GlpBio

Cyclin-Dependent Kinases

Cyclin-Dependent Kinases(细胞周期蛋白依赖性激酶)

Cyclin-dependent kinases is a group of serine/threonine kinases. It is activated by binding to cyclin and participates in the regulation of cell cycle.

Cyclin-Dependent Kinases 相关产品(69)

  • GC13649 structure
    GC13649Arcyriaflavin A
    CAS: 118458-54-1

    A CDK4 and CAMKII inhibitor

  • GC13690 structure
    GC13690BS-181 HCl
    CAS: 1397219-81-6
    纯度: >99.00%

    A selective Cdk7 inhibitor

  • GC13998 structure
    GC13998AT7519 Hydrochloride
    CAS: 902135-91-5
    纯度: >99.00%

    A Cdk inhibitor

  • GC14002 structure
    GC14002Bohemine
    CAS: 189232-42-6
    纯度: >98.00%

    A Cdk inhibitor

  • GC14182 structure
    GC14182Kenpaullone
    CAS: 142273-20-9
    纯度: >98.00%

    A inhibitor of cyclin-dependent kinase and GSK3β

  • GC14230 structure
    GC14230K03861
    CAS: 853299-07-7
    纯度: >98.00%

    K03861 (K03861) 是一种 II 型 CDK2 抑制剂，Kd 为 8.2 nM。 K03861 (K03861) 通过与活化细胞周期蛋白的结合竞争抑制 CDK2 活性。

  • GC14294 structure
    GC14294Cdk1/2 Inhibitor III
    CAS: 443798-47-8
    纯度: >98.50%

    A cell-permeable inhibitor of Cdk1 and Cdk2

  • GC14650 structure
    GC14650CGP60474
    CAS: 164658-13-3
    纯度: >98.50%

    A CDK inhibitor

  • GC14707 structure
    GC14707Purvalanol A
    CAS: 212844-53-6
    纯度: >99.00%

    A selective inhibitor of cyclin-dependent kinases

  • GC15047 structure
    GC15047PHA-793887
    CAS: 718630-59-2
    纯度: >98.00%

    A CDK inhibitor

  • GC15173 structure
    GC15173PD 0332991 (Palbociclib)
    CAS: 571190-30-2
    纯度: >99.50%

    PD 0332991 (Palbociclib) (PD 0332991) 是一种具有口服活性的选择性 CDK4 和 CDK6 抑制剂，IC50 值分别为 11 和 16 nM。 PD 0332991 (Palbociclib) 具有有效的抗增殖活性，可诱导癌细胞的细胞周期停滞，可用于 HR 阳性和 HER2 阴性乳腺癌和肝细胞癌的研究。

  • GC15215 structure
    GC15215Iso-Olomoucine
    CAS: 101622-50-8
    纯度: >98.00%

    An inactive stereoisomer of olomoucine

  • GC15421 structure
    GC15421Palbociclib (PD0332991) Isethionate
    CAS: 827022-33-3
    纯度: >99.50% / >98.00%

    Palbociclib (PD 0332991) isethionate 是一种具有口服活性的选择性 CDK4 和 CDK6 抑制剂，IC50 值分别为 11 和 16 nM。 Palbociclib (PD0332991) Isethionate 具有有效的抗增殖活性，可诱导癌细胞的细胞周期停滞，可用于 HR 阳性和 HER2 阴性乳腺癌和肝细胞癌的研究。

  • GC15588 structure
    GC15588PHA-848125
    CAS: 802539-81-7
    纯度: >99.50%

    An inhibitor of Cdks

  • GC15597 structure
    GC15597AT7519 trifluoroacetate
    CAS: 1431697-85-6
    纯度: >98.00%

    AT7519 (AT7519M) TFA 作为一种有效的 CDK 抑制剂，对 CDK1、CDK2、CDK4 到 CDK6 和 CDK9 的 IC50 分别为 210、47、100、13、170 和 <10 nM。

  • GC15607 structure
    GC15607ON123300
    CAS: 1357470-29-1
    纯度: >99.00%

    A multi-kinase inhibitor

  • GC15841 structure
    GC15841Alsterpaullone
    CAS: 237430-03-4
    纯度: >98.00%

    A dual CDK and GSK3 inhibitor

  • GC15870 structure
    GC15870AT7519
    CAS: 844442-38-2
    纯度: >99.50%

    A Cdk inhibitor

  • GC16063 structure
    GC16063Flavopiridol
    CAS: 146426-40-6
    纯度: >98.00%

    An inhibitor of cyclin-dependent kinases

  • GC16268 structure
    GC16268Purvalanol B
    CAS: 212844-54-7
    纯度: >98.50%

    A CDK inhibitor

  • GC16413 structure
    GC16413TMCB
    CAS: 905105-89-7
    纯度: >98.00%

    A dual inhibitor of CK2 and ERK8

  • GC16420 structure
    GC16420THZ531
    CAS: 1702809-17-3
    纯度: >98.00%

    An inhibitor of Cdk12 and Cdk13

  • GC16425 structure
    GC16425Flavopiridol hydrochloride
    CAS: 131740-09-5
    纯度: >98.00%

    An inhibitor of cyclin-dependent kinases

  • GC16429 structure
    GC16429(R)-DRF053 dihydrochloride
    CAS: 1241675-76-2

    cdk/CK1 inhibitor,potent and ATP-competitive