关于 "Cancer stem cell" 的结果26+ 个结果

A cellular senescence detection reagent

一种BCRP抑制剂

一氧化氮生产阻滞剂

A PD-1/PD-L1 interaction inhibitor

PD-1/PD-L1 inhibitor N11 is an inhibitor of the protein-protein interaction between programmed cell death protein 1 (PD-1) and PD-1 ligand (PD-L1; IC50 = 6.3 nM).

A cell-permeable and positively charged tetrazolium dye

An inducer of immunogenic cancer cell death

OT-82 is a novel nicotinamide phosphoribosyltransferase (NAMPT) inhibitor with average IC50s of 13.03 ??nM in non-HP cancer cells and 2.89? ?nM in HP cancer cells, respectively.

TJ191 is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells.

Glycerol tributyrate (Tributyrin) is a triglyceride that may inhibit cell growth and induce cell differentiation.

A cell-permeable ceramide analog

A tumor cell-differentiating agent

RA-9 is a cell-permeable, potent and selective inhibitor of proteasome-associated deubiquitinating enzymes (DUBs) with favorable toxicity profile and anticancer activity. RA-9 selectively induces apoptosis in ovarian cancer cell lines.

Picrocrocin, the chemical most responsible for the bitter taste of saffron, is isolated from saffron and inhibits proliferation of cancer cells.

ZINC05007751 is a potent NIMA-related kinase NEK6 inhibitor with an IC50 of 3.4 μM, shows antiproliferative activity against a panel of human cancer cell lines and displays a synergistic effect with Cisplatin and Paclitaxel in a BRCA2 mutated ovarian cancer cell line. DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation.

740 Y-P是一种PI3K激活剂，浓度为20μM 。

ErSO activates the anticipatory unfolded protein response (a-UPR) with an IC50 of 20.3 nM in MCF-7 cells. ErSO induces rapid and selective necrosis of ERα-positive breast cancer cell lines in vitro.

N6F11 is a novel, selective and potent inducer of iron death with anticancer and antitumour activity that promotes GPX4 degradation by binding to TRIM25 in cancer cells.

A lipid decomposition product with cancer inhibiting activity

Triglycidyl Isocyanurate (Teroxirone, Tris(2,3-epoxypropyl) Isocyanurate, TGI, TGIC) is a triazene triepoxide with antineoplastic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl Isocyanurate alkylates and cross-links DNA, thereby inhibiting DNA replication. Triglycidyl Isocyanurate is also used in various polyester powder coatings in the metal finishing industry.

An NSAID-NO donor hybrid with anti-cancer activity

Single enantiomer of a potent inhibitor of a cancer-promoting enzyme

T cell activator

A mast cell tryptase inhibitor