P450
Cytochrome P450 are a family of heme-containing monoxygenases catalyzing the metabolism of xenobiotics in the body where P450 enzymes use O2 and two electrons provided by NAD(P)H with the help of redox partner flavoproteins and iron-sulfur proteins to catalyze the monooxygenation of a variety of substrates. Based on how electrons from NAD(P)H are delivered to the catalytic site, P450 enzymes are divided into four classes, including Class I requiring both an FAD-containing reductase and an iron sulfur redoxin, Class II requiring only an FAD/FMN-containg P450 reductase, Class III requiring no electron donor and Class IV requiring electrons directly from NAD(P)H.
P450 相关产品(439)
- GC91375Promethazine SulfoxideCAS: 7640-51-9纯度: >95.00%
盐酸普罗米嗪是组胺H1受体拮抗剂普罗米嗪的代谢产物。它由细胞色素P450（CYP）同工酶CYP2D6将普罗米嗪转化而成。
- GC91418(E)-KPT-330CAS: 1421923-86-5纯度: >95.00%
(E)-KPT-330是selinexor的代谢产物，它是exportin 1 (XPO1/CRM1)抑制剂的一种。它由细胞色素P450（CYP）亚型CYP3A4从selinexor中形成。
- GC91705Etomidate-d5纯度: >99.00%
Etomidate-d5 is intended for use as an internal standard for the quantification of etomidate by GC- or LC-MS.
- GN10200Salvianolic acid CCAS: 115841-09-3纯度: >98.00%
Salvianolic acid C 是一种非竞争性细胞色素 P4502C8 (CYP2C8) 抑制剂和细胞色素 P45022J2 (CYP2J2) 的中度混合抑制剂，对 CYP2C8 和 CYP2J2 的 Kis 分别为 4.82 μM 和 5.75 μM。
- GN102415-MethoxypsoralenCAS: 484-20-8纯度: >99.50%
A furanocoumarin derivative with diverse biological activities
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC74692 | (R)-(+)-Aminoglutethimide | 55511-44-9 | >97.00% | |
(R)-(+)-Aminoglutethimide是一种强效的口服芳香化酶抑制剂。 | ||||
| GC90195 | Posaconazole-d5 | 2649530-57-2 | >98.00% | |
一种用于量化泊沙康唑的内部标准。 | ||||
| GC90350 | 14S(15R)-EET methyl ester | 110901-52-5 | >95.00% | |
一种花生四烯酸的细胞色素P450代谢产物。 | ||||
| GC90937 | 1,2,3,4,7,8,9-Heptachlorodibenzofuran | 55673-89-7 | >95.00% | |
一种类似二恶英的多氯联苯。 | ||||
| GC90938 | 1,2,3,4,7,8-Hexachlorodibenzofuran | 70648-26-9 | >90.00% | |
一种类似二恶英的多氯联苯。 | ||||
| GC90942 | 1,2,3,4,6,7,8,9-Octachlorodibenzofuran | 39001-02-0 | >95.00% | |
一种类似二恶英的多氯联苯。 | ||||
| GC91041 | Soluble Epoxide Hydrolase PROTAC 1a | - | >95.00% | |
一种促进sEH降解的PROTAC | ||||
| GC91062 | (±)7(S),8(R)-EDT | 355016-21-6 | >95.00% | |
一个氧脂素 | ||||
| GC91064 | (±)10,11-EDT | 355016-20-5 | >98.00% | |
一种肾上腺酸的代谢产物。 | ||||
| GC91065 | (±)13,14-EDT | 355016-19-2 | >98.00% | |
一种肾上腺酸的代谢产物。 | ||||
| GC91066 | (±)13,14-DiHDoTrE | 944908-94-5 | >95.00% | |
一个氧脂素 | ||||
| GC91067 | (±)16,17-EDT | 351533-79-4 | >98.00% | |
一种肾上腺酸的代谢产物。 | ||||
| GC91128 | Imazalil-d5 (sulfate) | 1398065-92-3 | >99.00% | |
一种用于量化伊马唑啉的内部标准 | ||||
| GC91189 | Piperonyl Butoxide-d9 | 1329834-53-8 | >99.00% | |
一种用于定量苯甲酸对氧乙基的内部标准。 | ||||
| GC91226 | 10-Chloroestra-1,4-diene-3,17-dione | 91413-55-7 | >95.00% | |
一种雌激素受体α激动剂 | ||||
| GC91296 | p-Carboxyphenyl Sulfate | 3233-38-3 | >95.00% | |
一种硫酸化的酚酸。 | ||||
| GC91375 | Promethazine Sulfoxide | 7640-51-9 | >95.00% | |
盐酸普罗米嗪是组胺H1受体拮抗剂普罗米嗪的代谢产物。它由细胞色素P450（CYP）同工酶CYP2D6将普罗米嗪转化而成。 | ||||
| GC91418 | (E)-KPT-330 | 1421923-86-5 | >95.00% | |
(E)-KPT-330是selinexor的代谢产物，它是exportin 1 (XPO1/CRM1)抑制剂的一种。它由细胞色素P450（CYP）亚型CYP3A4从selinexor中形成。 | ||||
| GC91705 | Etomidate-d5 | - | >99.00% | |
Etomidate-d5 is intended for use as an internal standard for the quantification of etomidate by GC- or LC-MS. | ||||
| GN10032 | Ginsenoside F1 | 53963-43-2 | >98.00% | |
Ginsenoside F1是从人参中提取的次级代谢产物，是人参皂苷Rg1的脱糖衍生物。 | ||||
| GN10137 | Galangin | 548-83-4 | >98.00% | |
A natural flavonoid | ||||
| GN10150 | Apigenin | 520-36-5 | >99.00% | |
芹菜素(Apigenin,API)是一种竞争性 CYP2C9 抑制剂,Ki 为2 µM。. | ||||
| GN10200 | Salvianolic acid C | 115841-09-3 | >98.00% | |
Salvianolic acid C 是一种非竞争性细胞色素 P4502C8 (CYP2C8) 抑制剂和细胞色素 P45022J2 (CYP2J2) 的中度混合抑制剂，对 CYP2C8 和 CYP2J2 的 Kis 分别为 4.82 μM 和 5.75 μM。 | ||||
| GN10241 | 5-Methoxypsoralen | 484-20-8 | >99.50% | |
A furanocoumarin derivative with diverse biological activities | ||||