Famoxadone is a fungicide.1 It inhibits mitochondrial complex III, also known as the cytochrome bc1 complex, and electron transport in rat heart submitochondria (IC50s = 28 and 4.5 ng/ml, respectively). It reduces oxygen consumption in, and induces disintegration of, P. infestans zoospores when used at a concentration of 2 ?g/ml. Famoxadone inhibits the growth of P. viticola on grape seedlings (EC50 = 3 ?g/ml). Formulations containing famoxadone have been used to control various fungal diseases in crops.
1.Jordan, D.B., Livingston, R.S., Bisaha, J.J., et al.Mode of action of famoxadonePestic. Sci.55105-118(1999)