关于 "Cytoskeleton & Motor Proteins" 的结果261+ 个结果
- HIV-1 tat Protein (47-57) amideCAS: 697226-52-1
HIV-1 tat Protein (47-57) is a potent cell penetrating peptides.
- Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) (TFA)
Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) TFA,具有 20 个残基肽,也是主要的致病表位,存在于光受体间类视黄醇结合蛋白肽 (IRBP 161-180) 的第一个同源重复中, 可引起后葡萄膜炎 (EAU)。
- Aminopeptidase N/APN Protein, Human (HEK293, His)
氨肽酶 N/APN 蛋白是一种二硫键同源三聚体,充当广泛特异性氨肽酶。它在肽消化、肽加工、抗原呈递、血管生成和胆固醇结晶中发挥着至关重要的作用。APN 蛋白还与氨基酸转运蛋白 SLC6A19 相互作用,并在感染过程中充当人类冠状病毒 229E/HCoV-229E 的受体。Aminopeptidase N/APN 蛋白, Human (HEK293, His) 是重组的 氨肽酶 N/APN 蛋白,由 HEK293 表达,带有 C-His 标签。
- Dilute-Free Rapid Gold BCA Protein Assay
GLPbio的Dilute-Free Rapid Gold BCA Protein Assay是基于改良 BCA(Bicinchoninic Acid) 法的即用型蛋白质定量检测试剂盒,5分钟室温孵育即可进行检测。
- ent-[Amyloid β-Protein (20-16)]-β-Ala-D-Lys(ent-[Amyloid β-Protein (16-20)])CAS: 1426174-31-3
This all-D peptide contains two retro-inverso peptide klvff motifs of KLVFF (H-3682) corresponding to amino acids 16 to 20 of amyloid β-protein. The tandem dimer retro-inverso peptide showed about a 100-fold higher binding affinity (Kd = 1.3 . 10?² µM) for amyloid β-protein (1-40) fibrils than KLVFF (Kd = 1.1 ± 0.3 µM). It was also found to be more effective in preventing ordered fibril formation than the parent peptide KLVFF as judged by its increased ability to inhibit thioflavin T binding to β-sheet structures.
- [pGlu4]-Myelin Basic Protein Peptide (trifluoroacetate salt)
[pGlu]-Myelin basic protein peptide is a substrate for PKC.
- Carboxypeptidase A(≥20 units/mg protein)CAS: 11075-17-5
羧肽酶A能水解蛋白质和多肽底物C端芳香族或中性脂肪族氨基酸残基,释放除脯氨酸、羟脯氨酸、精氨酸和赖氨酸之外的所有C末端氨基酸,更易于水解具有芳香族侧链和大脂肪侧链的羧基端氨基酸。比如酪氨酸,苯丙氨酸,丙氨酸等。 羧肽酶A(carboxypeptidase A),CPA, 因其底物的首位字"A"而得名羧肽酶A 。
- LSD1 Protein, Human (sf9, His-GST)
LSD1 蛋白是一种组蛋白去甲基化酶,通过对“Lys-4”(H3K4me) 和“Lys-9”(H3K9me) 去甲基化来修饰组蛋白 H3。它充当共激活剂或辅阻遏物,通过 FAD 氧化底物,生成随后水解的亚胺。LSD1 蛋白, Human (sf9, His-GST) 是重组的 LSD1 蛋白,由 Sf9 insect cells 表达,带有 N-His, N-GST 标签。
- Protein Disulfide Isomerase from bovine liverCAS: 37318-49-3
来自牛肝的蛋白质二硫键异构酶(PDI)是一种分子量107 kDa的同型二聚体,单体为57 kDa。等电点(pI)大约为4.2。
- (Des-Glu²²)-Amyloid β-Protein (1-40)CAS: 1678416-36-8
The Osaka mutation was the first deletion-type mutation to be identified in APP and Aβ. The Aβ E22delta mutant is more resistant to degradation by two major Aβ-degrading enzymes, neprilysin and insulin-degrading enzyme. Synthetic mutant Aβ showed unusual aggregation properties with enhanced oligomerization but no fibrillization. It also inhibited hippocampal long-term potentiation more efficiently than wild-type Aβ. A transgenic mouse model containing APP with the E693delta mutation has been developed. APP(OSK)-Tg mice exhibit intraneuronal Aβ E22delta oligomers and memory impairment as early as eight months of age.
- (Gln²²,Asn²³)-Amyloid β-Protein (1-40)CAS: 374796-75-5
Transgenic mice expressing the vasculotropic Dutch/Iowa (E693Q/D694N) mutant human Aβ precursor protein in brain (Tg-SwDI) accumulate abundant cerebral microvascular fibrillar amyloid deposits and exhibit robust neuroinflammation. In vitro, the doubly mutated Aβ peptides showed an increased propensity to fibrillation and pathogenicity compared to the Dutch and Iowa single mutants.
- (Met(O)³⁵)-Amyloid β-Protein (1-40)CAS: 178302-50-6
Oxidation of Met35 attenuates the formation of Aβ40 oligomers.
- (Met(O)³⁵)-Amyloid β-Protein (1-42)CAS: 1802086-68-5
(Met(O)³?)-Amyloid β-protein (1-42) (H-5888), in contrast to Aβ 1-42 (H-1368), has been shown to be non-toxic to 9-11 day-old rat embryonic hippocampal neuronal cultures and not to produce any protein oxidation. It has also been demonstrated that fibril formation is not affected by Met(O)³?. For the Nle analog see H-7308.
- (Met(O₂)³⁵)-Amyloid β-Protein (1-42)CAS: 1802086-69-6
Maiti et al. could show that, in contrast to the sulfoxide of Aβ (1-42), the sulfone was as toxic and aggregated as fast as wild-type Aβ (1-42).
- 5-FAM-Amyloid β-Protein (1-40)CAS: 1678416-08-4
5-FAM-Amyloid β;-Protein (1-40) 是 FAM 荧光标记的 β;-Amyloid (1-40) 肽(Λex=492nm 和 Λem=518nm)。
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GP10006 | Myelin Basic Protein (68-82), guinea pig | 98474-59-0 | Peptides | ||
髓鞘碱性蛋白 (68-82),豚鼠是髓鞘碱性蛋白 (MBP) 的片段。 | |||||
| GA24128 | HIV-1 tat Protein (47-57) amide | 697226-52-1 | Peptides | ||
HIV-1 tat Protein (47-57) is a potent cell penetrating peptides. | |||||
| GC69285 | Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) (TFA) | - | Peptides | ||
Interphotoreceptor Retinoid Binding Protein Fragment (IRBP) TFA,具有 20 个残基肽,也是主要的致病表位,存在于光受体间类视黄醇结合蛋白肽 (IRBP 161-180) 的第一个同源重复中, 可引起后葡萄膜炎 (EAU)。 | |||||
| GC27280 | Aminopeptidase N/APN Protein, Human (HEK293, His) | - | - | ||
氨肽酶 N/APN 蛋白是一种二硫键同源三聚体,充当广泛特异性氨肽酶。它在肽消化、肽加工、抗原呈递、血管生成和胆固醇结晶中发挥着至关重要的作用。APN 蛋白还与氨基酸转运蛋白 SLC6A19 相互作用,并在感染过程中充当人类冠状病毒 229E/HCoV-229E 的受体。Aminopeptidase N/APN 蛋白, Human (HEK293, His) 是重组的 氨肽酶 N/APN 蛋白,由 HEK293 表达,带有 C-His 标签。 | |||||
| GK10043 | Dilute-Free Rapid Gold BCA Protein Assay | - | - | ||
GLPbio的Dilute-Free Rapid Gold BCA Protein Assay是基于改良 BCA(Bicinchoninic Acid) 法的即用型蛋白质定量检测试剂盒,5分钟室温孵育即可进行检测。 | |||||
| GA21423 | ent-[Amyloid β-Protein (20-16)]-β-Ala-D-Lys(ent-[Amyloid β-Protein (16-20)]) | 1426174-31-3 | Amyloid β protein | ||
This all-D peptide contains two retro-inverso peptide klvff motifs of KLVFF (H-3682) corresponding to amino acids 16 to 20 of amyloid β-protein. The tandem dimer retro-inverso peptide showed about a 100-fold higher binding affinity (Kd = 1.3 . 10?² µM) for amyloid β-protein (1-40) fibrils than KLVFF (Kd = 1.1 ± 0.3 µM). It was also found to be more effective in preventing ordered fibril formation than the parent peptide KLVFF as judged by its increased ability to inhibit thioflavin T binding to β-sheet structures. | |||||
| GC90558 | Myelin Basic Protein Peptide Antagonist (trifluoroacetate salt) | - | Peptides | ||
一种MBP拮抗剂 | |||||
| GC91844 | [pGlu4]-Myelin Basic Protein Peptide (trifluoroacetate salt) | - | Enzyme Substrates | ||
[pGlu]-Myelin basic protein peptide is a substrate for PKC. | |||||
| GB10021 | Carboxypeptidase A(≥20 units/mg protein) | 11075-17-5 | - | ||
羧肽酶A能水解蛋白质和多肽底物C端芳香族或中性脂肪族氨基酸残基,释放除脯氨酸、羟脯氨酸、精氨酸和赖氨酸之外的所有C末端氨基酸,更易于水解具有芳香族侧链和大脂肪侧链的羧基端氨基酸。比如酪氨酸,苯丙氨酸,丙氨酸等。 羧肽酶A(carboxypeptidase A),CPA, 因其底物的首位字"A"而得名羧肽酶A 。 | |||||
| GC26726 | AKT1 Protein, Human (Active, sf9, GST) | - | - | ||
AKT1 蛋白是 AKT 激酶家族的一部分,对于代谢、增殖、存活、生长和血管生成至关重要。 | |||||
| GC27195 | LSD1 Protein, Human (sf9, His-GST) | - | - | ||
LSD1 蛋白是一种组蛋白去甲基化酶,通过对“Lys-4”(H3K4me) 和“Lys-9”(H3K9me) 去甲基化来修饰组蛋白 H3。它充当共激活剂或辅阻遏物,通过 FAD 氧化底物,生成随后水解的亚胺。LSD1 蛋白, Human (sf9, His-GST) 是重组的 LSD1 蛋白,由 Sf9 insect cells 表达,带有 N-His, N-GST 标签。 | |||||
| GC27026 | Protein Disulfide Isomerase from bovine liver | 37318-49-3 | - | ||
来自牛肝的蛋白质二硫键异构酶(PDI)是一种分子量107 kDa的同型二聚体,单体为57 kDa。等电点(pI)大约为4.2。 | |||||
| GC31170 | Calmodulin-Dependent Protein Kinase II 290-309 | 115044-69-4 | Peptides | ||
A CaMKII inhibitor | |||||
| GA20095 | (Des-Glu²²)-Amyloid β-Protein (1-40) | 1678416-36-8 | Amyloid β protein | ||
The Osaka mutation was the first deletion-type mutation to be identified in APP and Aβ.
The Aβ E22delta mutant is more resistant to degradation by two major Aβ-degrading enzymes, neprilysin and insulin-degrading enzyme. Synthetic mutant Aβ showed unusual aggregation properties with enhanced oligomerization but no fibrillization. It also inhibited hippocampal long-term potentiation more efficiently than wild-type Aβ. A transgenic mouse model containing APP with the E693delta mutation has been developed. APP(OSK)-Tg mice exhibit intraneuronal Aβ E22delta oligomers and memory impairment as early as eight months of age. | |||||
| GA20184 | (Gln²²,Asn²³)-Amyloid β-Protein (1-40) | 374796-75-5 | Amyloid β protein | ||
Transgenic mice expressing the vasculotropic Dutch/Iowa (E693Q/D694N) mutant human Aβ precursor protein in brain (Tg-SwDI) accumulate abundant cerebral microvascular fibrillar amyloid deposits and exhibit robust neuroinflammation. In vitro, the doubly mutated Aβ peptides showed an increased propensity to fibrillation and pathogenicity compared to the Dutch and Iowa single mutants. | |||||
| GA20251 | (Met(O)³⁵)-Amyloid β-Protein (1-40) | 178302-50-6 | Amyloid β protein | ||
Oxidation of Met35 attenuates the formation of Aβ40 oligomers. | |||||
| GA20252 | (Met(O)³⁵)-Amyloid β-Protein (1-42) | 1802086-68-5 | Amyloid β protein | ||
(Met(O)³?)-Amyloid β-protein (1-42) (H-5888), in contrast to Aβ 1-42 (H-1368), has been shown to be non-toxic to 9-11 day-old rat embryonic hippocampal neuronal cultures and not to produce any protein oxidation. It has also been demonstrated that fibril formation is not affected by Met(O)³?. For the Nle analog see H-7308. | |||||
| GA20253 | (Met(O)³⁵)-Amyloid β-Protein (25-35) | 292147-12-7 | Amyloid β protein | ||
Sulfoxide of Aβ 25-35. | |||||
| GA20254 | (Met(O₂)³⁵)-Amyloid β-Protein (1-42) | 1802086-69-6 | Amyloid β protein | ||
Maiti et al. could show that, in contrast to the sulfoxide of Aβ (1-42), the sulfone was as toxic and aggregated as fast as wild-type Aβ (1-42). | |||||
| GA20433 | 5-FAM-Amyloid β-Protein (1-40) | 1678416-08-4 | Amyloid β protein | ||
5-FAM-Amyloid β;-Protein (1-40) 是 FAM 荧光标记的 β;-Amyloid (1-40) 肽(Λex=492nm 和 Λem=518nm)。 | |||||
| GA20435 | 5-FAM-Amyloid β-Protein (1-42) | 1802087-78-0 | Amyloid β protein | ||
