GlpBio

SKI V

目录号: GC60339纯度: >98.00%同义词: 2-(3,4-二羟基亚苄基)苯并呋喃-3(2H)-酮
SKI V is a noncompetitive and potent inhibitor of non-lipid sphingosine kinase with IC50 of 2 μM for GST-hSK. SKI-V also inhibits PI3K with IC50 of 6 μM for hPI3k. SKI-V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P) and induces apoptosis with antitumor activity.
SKI V
Cas No.: 24418-86-8
规格价格库存数量操作
1mg¥559.00现货
1
5mg¥1,350.00现货
1
10mg¥2,228.00现货
1
25mg¥4,140.00现货
1
10mM (in 1mL DMSO)¥1,563.00现货
1
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产品描述 Description

SKI V is a noncompetitive and potent inhibitor of non-lipid sphingosine kinase with IC50 of 2 μM for GST-hSK. SKI-V also inhibits PI3K with IC50 of 6 μM for hPI3k. SKI-V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P) and induces apoptosis with antitumor activity.

[1] Kevin J French, et al. J Pharmacol Exp Ther. 2006 Aug;318(2):596-603. [2] Kevin J French, et al. Cancer Res. 2003 Sep 15;63(18):5962-9.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
24418-86-8
同义词
2-(3,4-二羟基亚苄基)苯并呋喃-3(2H)-酮
SMILES
O=C1/C(OC2=CC=CC=C12)=C/C3=CC=C(O)C(O)=C3
分子式
C15H10O4
分子量
254.24 g/mol
溶解性
DMSO: 250 mg/mL (983.32 mM)
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol