GlpBio

COX

COX(环氧合酶)

COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.

COX 相关产品(291)

  • GC70553 structure
    GC70553Pelubiprofen
    CAS: 69956-77-0
    纯度: >99.00%

    Pelubiprofen是一种口服活性非甾体抗炎药，属于2-芳基丙酸家族，对COX-2活性具有相对选择性的作用。

  • GC70778 structure
    GC70778Indazole-Cl
    CAS: 848142-62-1
    纯度: 不显示

    Indazole-Cl（Ind-Cl）是一种具有炎症作用的雌激素受体（ER）-β特异性激动剂。

  • GC71602 structure
    GC71602Propyphenazone-d3
    CAS: 162935-29-7
    纯度: >99.00%

    Propyphenazone-d3是氘标记的苯丙酮。

  • GC72794 structure
    GC72794Flobufen
    CAS: 112344-52-2
    纯度: 不显示

    Flobufen（VUFB 16066）是一种非甾体抗炎药和环氧化酶（COX）和5-脂氧合酶（5-LOX）抑制剂。

  • GC74187 structure
    GC74187Salicylic acid-13C6
    CAS: 1189678-81-6
    纯度: >97.00%

    Salicylic acid-13C6是13c标记的水杨酸。

  • GC90889 structure
    GC908895-(3'-Hydroxyphenyl)-γ-Valerolactone
    CAS: 21618-91-7
    纯度: >95.00%

    多种多酚的代谢产物。

  • GC91680 structure
    GC916804-Acetamido Antipyrine
    CAS: 83-15-8
    纯度: >95.00%

    4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole .

  • GC91681 structure
    GC91681Loxoprofen-SRS
    CAS: 83648-76-4
    纯度: >98.00%

    Loxoprofen-SRS is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.5 and 0.39 for recombinant human COX-1 and COX-2, respectively) and an active metabolite of the prodrug loxoprofen .

  • GN10004 structure
    GN10004EsculentosideA
    CAS: 65497-07-6
    纯度: >99.50%

    EsculentosideA (EsA)，一种从商陆根中分离得到的三萜皂苷。

  • GN10022 structure
    GN10022luteolin-6-C-glucoside
    CAS: 4261-42-1
    纯度: >98.00%

    A flavonoid with diverse biological activities

  • GN10039 structure
    GN10039Rutaecarpine
    CAS: 84-26-4
    纯度: >98.00%

    Rutaecarpine是一种从吴茱萸中分离出的吲哚并吡啶喹唑啉生物碱，已知在细胞水平上以0.28μM的IC 50 抑制COX-2。

  • GN10080 structure
    GN10080Byakangelicol
    CAS: 26091-79-2
    纯度: >98.00%

    A furanocoumarin with diverse biological activities

  • GN10220 structure
    GN10220Ginsenoside Rb3
    CAS: 68406-26-8
    纯度: >98.00%

    A steroid glycoside with diverse biological activities

  • GN10388 structure
    GN10388Gallic acid
    CAS: 149-91-7
    纯度: >99.50% / >99.00%

    A phenol with diverse biological activities

  • GN10395 structure
    GN10395Prim-O-glucosylcimifugin
    CAS: 80681-45-4
    纯度: >98.00%

    A chromone with diverse biological activities

  • GN10429 structure
    GN10429Neochlorogenic acid
    CAS: 906-33-2
    纯度: >98.00%

    A phenolic compound with diverse biological activities

  • GN10430 structure
    GN10430D-(-)-Salicin
    CAS: 138-52-3
    纯度: >99.00%

    A non-selective COX inhibitor

  • GN10549 structure
    GN10549Ginsenoside Rd
    CAS: 52705-93-8
    纯度: >98.00%

    A natural steroid glycoside with diverse effects

  • GN10605 structure
    GN10605(+)-Catechin hydrate
    CAS: 225937-10-0
    纯度: >99.50%

    A polyphenolic flavonoid with diverse biological activities

  • GN10645 structure
    GN10645Jaceosidin
    CAS: 18085-97-7

    A natural methylated trihydroxyflavone

  • GN10685 structure
    GN10685Anemarsaponin B
    CAS: 139051-27-7

    Anemarsaponin B 是一种甾体皂苷。

  • GN10799 structure
    GN1079920(S)-Ginsenoside Rg3
    CAS: 14197-60-5
    纯度: >98.00%

    20(S)-Ginsenoside Rg3是从人参中提取的稀有人参皂苷（Na + ：IC 50 = 32.2±4.5μM；hKv1.4：IC 50 = 32.6±2.2μM）。

  • GC15179 structure
    GC15179Ketorolac
    CAS: 74103-06-3

    An NSAID and COX inhibitor

  • GC11090 structure
    GC11090Diclofenac
    CAS: 15307-86-5
    纯度: >99.50%

    Diclofenac是一种强效的非选择性环氧化酶（COX）抑制剂，在CHO细胞中对人源COX-1和COX-2的IC₅₀值分别为4nM和1.3nM；对羊源COX-1和COX-2的IC₅₀值分别为5.1μM和0.84μM。