关于 "c-RET" 的结果19 个结果
- gamma-Secretase ModulatorsCAS: 937812-80-1
gamma-Secretase Modulators (Amyloid-β production inhibitor)是淀粉状蛋白β生成抑制剂，可作用于阿尔茨海默病。
- β-Secretase Inhibitor IVCAS: 797035-11-1
β-Secretase Inhibitor IV可与BACE-1活性位点结合并有效阻断其蛋白水解活性（IC₅₀=15nM）。
- Secretin (human) (trifluoroacetate salt)
A gastrointestinal hormone and neuropeptide
- Mca-HQKLVFFA-K(Dnp)-NH2 (trifluoroacetate salt)
A fluorogenic substrate for α-secretase
- DAPT (GSI-IX)CAS: 208255-80-5
DAPT (GSI-IX) 是一种具有口服活性的 γ-分泌酶抑制剂，对人原代神经元培养物中产生的总淀粉样蛋白-β (Aβ) 和 Aβ42 的 IC50 分别为 115 nM 和 200 nM。
- Orexin A amide (bovine, human, mouse, rat) (trifluoroacetate salt)
A hypothalamic neuropeptide
- BetazoleCAS: 105-20-4
Betazole Dihydrochloride (Ametazole, 2-(3-Pyrazolyl)ethanamine) is a histamine H2 agonist used clinically to test gastric secretory function.
- Betazole DihydrochlorideCAS: 138-92-1
Betazole Dihydrochloride (Ametazole, 2-(3-Pyrazolyl)ethanamine) is a histamine H2 agonist used clinically to test gastric secretory function.
- Verubecestat (MK-8931) TrifluoroacetateCAS: 2095432-65-6
Verubecestat (MK-8931) Trifluoroacetate is a potent and selective beta-secretase inhibitor and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor.
| 货号 | 产品名称 | CAS号 | 靶点 / 通路 | 引用 | 结构 |
|---|---|---|---|---|---|
| GC36110 | gamma-Secretase Modulators | 937812-80-1 | Amyloid β | ||
gamma-Secretase Modulators (Amyloid-β production inhibitor)是淀粉状蛋白β生成抑制剂，可作用于阿尔茨海默病。 | |||||
| GC18464 | β-Secretase Inhibitor IV | 797035-11-1 | Beta-secretase | ||
β-Secretase Inhibitor IV可与BACE-1活性位点结合并有效阻断其蛋白水解活性（IC₅₀=15nM）。 | |||||
| GC44881 | Secretin (human) (trifluoroacetate salt) | - | Neuroendocrinology | ||
A gastrointestinal hormone and neuropeptide | |||||
| GC48327 | Secretin (rat) (trifluoroacetate salt) | - | Neuroendocrinology | ||
A neuropeptide hormone | |||||
| GC44130 | Mca-EVKMDAEF-K(Dnp)-NH2 (ammonium salt) | - | Alzheimer | ||
A fluorogenic substrate for β-secretase | |||||
| GC44131 | Mca-HQKLVFFA-K(Dnp)-NH2 (trifluoroacetate salt) | - | Alzheimer | ||
A fluorogenic substrate for α-secretase | |||||
| GC12942 | DAPT (GSI-IX) | 208255-80-5 | Autophagy | ||
DAPT (GSI-IX) 是一种具有口服活性的 γ-分泌酶抑制剂，对人原代神经元培养物中产生的总淀粉样蛋白-β (Aβ) 和 Aβ42 的 IC50 分别为 115 nM 和 200 nM。 | |||||
| GC39798 | Scoulerine | 6451-73-6 | Microtubule/Tubulin | ||
A benzylisoquinoline alkaloid with diverse biological activities | |||||
| GC49553 | Orexin B amide (human) (trifluoroacetate salt) | - | Neuropeptides | ||
A hypothalamic neuropeptide | |||||
| GC49558 | Orexin B amide (mouse, rat) (trifluoroacetate salt) | - | Neuropeptides | ||
A hypothalamic neuropeptide | |||||
| GC52507 | Orexin A amide (bovine, human, mouse, rat) (trifluoroacetate salt) | - | Obesity | ||
A hypothalamic neuropeptide | |||||
| GC17367 | Rebamipide | 90098-04-7 | Prostaglandin Receptor | ||
A gastroprotective agent and mucin secretagogue | |||||
| GC12096 | Semagacestat (LY450139) | 425386-60-3 | Notch | ||
A pan γ-secretase inhibitor | |||||
| GC11309 | ARN2966 | 102212-26-0 | Amyloid β | ||
An inhibitor of APP production and Aβ secretion | |||||
| GC18568 | JNJ-40418677 | 1146594-87-7 | Alzheimer | ||
A modulator of γ-secretase | |||||
| GC45459 | GHRP-6 (acetate) | 145177-42-0 | Behavioral Neuroscience | ||
A growth hormone secretagogue and GHS-R agonist | |||||
| GC61539 | Betazole | 105-20-4 | Histamine Receptor | ||
Betazole Dihydrochloride (Ametazole, 2-(3-Pyrazolyl)ethanamine) is a histamine H2 agonist used clinically to test gastric secretory function. | |||||
| GC25136 | Betazole Dihydrochloride | 138-92-1 | Histamine Receptor | ||
Betazole Dihydrochloride (Ametazole, 2-(3-Pyrazolyl)ethanamine) is a histamine H2 agonist used clinically to test gastric secretory function. | |||||
| GC26035 | Verubecestat (MK-8931) Trifluoroacetate | 2095432-65-6 | BACE | ||
Verubecestat (MK-8931) Trifluoroacetate is a potent and selective beta-secretase inhibitor and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. | |||||