PI3K

An inhibitor of platelet aggregation

An inhibitor of platelet aggregation

Hederacolchiside A1 是从白头翁中分离的，通过调节 PI3K/Akt/mTOR 信号通路诱导凋亡，从而抑制肿瘤细胞的增殖。Hederacolchiside A1 具有抗血吸虫病活性，影响体内和体外的寄生虫生存力。

Heterophyllin B is an active cyclic peptide isolated from Pseudostellaria heterophylla, which provides a novel strategy for the treatment of esophageal cancer.

A coumarin with diverse actions

A triterpene with diverse biological activities

rac-AZD 6482 (rac-KIN-193) 是 AZD 6482 的低活性外消旋体，AZD 6482 是一种有效的选择性 p110β 抑制剂，IC50 为 0.69 nM。

An mTOR inhibitor

An active metabolite of daidzein

Glaucocalyxin A is a biologically active ent-kauranoid diterpenoid isolated from Rabdosia japonica var. glaucocalyx with antitumor and anti-inflammatory activity. Glaucocalyxin A induces G2/M cell cycle arrest and apoptosis through the PI3K/Akt pathway in human bladder cancer cells.

A 22- carbon monounsaturated fatty acid

An iminosugar with diverse biological activities

A potent inhibitor of PI3Kγ

Dual inhibitor of PI3K and mTOR

Prototypical PI 3-kinase inhibitor; also inhibits other kinases

强效选择性 PI 3-激酶 δ；抑制剂；口服生物利用度

SKI V is a noncompetitive and potent inhibitor of non-lipid sphingosine kinase with IC50 of 2 μM for GST-hSK. SKI-V also inhibits PI3K with IC50 of 6 μM for hPI3k. SKI-V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P) and induces apoptosis with antitumor activity.

Disitertide TFA是转化生长因子β1（TGF-β1）受体I型的特异性抑制剂。

Quercetin D5是天然产物槲皮素（Quercetin）的氘代同位素内标，其化学结构通常在槲皮素的A环上由5个D原子取代了原有的5个H原子。

hSMG-1 inhibitor 11j是一种嘧啶衍生物，是一种强效且选择性的hSMG-1抑制剂，IC 50 值为0.11nM。

A dual PI3K and mTOR inhibitor

NVS-PI3-4 是一种特异性 PI3Kγ 抑制剂。 NVS-PI3-4 可用于过敏，炎症和癌症疾病的研究。

An inhibitor of PI3Kα, PI3Kβ, and PI3Kδ

AZ2 是一种高度选择性的 PI3Kγ 抑制剂（PI3Kγ 的 pIC50 为 9.3）。AZ2 可用于炎症和免疫疾病的研究。