GlpBio

Endogenous Metabolite

Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Endogenous Metabolite 相关产品(1712)

  • GC11969 structure
    GC11969Adenosine-5'-diphosphate
    CAS: 58-64-0
    纯度: >98.00% / >99.50%

    Adenosine-5'-diphosphate是 P2Y1、P2Y12、P2Y13 等嘌呤能 P2Y 受体的天然激动剂，可直接结合并触发下游信号级联。

  • GC12040 structure
    GC12040L-Kynurenine
    CAS: 2922-83-0
    纯度: >98.00%

    L-Kynurenine是L-色氨酸的代谢物，也是一种芳香烃受体 (aryl hydrocarbon receptor; AhR) 激动剂。

  • GC12123 structure
    GC12123sn-Glycero-3-phosphocholine
    CAS: 28319-77-9
    纯度: >98.00%

    A nootropic phospholipid

  • GC12148 structure
    GC12148Ethinyl Estradiol
    CAS: 57-63-6
    纯度: >99.50%

    A 17β-estradiol analog

  • GC12182 structure
    GC12182Estriol
    CAS: 50-27-1
    纯度: >99.00%

    Estriol是雌激素受体（ERα和ERβ）的激动剂和G蛋白偶联受体30（GPR30）的拮抗剂。

  • GC12203 structure
    GC12203L-Glutathione Reduced
    CAS: 70-18-8
    纯度: >99.00% / >97.00%

    Nucleophilic co-substrate to glutathione transferases and electron donor to glutathione peroxidases

  • GC12256 structure
    GC12256D-Mannitol
    CAS: 69-65-8
    纯度: >99.00%

    An Analytical Reference Standard

  • GC12327 structure
    GC12327Corticosterone
    CAS: 50-22-6
    纯度: >99.50% / >97.00% / >98.00% / >99.00%

    Corticosterone (17 deoxycortisol) 是一种具有口服活性的糖皮质激素，由肾上腺皮质产生，对调节边缘系统（包括海马、前额叶皮层和杏仁核）的神经元功能具有重要作用。

  • GC12349 structure
    GC12349Deoxycorticosterone acetate
    CAS: 56-47-3
    纯度: >98.00%

    A corticosteroid

  • GC12395 structure
    GC12395(D)-(+)-Neopterin
    CAS: 2009-64-5
    纯度: >98.00%

    A biochemical tool to screen for immune disorders

  • GC12408 structure
    GC12408Progesterone
    CAS: 57-83-0
    纯度: >98.00%

    An endogenous hormone and hormone precursor

  • GC12518 structure
    GC12518L-Dihydroorotic acid
    CAS: 5988-19-2
    纯度: >98.00%

    L-二氢乳清酸可以通过二氢乳清酶可逆地水解产生无环L-脲基琥珀酸。

  • GC12664 structure
    GC12664Urea
    CAS: 57-13-6
    纯度: >98.00% / >99.00%

    尿素是一种强大的蛋白质变性剂，通过直接和间接机制。

  • GC12713 structure
    GC127135-Aminovaleric acid hydrochloride
    CAS: 660-88-8
    纯度: >98.00%

    5-氨基戊酸盐酸盐被认为是 γ-氨基丁酸 (GABA) 的亚甲基同系物，并作为弱 GABA 激动剂发挥作用。

  • GC12715 structure
    GC12715Synephrine HCl
    CAS: 5985-28-4
    纯度: >99.50%

    An alkaloid

  • GC12809 structure
    GC12809Itaconic acid
    CAS: 97-65-4
    纯度: >98.00%

    Itaconic acid是一种不饱和二羧酸，可由原核生物和真菌合成，也可在哺乳动物巨噬细胞感染过程中由乌头酸脱羧酶1（ACOD1，也称为IRG1）产生和分泌。

  • GC12829 structure
    GC128295-hydroxy Tryptophol
    CAS: 154-02-9
    纯度: >98.00%

    A metabolite of tryptophan

  • GC12850 structure
    GC128502-Deoxy-D-ribose
    CAS: 533-67-5

    A reducing sugar

  • GC12917 structure
    GC12917Acetaminophen
    CAS: 103-90-2
    纯度: >99.00%

    An analgesic and antipyretic compound

  • GC12920 structure
    GC12920Pregnenolone
    CAS: 145-13-1
    纯度: >98.00%

    A natural steroid hormone

  • GC12964 structure
    GC129642-3-Dihydroxybenzoic acid
    CAS: 303-38-8

    2-3-二羟基苯甲酸是一种在血浆中发现的正常人体苯甲酸代谢物，在服用阿司匹林后水平会升高。

  • GC12974 structure
    GC12974Medroxyprogesterone acetate
    CAS: 71-58-9
    纯度: >99.50%

    Medroxyprogesterone acetate（MPA）是一种人工合成的孕激素。

  • GC13072 structure
    GC13072Epiandrosterone
    CAS: 481-29-8
    纯度: >98.00%

    An Analytical Reference Standard

  • GC13084 structure
    GC13084Ketoisovaleric acid
    CAS: 759-05-7
    纯度: >98.00%

    Ketoisovaleric acid（KIV）是亮氨酸和缬氨酸合成的前体。