Reactive Oxygen Species
Reactive Oxygen Species(活性氧)
Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion.
ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.
Reactive Oxygen Species 相关产品(453)
- GC43316Coumarin Boronic AcidCAS: 1357078-03-5纯度: >99.50% / >95.00%
A fluorescent probe for direct detection of peroxynitrite
- GC43317Coumarin Boronic Acid pinacolate esterCAS: 190788-61-5纯度: >98.00%
A fluorescent probe for detection of peroxynitrite
- GC44301N-acetyl-L-Cysteine amideCAS: 38520-57-9纯度: >98.00%
N-乙酰-L-半胱氨酸酰胺 (NACA) 是一种新型抗氧化剂，它是 N-乙酰半胱氨酸 (NAC) 的酰胺形式，因为它可渗透细胞膜和线粒体膜 . N-乙酰半胱氨酸酰胺可透过细胞膜和线粒体膜，穿过血脑屏障，具有比NAC更高的自由基清除能力、金属螯合活性和还原能力。
- GC44589Pelargonidin (chloride)CAS: 134-04-3纯度: >98.00% / >95.00%
Pelargonidin (chloride)是一种花青素，具有抗氧化、抗炎、抗癌、神经保护等多种生物活性。Pelargonidin (chloride)能够抑制细胞色素P450家族1亚家族A成员1（CYP1A1）活性，IC 50 值为33μM。
- GC44594Pentafluorobenzenesulfonyl fluoresceinCAS: 728912-45-6纯度: >98.00%
A selective, fluorescent probe for H 2 O 2 detection
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC43316 | Coumarin Boronic Acid | 1357078-03-5 | >99.50% / >95.00% | |
A fluorescent probe for direct detection of peroxynitrite | ||||
| GC43317 | Coumarin Boronic Acid pinacolate ester | 190788-61-5 | >98.00% | |
A fluorescent probe for detection of peroxynitrite | ||||
| GC43335 | Cyanidin 3-O-arabinoside | 792868-19-0 | >98.00% | |
An anthocyanin antioxidant | ||||
| GC43352 | CYPMPO | 934182-09-9 | >95.00% | |
A novel spin trap for hydroxyl and superoxide radical detection | ||||
| GC43410 | DEPMPO | 157230-67-6 | >98.00% | |
A spin trap for superoxide radical detection | ||||
| GC43411 | DEPMPO-biotin | 936224-52-1 | >95.00% | |
A biotinylated spin trap | ||||
| GC43439 | Diallyl Trisulfide | 2050-87-5 | >98.00% | |
Diallyl Trisulfide是一种从大蒜中提取的有机硫化合物。 | ||||
| GC43462 | Dihydrolipoic Acid | 462-20-4 | >97.00% | |
A reduced form of α-lipoic acid | ||||
| GC43569 | DPPP | 110231-30-6 | >95.00% | |
A fluorescent probe for detection of hydroperoxides | ||||
| GC43656 | FBBBE | 1522117-83-4 | >95.00% | |
A fluorescent probe for intracellular H 2 O 2 production | ||||
| GC43870 | HPF | 359010-69-8 | >98.00% | |
A cell permeable, fluorescent dye for detection of highly reactive oxygen species | ||||
| GC44190 | MGR2 | 2361529-47-5 | >98.00% | |
A negative control for MGR1 | ||||
| GC44191 | MHY908 | 1393371-39-5 | >98.00% | |
A PPARα and PPARγ dual agonist | ||||
| GC44199 | MitoB | 1247025-84-8 | >95.00% | |
A probe to detect H 2 O 2 in mitochondria | ||||
| GC44201 | MitoP | 74597-01-6 | >95.00% | |
The end product of a mitochondrial matrix H 2 O 2 probe reaction | ||||
| GC44204 | MitoPQ | 1821370-28-8 | >98.00% | |
MitoPQ （ MitoParaquat）是一种可选择性增加体内和细胞线粒体基质内超氧化物产生的线粒体靶向氧化还原循环剂。 | ||||
| GC44205 | Mitoquinol | 845959-55-9 | >98.00% | |
A mitochondria-targeted antioxidant | ||||
| GC44301 | N-acetyl-L-Cysteine amide | 38520-57-9 | >98.00% | |
N-乙酰-L-半胱氨酸酰胺 (NACA) 是一种新型抗氧化剂，它是 N-乙酰半胱氨酸 (NAC) 的酰胺形式，因为它可渗透细胞膜和线粒体膜 . N-乙酰半胱氨酸酰胺可透过细胞膜和线粒体膜，穿过血脑屏障，具有比NAC更高的自由基清除能力、金属螯合活性和还原能力。 | ||||
| GC44589 | Pelargonidin (chloride) | 134-04-3 | >98.00% / >95.00% | |
Pelargonidin (chloride)是一种花青素，具有抗氧化、抗炎、抗癌、神经保护等多种生物活性。Pelargonidin (chloride)能够抑制细胞色素P450家族1亚家族A成员1（CYP1A1）活性，IC 50 值为33μM。 | ||||
| GC44594 | Pentafluorobenzenesulfonyl fluorescein | 728912-45-6 | >98.00% | |
A selective, fluorescent probe for H 2 O 2 detection | ||||
| GC44602 | Peroxynitrite | 14042-01-4 | >90.00% | |
体内NO与超氧化物反应生成过氧亚硝酸盐。 | ||||
| GC44670 | PPA | 13159-16-5 | >98.00% | |
The product of peroxidase-catalyzed reduction of PPHP | ||||
| GC44672 | PPHP | 87864-20-8 | >98.00% | |
A substrate used to quantitate peroxidase activity | ||||
| GC44860 | S1QEL1.1 | 897613-29-5 | >98.00% | |
A suppressor of I Q electron leak | ||||