Reactive Oxygen Species
Reactive Oxygen Species(活性氧)
Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion.
ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.
Reactive Oxygen Species 相关产品(453)
- GC44918SOTS-1 (technical grade)CAS: 223507-96-8纯度: >80.00%
A chemical source of superoxide anion in aqueous solution
- GC45059TMB (hydrochloride hydrate)CAS: 207738-08-7纯度: >98.00%
Chromogenic substrate for monitoring heme peroxidase activity
- GC45066Tosyl Phenylalanyl Chloromethyl KetoneCAS: 402-71-1纯度: >97.00%
An inhibitor of chymotrypsin-like serine proteases
- GC45131Urotensin II (human) (trifluoroacetate salt)纯度: >95.00%
A neuropeptide agonist of the urotensin II receptor
- GC45226β-BHCCAS: 319-85-7纯度: 95.00%
β-BHC is an isomer of the organochlorine pesticide γ-lindane that is a potential impurity found in commercial preparations of lindane.
- GC453373-HydroxyterphenyllinCAS: 66163-76-6纯度: >70.00%
A fungal metabolite with diverse biological activities
- GC45379Alloxan (hydrate)CAS: 2244-11-3纯度: >98.00%
A toxin that selectively eliminates pancreatic β-cells
- GC45777Peonidin 3-O-glucoside (chloride)CAS: 6906-39-4纯度: >98.00%
An anthocyanin with diverse biological activities
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC44918 | SOTS-1 (technical grade) | 223507-96-8 | >80.00% | |
A chemical source of superoxide anion in aqueous solution | ||||
| GC44947 | SRS16-86 | 1793052-96-6 | >98.00% | |
SRS16-86是一种第三代ferrostatin类铁死亡抑制剂。 | ||||
| GC44989 | TAN 420E | 91700-93-5 | >95.00% | |
A bacterial metabolite | ||||
| GC45010 | TEMPONE | 2896-70-0 | >98.00% | |
A 4-oxo derivative of the spin trap TEMPO | ||||
| GC45059 | TMB (hydrochloride hydrate) | 207738-08-7 | >98.00% | |
Chromogenic substrate for monitoring heme peroxidase activity | ||||
| GC45066 | Tosyl Phenylalanyl Chloromethyl Ketone | 402-71-1 | >97.00% | |
An inhibitor of chymotrypsin-like serine proteases | ||||
| GC45131 | Urotensin II (human) (trifluoroacetate salt) | - | >95.00% | |
A neuropeptide agonist of the urotensin II receptor | ||||
| GC45226 | β-BHC | 319-85-7 | 95.00% | |
β-BHC is an isomer of the organochlorine pesticide γ-lindane that is a potential impurity found in commercial preparations of lindane. | ||||
| GC45248 | (-)-FINO2 | 869298-31-7 | >98.00% | |
(-)-FINO2一种能够选择性激活铁死亡的有机过氧化物，用于研究铁死亡机制及抗肿瘤治疗 | ||||
| GC45337 | 3-Hydroxyterphenyllin | 66163-76-6 | >70.00% | |
A fungal metabolite with diverse biological activities | ||||
| GC45357 | 5-Chlorouracil | 1820-81-1 | >98.00% | |
A chlorinated derivative of uracil | ||||
| GC45379 | Alloxan (hydrate) | 2244-11-3 | >98.00% | |
A toxin that selectively eliminates pancreatic β-cells | ||||
| GC45513 | MGR1 | 2361529-46-4 | >98.00% | |
A ROS-generating probe | ||||
| GC45578 | Thymohydroquinone | 2217-60-9 | >98.00% | |
A quinone with diverse biological activities | ||||
| GC45595 | Vulpinic Acid | 521-52-8 | >98.00% | |
A lichen metabolite with diverse biological activities | ||||
| GC45662 | Dieugenol | 4433-08-3 | >98.00% | |
A neolignan with antioxidative and antiparasitic activities | ||||
| GC45706 | GHK-Cu (acetate) | 300801-03-0 | >98.00% | |
A tripeptide-copper(II) complex | ||||
| GC45777 | Peonidin 3-O-glucoside (chloride) | 6906-39-4 | >98.00% | |
An anthocyanin with diverse biological activities | ||||
| GC45820 | Balsalazide-d4 | - | >99.00% | |
Balsalazide-d4 是氘标记的 Balsalazide。 | ||||
| GC45877 | CYM 5478 | 870762-83-7 | >98.00% | |
An S1P 2 agonist | ||||
| GC45917 | Leucettine L41 | 1112978-84-3 | >98.00% | |
An inhibitor of DYRK1A, DYRK2, CLK1, and CLK3 | ||||
| GC46005 | Arjunolic Acid | 465-00-9 | >98.50% | |
A triterpene with diverse biological activities | ||||
| GC46019 | Pluviatolide | 28115-68-6 | >95.00% | |
A lignan | ||||
| GC46028 | Malabaricone C | 63335-25-1 | >98.00% | |
A diarylnonanoid with diverse biological activities | ||||