GlpBio

PKC

PKC(蛋白激酶C)

PKC (protein kinase C) is a serine/threonine protein kinase that mediates insulin signaling, actin cytoskeleton, cell mobility, apoptosis and tumorigenesis etc.

PKC 相关产品(141)

  • GC13461 structure
    GC13461ZIP (SCRAMBLED)
    CAS: 908012-18-0

    ZIP (SCRAMBLED) 是 zeta 抑制肽 (ZIP) 的乱序对照肽。

  • GC13677 structure
    GC13677Ro 32-0432 hydrochloride
    CAS: 151342-35-7

    Ro 32-0432 hydrochloride 是一种有效的、选择性的、ATP 竞争性和口服活性的 PKC 抑制剂。

  • GC13869 structure
    GC13869Fasudil
    CAS: 103745-39-7
    纯度: >98.00%

    Fasudil（法舒地尔；HA-1077；AT877）是一种非特异性RhoA/ROCK抑制剂，对ROCK1的K i 为0.33μM，IC 50 为0.158μM，对ROCK2和PKA、PKC、PKG的IC 50 分别为4.58μM、12.30μM、1.650μM。

  • GC13877 structure
    GC138771,2-Dipalmitoyl-sn-glycerol
    CAS: 30334-71-5
    纯度: >95.00% / >97.00%

    A diacylglycerol

  • GC13890 structure
    GC13890(±)-Palmitoylcarnitine chloride
    CAS: 6865-14-1

    A long-chain acylcarnitine with intracellular and extracellular roles

  • GC14012 structure
    GC14012(-)-Indolactam V
    CAS: 90365-57-4
    纯度: >98.00%

    A PKC activator

  • GC14134 structure
    GC141341,2-Dimyristoyl-sn-glycerol
    CAS: 60562-16-5

    A long-chain DAG

  • GC14289 structure
    GC14289Fasudil (HA-1077) HCl
    CAS: 105628-07-7
    纯度: >99.50% / >98.00%

    Fasudil (HA-1077) HCl（法舒地尔；HA-1077；AT877）是一种非特异性RhoA/ROCK抑制剂，对ROCK1的K i 为0.33μM，IC 50 为0.158μM，对ROCK2和PKA、PKC、PKG的IC 50 分别为4.58μM、12.30μM、1.650μM。

  • GC14363 structure
    GC14363Mitoxantrone HCl
    CAS: 70476-82-3
    纯度: >98.00%

    An inhibitor of DNA topoisomerase IIα and HIV-1 integrase

  • GC14583 structure
    GC14583R 59-022
    CAS: 93076-89-2
    纯度: 不显示

    R 59-022是一种二酰甘油激酶抑制剂（IC 50 = 2.8µM）。

  • GC14650 structure
    GC14650CGP60474
    CAS: 164658-13-3
    纯度: >98.50%

    A CDK inhibitor

  • GC14716 structure
    GC14716Bisindolylmaleimide IV
    CAS: 119139-23-0
    纯度: >98.50% / >97.00%

    Bisindolylmaleimide IV 是一种强效的细胞膜透过性蛋白激酶C(PKC)抑制剂，其IC 50 值为0.1-0.55μM。

  • GC15018 structure
    GC15018Hispidin
    CAS: 555-55-5
    纯度: >99.50%

    A polyphenol with diverse biological activities

  • GC15148 structure
    GC15148Ionomycin calcium salt
    CAS: 56092-82-1
    纯度: >98.00%

    Ionomycin calcium salt是一种窄谱抗生素,对革兰氏阳性菌具有活性,由丛生链霉菌(Streptomyces conglobatus)产生。

  • GC15345 structure
    GC15345[Ala113]-MBP (104-118)
    CAS: 99026-78-5

    [Ala113]-MBP (104-118) 是一种蛋白激酶 C (PKC) 的非竞争性肽抑制剂，IC50 范围为 28-62 μM。

  • GC15446 structure
    GC15446Ionomycin free acid
    CAS: 56092-81-0
    纯度: {{1-15}>98.00%}

    Ionomycin free acid 是一种选择性的强效钙离子载体，可作为活性 Ca2+ 载体。

  • GC15471 structure
    GC15471PKC β pseudosubstrate
    CAS: 172308-76-8

    Selective cell-permeable peptide inhibitor of protein kinase C

  • GC15564 structure
    GC15564Go 6976
    CAS: 136194-77-9
    纯度: >99.00% / >98.00%

    Go 6976 是一种有效的蛋白激酶(PKs)抑制剂，对PKC、cGMP依赖性蛋白激酶和肌球蛋白轻链激酶的IC 50 值分别为0.02μM、6.2μM和5.8μM。

  • GC16405 structure
    GC16405Safingol
    CAS: 15639-50-6

    A dual inhibitor of PKC and SPHK

  • GC16475 structure
    GC16475Afuresertib
    CAS: 1047644-62-1
    纯度: >99.50%

    A pan-Akt inhibitor

  • GC16510 structure
    GC16510ZIP, Biotinylated

    ZIP with a biotin moiety covalently attached

  • GC16584 structure
    GC16584TCS 21311
    CAS: 1260181-14-3
    纯度: >95.00%

    A JAK3 inhibitor

  • GC16678 structure
    GC16678UCN-02
    CAS: 121569-61-7

    A PKC inhibitor

  • GC16934 structure
    GC16934Valrubicin
    CAS: 56124-62-0
    纯度: >99.50%

    A semisynthetic anthracycline antitumor antibiotic