Ferroptosis

ROS-generating agent 1（化合物2c）共价修饰TrxR的Sec-498残基生成ROS。

Tubulin inhibitor 30（化合物15）是一种微管蛋白组装抑制剂，IC50为0.52μM。

W1131 TFA是一种诱导铁下垂的强效STAT3抑制剂。

GPX4-IN-6（化合物C25）是GPX4共价抑制剂，IC50值为0.13 μM。

TfR-1-IN-1（化合物C4）是一种具有抗癌活性的转铁蛋白受体1 （TfR-1）抑制剂。

Ferroptosis-IN-6（化合物13）是一种有效的铁下垂抑制剂，EC50为25.5 nM。

Butylated hydroxytoluene-d3是氘标记的丁基化羟基甲苯。

FSP1的抑制剂

一种GPX4抑制剂

一种GPX4抑制剂

一种共价的GPX4抑制剂

N6F11 is a novel, selective and potent inducer of iron death with anticancer and antitumour activity that promotes GPX4 degradation by binding to TRIM25 in cancer cells.

GPX4 16 is an inhibitor of glutathione peroxidase 4 (GPX4).

FerroLOXIN-1 is an inhibitor of the 15-lipoxygenase-2 (15-LO-2) and phosphatidylethanolamine-binding protein 1 (PEBP1) catalytic complex.

Ferroptosis inducer 24 is an inducer of ferroptosis.

viFSP1 is a species-independent inhibitor of ferroptosis suppressor protein 1 (FSP1; IC50s = 34 and 83 nM for the human and mouse enzymes, respectively).

FA16 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter.

Ferroptosis Inhibitor D1是一种自由基清除剂和铁下垂抑制剂。

GPX4 Inhibitor 17是一种含二茂铁的谷胱甘肽过氧化物酶4 （GPX4）抑制剂和铁下垂诱导剂。

Baicalein（黄芩素；5，6，7-三羟基黄酮）是具有多种生物活性的黄酮类化合物，是黄嘌呤氧化酶抑制剂，IC 50 值为3.12μM。

Trigonelline是一种从 Trigonella foenum-graecum L 或 Leonurus artemisia 中分离出来的生物碱，是一种强效且特异性的Nrf2抑制剂。

Compound from Chinese traditional medicine with reported antifungal, anticancer actions

A phenol with diverse biological activities

Artemisinine是一种从青蒿植物（ Artemisia annua ）中提取的倍半萜内酯类抗疟药。