Other Apoptosis
Other Apoptosis(其他细胞凋亡)
Other Apoptosis 相关产品(883)
- GC19306RAD51 Inhibitor B02CAS: 1290541-46-6纯度: >99.50%
RAD51 Inhibitor B02是一种人RAD51重组酶的特异性抑制剂（IC 50 值为27.4μM），对大肠杆菌中的同系物RecA没有抑制作用（IC 50 >250μM）。
- GC19541(rac)-Antineoplaston A10CAS: 77658-84-5
(rac)-Antineoplaston A10 是 Antineoplaston A10 的外消旋体。 Antineoplaston A10 是一种潜在的 Ras 抑制剂，可用于治疗神经胶质瘤、淋巴瘤、星形细胞瘤和乳腺癌。
- GC25428Foscenvivint (ICG-001)CAS: 780757-88-2 (relative stereochemistry); 847591-62-2 (absolute stereochemistry)
Foscenvivint (ICG-001) antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to CREB-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300. ICG-001 induces apoptosis.
- GC25691OTS514 hydrochlorideCAS: 2319647-76-0
OTS514 is a highly potent TOPK(T-LAK cell-originated protein kinase) inhibitor with an IC50 value of 2.6 nM. OTS514 induces cell cycle arrest and apoptosis.
- GC25743PIM447 (LGH447)CAS: 1210608-43-7(freebase)
PIM447 (LGH447) is a novel pan-PIM kinase inhibitor with Ki values of 6 pM, 18 pM, 9 pM for PIM1, PIM2, PIM3 respectively. It also inhibits GSK3β, PKN1, and PKCτ, but at a significantly lower potency with IC50 between 1 and 5 μM (>105-fold differential relative to the Ki on PIMs). PIM447 induces apoptosis.
- GC30110Oleic acid (9-cis-Octadecenoic acid)CAS: 112-80-1纯度: >98.00%
油酸（9-顺式-十八碳烯酸）是一种单不饱和的Omega-9脂肪酸，存在于植物和动物中。
- GC30205S-Allyl-L-cysteineCAS: 21593-77-1纯度: >97.00%
A water soluble organosulfur compound derived from garlic
- GC30240Calcium dobesilateCAS: 20123-80-2纯度: >98.00%
Calcium dobesilate (calcium dihydroxy-2,5-benzenesulfonate) is a small molecule that has been widely used for treating diabetic retinopathy and chronic venous insufficiency.
- GC30266L-SelenoMethionineCAS: 3211-76-5纯度: >99.50% / >98.00%
L-SelenoMethionine是一种硒氨基酸，作为膳食中的天然成分，约占日常硒摄入量的50%以上。
- GC30788L-Glutamic acid monosodium salt (Monosodium glutamate)CAS: 142-47-2纯度: >98.00% / >99.50%
L-Glutamic acid monosodium salt is the sodium salt of glutamic acid, found naturally in tomatoes, cheese and other foods. L-Glutamic acid monosodium salt acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). (S)-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
- GC31186Citicoline sodium saltCAS: 33818-15-4纯度: >99.50%
Citicoline sodium salt是胞磷胆碱的水溶性形式，胞磷胆碱是磷脂酰胆碱合成过程中的天然中间体，作为乙酰胆碱和磷脂酰胆碱在大脑中的前体，具有抑制活性氧（ROS）产生和细胞凋亡的生物学功能。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC19215 | KRIBB11 | 342639-96-7 | >98.00% | |
An Hsf1 inhibitor | ||||
| GC19248 | Mivebresib | 1445993-26-9 | >99.00% | |
A BRD2, BRD4, and BRDT inhibitor | ||||
| GC19263 | NKP-1339 | 197723-00-5 | >98.00% | |
A ruthenium complex with anticancer activity | ||||
| GC19290 | PF-3084014 | 1290543-63-3 | >98.00% | |
An inhibitor of γ-secretase | ||||
| GC19293 | PFK-158 | 1462249-75-7 | >98.00% | |
PFK-158 是一种有效的选择性 PFKFB3 抑制剂，通过减少癌细胞中葡萄糖的摄取、ATP 的产生、乳酸的释放以及诱导细胞凋亡和自噬，显示出广泛的抗肿瘤活性.PFK-158 在 EC 细胞中以剂量和时间依赖性方式抑制细胞活力。 | ||||
| GC19306 | RAD51 Inhibitor B02 | 1290541-46-6 | >99.50% | |
RAD51 Inhibitor B02是一种人RAD51重组酶的特异性抑制剂（IC 50 值为27.4μM），对大肠杆菌中的同系物RecA没有抑制作用（IC 50 >250μM）。 | ||||
| GC19346 | Talampanel | 161832-65-1 | >98.00% | |
An allosteric AMPA receptor antagonist | ||||
| GC19398 | PIM447 | 1210608-43-7 | - | |
PIM447 (LGH447) 是一种有效的、口服的、选择性的泛 PIM 激酶抑制剂，对 PIM1、PIM2 和 PIM3 的 Ki 值分别为 6、18 和 9 pM。 PIM447 具有双重抗骨髓瘤和骨保护作用。 PIM447 诱导细胞凋亡。 | ||||
| GC19411 | IITZ-01 | 1807988-47-1 | >99.00% | |
IITZ-01 是一种有效的溶酶体自噬抑制剂，具有单剂抗肿瘤活性，对 PI3Kγ 的 IC50 为 2.62 μM。 | ||||
| GC19436 | CID-5721353 | 301356-95-6 | >98.00% | |
A Bcl-6 inhibitor | ||||
| GC19457 | Trolox | 53188-07-1 | >98.00% | |
Vitamin E derivative with antioxidant properties | ||||
| GC19485 | DC661 | 1872387-43-3 | >98.00% | |
DC661是一种能够抑制棕榈酰蛋白硫酯酶1（PPT1）并有效抑制细胞自噬的小分子化合物，可作为抗溶酶体剂。 | ||||
| GC19541 | (rac)-Antineoplaston A10 | 77658-84-5 | - | |
(rac)-Antineoplaston A10 是 Antineoplaston A10 的外消旋体。 Antineoplaston A10 是一种潜在的 Ras 抑制剂，可用于治疗神经胶质瘤、淋巴瘤、星形细胞瘤和乳腺癌。 | ||||
| GC25428 | Foscenvivint (ICG-001) | 780757-88-2 (relative stereochemistry); 847591-62-2 (absolute stereochemistry) | - | |
Foscenvivint (ICG-001) antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to CREB-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300. ICG-001 induces apoptosis. | ||||
| GC25691 | OTS514 hydrochloride | 2319647-76-0 | - | |
OTS514 is a highly potent TOPK(T-LAK cell-originated protein kinase) inhibitor with an IC50 value of 2.6 nM. OTS514 induces cell cycle arrest and apoptosis. | ||||
| GC25743 | PIM447 (LGH447) | 1210608-43-7(freebase) | - | |
PIM447 (LGH447) is a novel pan-PIM kinase inhibitor with Ki values of 6 pM, 18 pM, 9 pM for PIM1, PIM2, PIM3 respectively. It also inhibits GSK3β, PKN1, and PKCτ, but at a significantly lower potency with IC50 between 1 and 5 μM (>105-fold differential relative to the Ki on PIMs). PIM447 induces apoptosis. | ||||
| GC30085 | Neobavaisoflavone | 41060-15-5 | >98.00% | |
A natural isoflavone | ||||
| GC30110 | Oleic acid (9-cis-Octadecenoic acid) | 112-80-1 | >98.00% | |
油酸（9-顺式-十八碳烯酸）是一种单不饱和的Omega-9脂肪酸，存在于植物和动物中。 | ||||
| GC30205 | S-Allyl-L-cysteine | 21593-77-1 | >97.00% | |
A water soluble organosulfur compound derived from garlic | ||||
| GC30240 | Calcium dobesilate | 20123-80-2 | >98.00% | |
Calcium dobesilate (calcium dihydroxy-2,5-benzenesulfonate) is a small molecule that has been widely used for treating diabetic retinopathy and chronic venous insufficiency. | ||||
| GC30266 | L-SelenoMethionine | 3211-76-5 | >99.50% / >98.00% | |
L-SelenoMethionine是一种硒氨基酸，作为膳食中的天然成分，约占日常硒摄入量的50%以上。 | ||||
| GC30788 | L-Glutamic acid monosodium salt (Monosodium glutamate) | 142-47-2 | >98.00% / >99.50% | |
L-Glutamic acid monosodium salt is the sodium salt of glutamic acid, found naturally in tomatoes, cheese and other foods. L-Glutamic acid monosodium salt acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). (S)-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals. | ||||
| GC30896 | 4-Hydroxybenzyl alcohol | 623-05-2 | - | |
A phenol with diverse biological activities | ||||
| GC31186 | Citicoline sodium salt | 33818-15-4 | >99.50% | |
Citicoline sodium salt是胞磷胆碱的水溶性形式，胞磷胆碱是磷脂酰胆碱合成过程中的天然中间体，作为乙酰胆碱和磷脂酰胆碱在大脑中的前体，具有抑制活性氧（ROS）产生和细胞凋亡的生物学功能。 | ||||