GlpBio

Anemarsaponin B

目录号: GN10685纯度: >98%同义词: 知母皂苷 B
COASDSData Sheet
Anemarsaponin B 是一种甾体皂苷。
Anemarsaponin B
Cas No.: 139051-27-7
规格价格库存数量操作
20mg¥3,108.00现货
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产品描述 Description

Anemarsaponin B is a steroidal saponin isolated from the rhizomes of A. asphodeloides (Liliaceae). Anemarsaponin B decreases the protein and mRNA levels of iNOS and COX-2. Anemarsaponin B reduces the expressions and productions of pro-inflammatory cytokines, including TNF-a and IL-6. Anemarsaponin B inhibits the nuclear translocation of the p65 subunit of NF-κB by blocking the phosphorylation of IκBα. Anemarsaponin B also inhibits the phosphorylation of MAP kinase kinases 3/6 (MKK3/6) and mixed lineage kinase 3 (MLK3). Anti-inflammatory effect [1].

References:
[1]. Kim JY, et al. Anti-inflammatory effect of anemarsaponin B isolated from the rhizomes of Anemarrhena asphodeloides in LPS-induced RAW 264.7 macrophages is mediated by negative regulation of the nuclear factor-kappaB and p38 pathways. Food Chem Toxicol. 2009 Jul;47(7):1610-7.

产品文档 Product Documents

Purity:>98%
COASDSData Sheet

化学性质Chemical Properties

CAS 号
139051-27-7
同义词
知母皂苷 B
化学名
(2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(((6aS,8aS,8bS,11aS)-6a,8a,9-trimethyl-10-(3-methyl-4-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)butyl)-2,2a,3,4,5,6,6a,6b,7,8,8a,8b,11a,12,12a,
SMILES
CC(CO[C@@]1([H])[C@@](O)([H])[C@](O)([H])[C@@](O)([H])[C@@](O1)([H])CO)([H])CCC(O2)=C([C@@]3([H])[C@]2([H])CC4([H])C(C5([H])CC[C@@]43C)([H])CCC6([H])CC(O[C@@]7([H])[C@@](O[C@@]8([H])[C@@](O)([H])[C@](O)([H])[C@@](O)([H])[C@@](O8)([H])CO)([H])[C@](O)([H])[
分子式
C45H74O18
分子量
903.06 g/mol
溶解性
≥ 8.77mg/mL in EtOH with ultrasonic and warming
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

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g/mol