69-0	>98.00%
GC18246	A DGK-α inhibitor
GC18354	Bisindolylmaleimide X (hydrochloride)	145317-11-9	>98.50% / >98.00%
GC18354	Bisindolylmaleimide X (hydrochloride) 是一种新型的、具有细胞渗透性的蛋白激酶C（PKC）抑制剂。Bisindolylmaleimide X也可抑制细胞周期蛋白依赖性激酶2(CDK2)活性。
GC18521	Cercosporin	35082-49-6	>95.00%
GC18521	A cytotoxic phytotoxin
GC25662	N-Desmethyltamoxifen	31750-48-8	-
GC25662	N-Desmethyltamoxifen, the major metabolite of Tamoxifen in humans and a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen, also is a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation.
GC26055	WAY-301398	312607-68-4	-
GC26055	WAY-301398 (6-methoxynaphthalene) can bind to protein kinase C (PKC).
GC26065	WAY-354831	330572-32-2	-
GC26065	WAY-354831 exhibits antibacterial activity.
GC30200	PKC-theta inhibitor	736048-65-0	>99.50%
GC30200	PKC-theta inhibitor (compound 20) inhibits PKC-θ with an IC50 of 18 nM.
GC30545	Malantide	86555-35-3	>98.50%
GC30545	Malantide是一种十二肽，能够被PKA磷酸化，并且能够增强PKA的活性。
GC31656	Ingenol Mebutate (Ingenol 3-angelate)	75567-37-2	>99.00%
GC31656	A natural cytotoxic diterpene ester
GC31711	PKC-IN-1	1046787-18-1	>98.00% / >98.50%
GC31711	PKC-IN-1是一种有效的，ATP-竞争性的，可逆的PKC抑制剂，对人PKCβ和PKCα的Ki值分别为5.3和10.4nM，对人PKCα，PKCβI，PKCβII，PKCθ，PKCγ，PKCmu和PKCε的IC50值分别为2.3，8.1，7.6，25.6，57.5，314，808nM。
GC31892	Decursin ((+)-Decursin)	5928-25-6	>98.00%
GC31892	A phytochemical with diverse biological activities
GC31912	VTX-27	1321924-70-2	>99.50%
GC31912	A PKCθ inhibitor