GlpBio

Endogenous Metabolite

Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Endogenous Metabolite 相关产品(1712)

  • GC13161 structure
    GC13161Escitalopram
    CAS: 128196-01-0

    Escitalopram是一种高选择性的5-羟色胺再摄取抑制剂（K i =0.89nM）。

  • GC13172 structure
    GC13172Adenosine 5-monophosphate
    CAS: 61-19-8
    纯度: >99.00%

    5-单磷酸腺苷是调节能量稳态和信号转导的关键细胞代谢物。

  • GC13206 structure
    GC13206Nicotinic Acid
    CAS: 59-67-6
    纯度: >99.50%

    烟酸（维生素 B3）是一种具有口服活性的水溶性维生素 B3，是人体必需的营养素。

  • GC13216 structure
    GC13216trans-trans Muconic acid
    CAS: 3588-17-8
    纯度: >98.00%

    trans-trans Muconic acid 是一种苯的尿代谢物，已被用作人体接触苯的生物标志物。

  • GC13228 structure
    GC13228Phosphocreatine disodium salt
    CAS: 922-32-7
    纯度: >98.00% / >97.00%

    Phosphocreatine disodium salt是肌肉和大脑等高能量波动需求组织中的重要能量储备物质。

  • GC13363 structure
    GC13363Ursodiol
    CAS: 128-13-2
    纯度: >98.00%

    Ursodiol（UDCA）是一种微生物通过初级胆汁酸鹅去氧胆酸（CDCA）的7α/β 异构化转化而来的次级胆汁酸。Ursodiol可用于多种肝脏疾病和胃肠道疾病的研究。

  • GC13377 structure
    GC133773-hydroxy Anthranilic Acid
    CAS: 548-93-6
    纯度: >95.00%

    A tryptophan metabolite

  • GC13392 structure
    GC13392Flavin adenine dinucleotide
    CAS: 146-14-5
    纯度: >98.00% / >97.00%

    Flavin adenine dinucleotide（黄素腺嘌呤二核苷酸，FAD）是一种重要的氧化还原辅因子，广泛参与细胞的能量代谢和电子传递过程。

  • GC13432 structure
    GC13432Adenine
    CAS: 73-24-5
    纯度: >99.50% / >98.50%

    腺嘌呤（6-氨基嘌呤）是一种嘌呤，是DNA核酸中的四种核碱基之一。腺嘌呤是DNA和RNA的化学成分。腺嘌呤还在涉及细胞呼吸、ATP 和辅因子（NAD 和 FAD）的形式以及蛋白质合成的生物化学中发挥重要作用。

  • GC13441 structure
    GC13441Cyclopamine
    CAS: 4449-51-8
    纯度: >99.50%

    Cyclopamine是一种天然存在的Hedgehog (Hh)特异性小分子信号甾体生物碱抑制剂，对肿瘤生长具有深远的抑制作用，在人乳腺癌细胞中具有显著的抗侵袭、抗增殖和抗雌激素活性。

  • GC13502 structure
    GC13502Cysteamine HCl
    CAS: 156-57-0
    纯度: >98.00%

    A radioprotective aminothiol

  • GC13531 structure
    GC13531Deoxyadenosine 5-triphosphate
    CAS: 1927-31-7
    纯度: >98.00%

    Deoxyadenosine 5-triphosphate是一种由一个腺嘌呤碱基、一个脱氧核糖和三个磷酸基团组成的脱氧核苷酸三磷酸。

  • GC13571 structure
    GC135712-Deoxyuridine
    CAS: 951-78-0
    纯度: >98.00%

    A pyrimidine nucleoside

  • GC13670 structure
    GC13670Methylmalonate
    CAS: 516-05-2
    纯度: >98.00%

    A dicarboxylic acid and byproduct of propionate catabolism

  • GC13729 structure
    GC13729Cytidine
    CAS: 65-46-3
    纯度: >99.50% / >98.00%

    A pyrimidine nucleoside

  • GC13742 structure
    GC13742Uridine
    CAS: 58-96-8
    纯度: >99.50%

    Uridine是一种核苷，包含尿嘧啶，通过β-N1-糖苷键与核糖环连接。

  • GC13749 structure
    GC13749O-Phosphorylethanolamine
    CAS: 1071-23-4
    纯度: >98.00%

    A phospholipid metabolite

  • GC13804 structure
    GC13804Ercalcidiol
    CAS: 21343-40-8
    纯度: >99.00%

    Ercalcidiol是一种可反映体内维生素D营养水平的维生素D 2 代谢物。

  • GC13852 structure
    GC13852Calcitriol
    CAS: 32222-06-3
    纯度: >99.00% / >99.50%

    骨化三醇作为类固醇激素维生素 D 的最具生物活性的代谢产物，抑制骨化三醇会导致抗癌药物的作用降低。

  • GC13877 structure
    GC138771,2-Dipalmitoyl-sn-glycerol
    CAS: 30334-71-5
    纯度: >95.00% / >97.00%

    A diacylglycerol

  • GC13887 structure
    GC1388725(R)-27-hydroxy Cholesterol
    CAS: 20380-11-4
    纯度: >98.00%

    25(R)-27-hydroxy Cholesterol是肝脏X受体（LXR）α和LXRβ的激动剂，EC 50 值分别为0.085μM和0.071μM。

  • GC13890 structure
    GC13890(±)-Palmitoylcarnitine chloride
    CAS: 6865-14-1

    A long-chain acylcarnitine with intracellular and extracellular roles

  • GC13955 structure
    GC13955Enoxolone
    CAS: 471-53-4
    纯度: >99.50% / >98.00%

    An anti-inflammatory and immunomodulatory compound

  • GC14042 structure
    GC14042Oleamide
    CAS: 301-02-0
    纯度: >65.00%

    An amide of oleic acid and agonist of CB 1 receptors