EGFR
EGFR(表皮生长因子受体)
EGFR (epidermal growth factor receptor) is the cell-surface receptor of its specific ligands, including epidermal growth factor and TGFα (transforming growth factor α) and is a receptor tyrosine kinase.
EGFR 相关产品(242)
- GC16021Lavendustin ACAS: 125697-92-9
A selective inhibitor of EGF receptor-associated tyrosine kinase
- GC17790CL-387785 (EKI-785)CAS: 194423-06-8纯度: >98.00%
An irreversible inhibitor of EGFR kinase activity
- GC19044Avitinib maleateCAS: 1557268-88-8纯度: >99.00%
Avitinib maleate是一种基于吡咯并嘧啶的不可逆表皮生长因子受体（EGFR）抑制剂，其IC 50 值为7.68nM。
- GC19218LazertinibCAS: 1903008-80-9纯度: >97.00% / >99.50% / >98.00%
Lazertinib是一种有效的、高度突变选择性的、能穿透血脑屏障的、口服的、不可逆的第三代EGFR酪氨酸激酶抑制剂。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC12864 | AG-1557 | 189290-58-2 | >99.50% | |
An EGFR inhibitor | ||||
| GC12955 | AZ5104 | 1421373-98-9 | >98.00% | |
An active metabolite of AZD 9291 | ||||
| GC13143 | AZD3759 | 1626387-80-1 | >99.50% | |
A brain penetrant inhibitor of EGFR | ||||
| GC13168 | AG 825 | 149092-50-2 | >98.00% | |
An inhibitor of Her2/Neu tyrosine kinase activity | ||||
| GC13213 | WZ3146 | 1214265-56-1 | >99.00% | |
An inhibitor of mutant EGFR | ||||
| GC14102 | Genistein | 446-72-0 | >99.50% | |
染料木黄酮是一种异黄酮，属于类黄酮化合物，存在于多种植物中。 | ||||
| GC14103 | NSC228155 | 113104-25-9 | >98.00% | |
An EGFR activator and inhibitor of KID-KIX interactions | ||||
| GC14494 | AG 99 | 122520-85-8 | >99.00% | |
An inhibitor of EGF receptor kinase | ||||
| GC15271 | Tyrphostin AG 879 | 148741-30-4 | >99.50% | |
A non-specific tyrphostin ErbB2 inhibitor | ||||
| GC15370 | Olmutinib (HM61713, BI 1482694) | 1353550-13-6 | >98.00% | |
An inhibitor of mutant EGFR | ||||
| GC15589 | WHI-P154 | 211555-04-3 | >99.00% | |
A JAK3 inhibitor | ||||
| GC15925 | PD 158780 | 171179-06-9 | >99.50% | |
An ErbB receptor family inhibitor | ||||
| GC15950 | CGP 52411 | 145915-58-8 | - | |
A phthalimide with diverse biological activities | ||||
| GC16000 | WHI-P180 | 211555-08-7 | >99.50% | |
A multi-kinase inhibitor | ||||
| GC16021 | Lavendustin A | 125697-92-9 | - | |
A selective inhibitor of EGF receptor-associated tyrosine kinase | ||||
| GC16321 | EGF816 | 1508250-71-2 | >99.00% | |
An inhibitor of mutant EGFR | ||||
| GC17790 | CL-387785 (EKI-785) | 194423-06-8 | >98.00% | |
An irreversible inhibitor of EGFR kinase activity | ||||
| GC17916 | Poziotinib | 1092364-38-9 | - | |
An inhibitor of EGFRs | ||||
| GC19044 | Avitinib maleate | 1557268-88-8 | >99.00% | |
Avitinib maleate是一种基于吡咯并嘧啶的不可逆表皮生长因子受体（EGFR）抑制剂，其IC 50 值为7.68nM。 | ||||
| GC19066 | BGB-283 | 1446090-77-2 | - | |
BGB-283 is a novel and potent Raf Kinase and EGFR inhibitor with IC50 values of 23 and 29 nM for recombinant BRafV600E and EGFR, respectively. | ||||
| GC19132 | EGFR-IN-3 | 1660963-42-7 | >99.00% | |
EGFR-IN-3 是第三代 EGFR TKI，GI50 值分别为 5 nM (EGFR L858R/T790M)、10 nM (EGFR del19) 和 689 nM (EGFR WT)。 EGFR-IN-3 具有用于 NSCLC 研究的潜力。 | ||||
| GC19218 | Lazertinib | 1903008-80-9 | >97.00% / >99.50% / >98.00% | |
Lazertinib是一种有效的、高度突变选择性的、能穿透血脑屏障的、口服的、不可逆的第三代EGFR酪氨酸激酶抑制剂。 | ||||
| GC19256 | MTX-211 | 1952236-05-3 | >98.00% | |
MTX-211 (Mol 211) 是 EGFR 和 PI3K 的双重抑制剂，IC50 值 <100 nM。 MTX-211可用于癌症和其他疾病的研究。 | ||||
| GC19364 | Tyrphostin AG 528 | 133550-49-9 | >98.00% | |
A tyrphostin that inhibits EGFR and HER2 | ||||