GlpBio

Reactive Oxygen Species

Reactive Oxygen Species(活性氧)

Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion.

ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.

Reactive Oxygen Species 相关产品(453)

  • GC92043 structure
    GC920439(10)-Nitrooleate
    CAS: 1092676-99-7
    纯度: >95.00%

    9(10)-Nitrooleate是一种硝基烯内源性脂质信号分子9-硝基油酸酯的混合物。

  • GC92088 structure
    GC92088GLP-1 (28-36) amide (trifluoroacetate salt)
    纯度: >98.00%

    胰高血糖素样肽1GLP-1 (28-36) amide (trifluoroacetate salt)是内源性GLP-1R激动剂GLP-1（7-36）酰胺的肽和活性代谢产物。

  • GN10006 structure
    GN100063,4-Dihydroxybenzaldehyde
    CAS: 139-85-5
    纯度: >99.50%

    A polyphenol with diverse biological activities

  • GN10041 structure
    GN10041Isoquercitrin
    CAS: 21637-25-2
    纯度: >98.50%

    A natural flavonoid and antioxidant

  • GN10074 structure
    GN10074Xanthotoxol
    CAS: 2009-24-7
    纯度: >98.00%

    A coumarin with diverse biological activities

  • GN10098 structure
    GN10098Glabridin
    CAS: 59870-68-7
    纯度: >97.00%

    A natural isoflavonoid with diverse actions

  • GN10120 structure
    GN10120Pinocembrin
    CAS: 480-39-7
    纯度: >98.00% / >99.00%

    Pinocembrin是一种黄酮类化合物，是竞争性的组氨酸脱羧酶（HDC）抑制剂。

  • GN10132 structure
    GN10132Schizandrin B
    CAS: 61281-37-6
    纯度: >98.00%

    A dibenzocyclooctadiene with diverse biological activities

  • GN10208 structure
    GN10208Berberine hydrochloride
    CAS: 633-65-8
    纯度: >98.00%

    盐酸小檗碱是来源于毛茛科药用植物黄连的一种异喹啉类生物碱，具有抗肿瘤、抗炎、降血糖等多种药理活性。

  • GN10221 structure
    GN10221Berberine
    CAS: 2086-83-1
    纯度: >98.00% / >99.50%

    小檗碱（Natural Yellow 18）是一种从中草药黄连中分离出来的生物碱，作为一种抗生素。

  • GN10237 structure
    GN10237Protopine
    CAS: 130-86-9
    纯度: >99.50%

    Protopine是一种从延胡索中提取的生物碱，可抑制乙酰胆碱酯酶活性（IC 50 =50μM）。

  • GN10264 structure
    GN10264Isochlorogenic acid A
    CAS: 2450-53-5
    纯度: >98.00%

    A natural phenolic compound with diverse biological activities

  • GN10276 structure
    GN10276Naringenin
    CAS: 480-41-1
    纯度: >98.50%

    Naringenin是一种柑橘类黄酮化合物，能够用于治疗癌症，具有抗氧化和抗炎活性。

  • GN10292 structure
    GN10292Silibinin
    CAS: 22888-70-6

    Silibinin是一种具有口服活性的类黄酮，具有保肝和抗癌作用。

  • GN10298 structure
    GN10298Alibiflorin
    CAS: 39011-90-0
    纯度: >98.00%

    A monoterpene glycoside with diverse biological activities

  • GN10308 structure
    GN10308Chlorogenic acid
    CAS: 327-97-9
    纯度: >98.00%

    Chlorogenic acid是一种有效的神经保护剂，同时具有抗病毒、抗真菌、抗氧化和抗肿瘤作用。Chlorogenic acid还参与调节葡萄糖和脂质代谢，改善胰岛素敏感性。

  • GN10325 structure
    GN10325Nobiletin
    CAS: 478-01-3
    纯度: >99.00%

    Nobiletin是从柑橘类植物中提取的一种多甲氧基黄酮类化合物。Nobiletin具有抗氧化、抗炎、抗肿瘤等多种药理作用。

  • GN10356 structure
    GN10356Calycosin-7-glucoside
    CAS: 20633-67-4
    纯度: >98.00%

    An isoflavone glycoside with diverse biological activities

  • GN10388 structure
    GN10388Gallic acid
    CAS: 149-91-7
    纯度: >99.50% / >99.00%

    A phenol with diverse biological activities

  • GN10422 structure
    GN10422Echinacoside
    CAS: 82854-37-3
    纯度: >98.00%

    Echinacoside是一种从 Cistanche tubulosa 中分离的，具有强效抗氧化和抗炎作用的苯乙醇类化合物。

  • GN10423 structure
    GN10423Lipoic acid
    CAS: 62-46-4
    纯度: >99.50%

    硫辛酸 ((R)-(+)-α-硫辛酸) 是一种抗氧化剂，是线粒体酶复合物的重要辅助因子。

  • GN10448 structure
    GN10448Lycopene
    CAS: 502-65-8
    纯度: >98.00% / >95.00% / >90.00%

    番茄红素（Lycopene）是一种脂溶性类胡萝卜素分子，在红色水果和蔬菜中含量很高，具有强大的抗氧化作用。

  • GN10475 structure
    GN10475Rhein
    CAS: 478-43-3
    纯度: >98.00%

    An anthraquinone derivative

  • GN10484 structure
    GN10484Amentoflavone
    CAS: 1617-53-4
    纯度: >98.00%

    A biflavonoid with diverse biological activities