GlpBio

N-Desmethyltamoxifen

目录号: GC25662纯度: >98%
COASDSData Sheet
N-Desmethyltamoxifen, the major metabolite of Tamoxifen in humans and a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen, also is a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation.
N-Desmethyltamoxifen
Cas No.: 31750-48-8
规格价格库存数量操作
5mg¥1,090.00现货
1
25mg¥3,268.00现货
1
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文献被引

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    31, 1291–1307 (2021)

产品描述 Description

N-Desmethyltamoxifen, the major metabolite of Tamoxifen in humans and a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen, also is a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation.

[1] Vertosick FT Jr, et al. J Neurooncol. 1994;19(2):97-103. [2] Morad SA, et al. Biochim Biophys Acta. 2015 Jul;1851(7):919-28.

产品文档 Product Documents

Purity:>98%
COASDSData Sheet

化学性质Chemical Properties

CAS 号
31750-48-8
分子式
C25H27NO
分子量
357.49 g/mol
溶解性
DMSO: 72 mg/mL (201.40 mM);Water: Insoluble;Ethanol: 36 mg/mL (100.70 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol