GlpBio

Endogenous Metabolite

Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Endogenous Metabolite 相关产品(1712)

  • GC11029 structure
    GC11029Isoprenaline HCl
    CAS: 51-30-9
    纯度: >99.00%

    A β 1 - and β 2 -AR agonist

  • GC11064 structure
    GC11064Spermine tetrahydrochloride
    CAS: 306-67-2
    纯度: >99.00%

    A natural polyamine

  • GC11070 structure
    GC11070Dehydroepiandrosterone (DHEA)
    CAS: 53-43-0
    纯度: >99.00%

    脱氢表雄酮 (DHEA) 及其硫酸酯 DHEAS 共同代表了人体内最丰富的类固醇激素。

  • GC11139 structure
    GC111391-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC
    CAS: 35418-59-8
    纯度: >98.00%

    A phospholipid

  • GC11195 structure
    GC11195Sarcosine
    CAS: 107-97-1
    纯度: >98.00%

    An intermediate in the biosynthesis of glycine

  • GC11222 structure
    GC11222Methylthioadenosine
    CAS: 2457-80-9
    纯度: >99.50% / >97.00%

    Methylthioadenosine是多胺生物合成过程中由 S-腺苷甲硫氨酸(SAMe)产生的含硫腺嘌呤核苷。Methylthioadenosine常用于结肠炎、肝病和各种癌症疾病的研究。

  • GC11236 structure
    GC11236[Leu5]-Enkephalin
    CAS: 58822-25-6
    纯度: >99.50%

    [Leu5]-Enkephalin是一种通过与阿片受体结合以调节疼痛感知和情绪的内源性δ阿片受体激动剂。

  • GC11242 structure
    GC11242Calcium Gluceptate
    CAS: 17140-60-2

    葡萄糖酸钙是一种内源性代谢物。

  • GC11268 structure
    GC11268L-Thyroxine
    CAS: 51-48-9
    纯度: >98.00%

    L-Thyroxine是一种合成甲状腺激素，可模拟甲状腺分泌的天然甲状腺素，对调节新陈代谢、促进生长发育等起着关键作用。L-Thyroxine常用于治疗甲状腺功能减退症及其他甲状腺相关疾病。

  • GC11270 structure
    GC112704-Hydroxybenzoic acid
    CAS: 99-96-7
    纯度: >98.00%

    A phenolic acid

  • GC11272 structure
    GC11272Phenylephrine HCl
    CAS: 61-76-7
    纯度: >99.50%

    Phenylephrine HCl（盐酸去氧肾上腺素）是一种选择性的α1-肾上腺素能受体激动剂。

  • GC11282 structure
    GC11282β-Estradiol
    CAS: 50-28-2
    纯度: >99.50%

    The major premenopausal estrogen

  • GC11344 structure
    GC11344Eicosapentaenoic Acid
    CAS: 10417-94-4
    纯度: >98.00% / >97.00%

    Eicosapentaenoic Acid（EPA）二十碳五烯酸是一种具有口服活性的omega-3（ω-3）长链多不饱和脂肪酸（PUFA），是前列腺素3、血栓素3和白三烯5类二十烷酸的前体。

  • GC11357 structure
    GC11357Dihomo-γ-Linolenic Acid
    CAS: 1783-84-2
    纯度: >98.00% / >98.00%% / >99.00%

    ω-6 fatty acid intermediate

  • GC11459 structure
    GC11459Xanthurenic acid
    CAS: 59-00-7
    纯度: >99.50% / >98.00%

    Xanthurenic acid是一种内源性II组代谢型谷氨酸受体激动剂，参与丘脑的感觉传递。

  • GC11528 structure
    GC11528Orotic acid
    CAS: 65-86-1
    纯度: >98.00%

    乳清酸 (6-Carboxyuracil) 是嘧啶核苷酸和 RNA 生物合成的前体，从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放出来，通过细胞质 UMP 合酶转化为 UMP。

  • GC11551 structure
    GC11551Hydrocortisone
    CAS: 50-23-7
    纯度: >99.50% / >98.00%

    氢化可的松是一种由肾上腺和肾上腺外组织分泌的天然糖皮质激素，通过与其同源糖皮质激素受体 (GR) 结合，局部控制参与炎症、免疫反应、新陈代谢和能量稳态的基因的转录 。

  • GC11581 structure
    GC115812-Deoxyinosine
    CAS: 890-38-0
    纯度: >98.00%

    A nucleoside form of hypoxanthine

  • GC11642 structure
    GC116422-Deoxyadenosine
    CAS: 958-09-8
    纯度: >98.00%

    2-Deoxyadenosine 是一种核苷腺苷衍生物，与双链 DNA 中的脱氧胸苷 (T) 配对。

  • GC11786 structure
    GC11786Acetylcysteine
    CAS: 616-91-1
    纯度: >99.00%

    乙酰半胱氨酸是半胱氨酸的 N-乙酰基衍生物。

  • GC11828 structure
    GC11828N-carbamoyl-DL-aspartic acid
    CAS: 923-37-5

    An intermediate in pyrimidine biosynthesis

  • GC11843 structure
    GC11843Azaguanine-8
    CAS: 134-58-7
    纯度: >98.00%

    Azaguanine-8 是一种嘌呤类似物，具有抗肿瘤活性。 Azaguanine-8 起抗代谢物的作用，很容易与核糖核酸结合，干扰正常的生物合成途径，从而抑制细胞生长。

  • GC11872 structure
    GC11872Creatinine
    CAS: 60-27-5
    纯度: >99.50%

    The end product of the creatine-creatine phosphate energy shuttle

  • GC11941 structure
    GC11941Flavin adenine dinucleotide disodium
    CAS: 84366-81-4
    纯度: >98.00% / >95.00% / >99.00%

    Flavin adenine dinucleotide disodium（黄素腺嘌呤二核苷酸，FAD）是一种重要的氧化还原辅因子，广泛参与细胞的能量代谢和电子传递过程。