Malantide is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.
Malantide is a dodecapeptide, and increases PKA activity in a variety of tissues[1]. Malantide is phosphorylated by PKA[2].
[1]. Murray KJ, et al. Use of a synthetic dodecapeptide (malantide) to measure the cyclic AMP-dependent protein kinase activity ratio in a variety of tissues. Biochem J. 1990 May 1;267(3):703-8. [2]. de Boer AR, et al. Systematic development of an enzymatic phosphorylation assay compatible with mass spectrometric detection. Anal Bioanal Chem. 2005 Feb;381(3):647-55.