Tiaprost (Iliren)

目录号: GC31445纯度: >98%同义词: 噻前列素,Iliren

A synthetic analog of PGF_2α

Cas No.: 71116-82-0

规格	价格	库存	数量	操作
1mg	¥1,244.00	现货	1

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610, 366–372 (2022)
Cell
187(9):2288-2304 (2024)
Cell
183(7):1867-1883 (2020)
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388(6745) (2025)
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387(6739) (2025)
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387(6734) (2025)
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产品描述 Description

Prostaglandin F_2α plays a central role in luteolysis. Tiaprost is a synthetic analog of PGF_2α that is used in veterinary medicine as an estrus-synchronizing agent.¹ It has also been used to treat endometritis and to induce parturition.^2,3

1.Yadav, V.K., Sudhagar, R.R., and Medhamurthy, R.Apoptosis during spontaneous and prostaglandin F2α-induced luteal regression in the buffalo cow (Bubalus bubalis): Involvement of mitogen-activated protein kinasesBiol. Reprod.67752-759(2002) 2.Sheldon, I.M., Lewis, G.S., LeBlanc, S., et al.Defining postpartum uterine disease in cattleTheriogenology651516-1530(2006) 3.Holtz, W., Schmidt-Baulain, R., Meyer, H., et al.Control of prostaglandin-induced parturition in sows by injection of theβadrenergic blocking agent carazolol or carazolol and oxytocinJ. Anim. Sci.683967-3971(1990)

实验参考方法 Experimental Reference Method

Animal experiment:

Cows[1]Six healthy dairy cows of the German Black Pied breed, pregnant for 190 to 266 days, are treated initially with 0.75 mg of the PGF2α analog Tiaprost SC (treatment day=day 0). All animals are moved to the department’s large animal hospital 5 to 20 days before treatment commenced; they are kept in stanchions and fed. All animals are examined clinically daily and rectally as well as vaginally at two- to six-day intervals[1].

References:

[1]. Grunert E, et al. Delayed termination of third-trimester gestations in dairy cows after treatment with the PGF(2alpha)analog Tiaprost. Theriogenology. 1984 May;21(5):823-34.

产品文档 Product Documents

Purity:>98%

COA SDS Data Sheet

化学性质Chemical Properties

CAS 号

71116-82-0

同义词

噻前列素,Iliren

SMILES

O=C(O)CCC/C=C/CC1C(/C=C/C(O)COC2=CSC=C2)C(O)CC1O

分子式

C₂₀H₂₈O₆S

分子量

396.5 g/mol

溶解性

DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 2 mg/ml

保存条件

Store at -20°C

General tips

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。

Shipping Condition

评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

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