GlpBio

Endogenous Metabolite

Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Endogenous Metabolite 相关产品(1712)

  • GC14055 structure
    GC14055Vanillin
    CAS: 121-33-5
    纯度: >99.50%

    An Analytical Reference Standard

  • GC14098 structure
    GC14098Menadione
    CAS: 58-27-5
    纯度: >98.00%

    A provitamin

  • GC14106 structure
    GC14106Adenosine
    CAS: 58-61-7
    纯度: >99.50% / >99.00%

    Adenosine是一种内源性神经调节物质，包含腺嘌呤，通过β-N9-糖苷键与核糖分子（呋喃核糖）部分连接。

  • GC14142 structure
    GC14142Acetylcholine Chloride
    CAS: 60-31-1
    纯度: >99.00% / >98.00%

    A neurotransmitter

  • GC14203 structure
    GC14203Citric acid
    CAS: 77-92-9
    纯度: >99.00% / >98.00%

    柠檬酸是一种天然防腐剂和食品酸味增强剂。

  • GC14301 structure
    GC14301Spaglumic acid
    CAS: 3106-85-2
    纯度: >98.00%

    A peptide neurotransmitter

  • GC14331 structure
    GC14331Folinic acid
    CAS: 58-05-9
    纯度: >99.50%

    亚叶酸 (Leucovorin) 是一种生物叶酸，通常与甲氨蝶呤 (MTX) 一起作为救援剂给药，以降低 MTX 诱导的毒性。

  • GC14385 structure
    GC14385Estrone
    CAS: 53-16-7
    纯度: >98.00%

    Estrone是三种主要的内源性雌激素之一，其他是雌二醇和雌三醇。

  • GC14433 structure
    GC144337α,25-dihydroxy Cholesterol
    CAS: 64907-22-8
    纯度: ≥95.00% / >99.50%

    A potent and selective agonist of GPR183

  • GC14511 structure
    GC14511All-trans Retinal
    CAS: 116-31-4
    纯度: >98.00%

    All-trans Retinal 是一种具有活性的vitamin A aldehyde，对CRBP-I和CRBP-II蛋白的K d 值分别为50nM和90nM。

  • GC14533 structure
    GC14533Kynurenic acid
    CAS: 492-27-3
    纯度: >99.00% / >98.00%

    Kynurenic acid 是一种内源性色氨酸代谢物，是一种针对 NMDA、谷氨酸、α7 烟碱乙酰胆碱受体的广谱拮抗剂。

  • GC14547 structure
    GC14547Quinolinic acid
    CAS: 89-00-9
    纯度: >99.00%

    An excitotoxic agonist at NMDA receptors

  • GC14549 structure
    GC145493-Hydroxyphenylacetic acid
    CAS: 621-37-4

    A phenolic acid with diverse biological activities

  • GC14573 structure
    GC14573Xylose
    CAS: 25990-60-7
    纯度: >98.00%

    木糖是有机合成的中间体。

  • GC14816 structure
    GC14816L-Adrenaline
    CAS: 51-43-4
    纯度: >99.50% / >98.00%

    An adrenergic receptor agonist

  • GC14843 structure
    GC14843Serotonin HCl
    CAS: 153-98-0
    纯度: >99.50% / >98.00%

    Serotonin HCl是一种神经递质，是介导人体多种中枢和外周功能的关键信使。

  • GC14943 structure
    GC14943Hypotaurine
    CAS: 300-84-5
    纯度: >99.50% / >98.00%

    Hypotaurine是牛磺酸生物合成的前体，是甘氨酸受体（glycine receptor）的内源性抑制性氨基酸。

  • GC14953 structure
    GC14953Spermine
    CAS: 71-44-3
    纯度: >99.00% / >97.00%

    A natural polyamine

  • GC14954 structure
    GC14954L-Canaline
    CAS: 496-93-5
    纯度: >95.00%

    A natural inhibitor of aminotransferases

  • GC15084 structure
    GC150842-Methoxyestradiol (2-MeOE2)
    CAS: 362-07-2
    纯度: >99.50% / >98.00%

    2-Methoxyestradiol (2-MeOE2/2-Me)是一种HIF-1α抑制剂。

  • GC15095 structure
    GC15095Levodopa
    CAS: 59-92-7
    纯度: >99.00%

    A dopamine precursor

  • GC15129 structure
    GC15129N-Acetylneuraminic acid
    CAS: 131-48-6
    纯度: >98.00%

    N-Acetylneuraminic acid是一种天然存在于结肠中的唾液酸。N-Acetylneuraminic acid作为细胞表面糖蛋白和糖脂的关键组成成分，参与细胞识别、信号传导与黏附。

  • GC15161 structure
    GC15161Calcium D-Panthotenate
    CAS: 137-08-6
    纯度: >98.00% / >99.00%

    D-泛酸钙（维生素B5钙盐）是一种维生素，可以降低苹果汁中棒曲霉素的含量。

  • GC15184 structure
    GC15184Taurine
    CAS: 107-35-7
    纯度: >99.00%

    A sulfur-containing amino acid