GlpBio

Sulochrin

目录号: GC18453纯度: >98.00%同义词: 硫赭曲菌素
A fungal metabolite with antiallergenic, anti-angiogenic, and antiviral activity
Sulochrin
Cas No.: 519-57-3
规格价格库存数量操作
1mg¥2,988.00现货
1
5mg¥11,150.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

Sulochrin is a fungal metabolite produced by A. terreus and Penicillium that exhibits antiallergenic, anti-angiogenic, and antiviral activities. Sulochrin inhibits eosinophil degranulation. It prevents leukotriene C4 (LTC4) release, O2- production, and IL-8 production (IC50s = 0.03, 8.2, 9.6, and 8.7 μM, respectively) and inhibits migration of human and guinea pig eosinophils (IC50 = 0.2-0.4 μM). Sulochrin inhibits VEGF-induced capillary tube formation of human umbilical vein endothelial cells (HUVEC) in vitro (70% inhibition at 10 mg/ml). It also inhibits hepatitis C viral infection (IC50 = 24.4 μM) in vitro.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
519-57-3
同义词
硫赭曲菌素
化学名
2-(2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxy-benzoic acid, methyl ester
SMILES
O=C(C1=C(OC)C=C(O)C=C1C(OC)=O)C2=C(O)C=C(C)C=C2O
分子式
C17H16O7
分子量
332.3 g/mol
溶解性
DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol